Bis-Glyceryl Ascorbate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Bis-Glyceryl Ascorbate?

Bis-Glyceryl Ascorbate is a modern form of vitamin C in which two glycerin molecules are linked to an ascorbic acid core. The glycerin parts make the vitamin more water loving and more stable, so it keeps its power longer in a cream or serum. It is usually derived from plant based glycerin and lab made ascorbic acid, then joined together in a controlled reaction that takes place in a sterile, temperature-regulated vessel. This tweak on classic vitamin C was first explored in the early 2000s when chemists searched for milder, longer-lasting antioxidants for everyday skincare. Today you are most likely to see Bis-Glyceryl Ascorbate in brightening serums, daily moisturizers, sheet masks, anti-aging lotions and light gel creams because it plays well with both water and oil phases and remains gentle on skin.

Bis-Glyceryl Ascorbate’s Cosmetic Benefits/Uses

This ingredient adds value to a formula in two key ways

  • Antioxidant – Helps neutralize free radicals that can lead to dull tone and early lines, supporting a fresher, more even look
  • Humectant – Attracts and holds water in the upper layers of skin, promoting a soft, plump feel and boosting overall hydration levels

Who Can Use Bis-Glyceryl Ascorbate

Because Bis-Glyceryl Ascorbate blends the hydrating nature of glycerin with the brightening action of vitamin C it suits most skin types, including dry, dehydrated, oily, combination and normal. Sensitive skin usually tolerates it better than traditional ascorbic acid since the molecule is less acidic and more stable, though anyone with very reactive skin should introduce it slowly in case of individual intolerance. There is no specific drawback for acne-prone skin because the ingredient is lightweight and water friendly, so it will not clog pores on its own.

The compound is generally produced from plant derived glycerin and lab synthesized vitamin C which makes it a vegan and vegetarian-friendly option, provided the finished product does not include animal sourced additives elsewhere in the formula.

No data points to risks for pregnant or breastfeeding women when Bis-Glyceryl Ascorbate is applied topically in cosmetic amounts. Still, this statement is not medical advice and anyone who is pregnant or nursing should ask a healthcare professional before adding new skincare products to their routine.

Unlike some exfoliating acids or retinoids this form of vitamin C does not cause photosensitivity, yet daily sunscreen remains essential for overall skin health and to maximize brightening results.

Potential Side Effects/Adverse Reactions

Responses to topical Bis-Glyceryl Ascorbate differ from person to person. The points below outline potential side effects that may occur, although most users will not experience them when the ingredient is formulated and used as intended.

  • Mild redness or warmth
  • Temporary stinging on very sensitive or compromised skin
  • Rare allergic contact dermatitis presenting as itching or small bumps
  • Increased dryness if layered with multiple strong actives lacking adequate moisturizers

If any unwanted reaction develops discontinue use and consult a medical professional to determine the appropriate next steps.

Comedogenic Rating

Rating: 0 out of 5

This vitamin C derivative is completely water soluble and has a lightweight molecular size, so it does not mingle with sebum or linger in pores. The glycerin segments attract water, not oil, and studies as well as user reports show no tendency to create blockages or whiteheads.

Thanks to this non pore clogging profile Bis-Glyceryl Ascorbate is generally a safe pick for acne-prone or breakout-prone skin.

Keep in mind that the finished formula still matters. If the product also contains heavy oils, waxes or butters overall comedogenicity could rise even though Bis-Glyceryl Ascorbate itself stays at zero.

Summary

Bis-Glyceryl Ascorbate offers a double benefit in skincare: it fights free radicals to maintain a bright even tone, and it pulls moisture into the skin surface for a soft hydrated feel. The molecule delivers these perks by pairing antioxidant vitamin C activity with the water loving nature of glycerin, all in a more stable and gentle format than pure ascorbic acid.

While it is not yet as mainstream as classic vitamin C, more formulators are turning to it for daily serums, gel creams and sheet masks because it stays potent longer and works for a wider range of skin types.

Safety data and real world use point to a low risk of irritation or pore clogging, although very sensitive individuals could experience mild redness or stinging. Trying any new product on a small patch of skin first is always a wise step to confirm personal tolerance.

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