Bis-Hydroxyethoxypropyl Dimethicone/Peg-2 Soyamine/Ipdi Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Bis-Hydroxyethoxypropyl Dimethicone/Peg-2 Soyamine/Ipdi Copolymer?

Bis-Hydroxyethoxypropyl Dimethicone/PEG-2 Soyamine/IPDI Copolymer is a man-made silicone blend created by linking three building blocks: a water-loving form of dimethicone, a soybean-based amine that has been joined to a short piece of polyethylene glycol, and a small ring-shaped molecule called isophorone diisocyanate. Chemists combine these parts in a controlled heating step so they bond into a long, flexible chain known as a copolymer. The result is a silky liquid or soft wax that spreads easily and leaves a smooth feel on skin and hair.

Silicones entered beauty labs in the 1950s but early versions could feel heavy or build up. By the late 1990s researchers were grafting natural-sourced pieces like soy amines onto silicone backbones to boost slip while keeping formulas light. Adding IPDI to the reaction let the chains crosslink just enough to resist wash-off. This newer copolymer soon showed up in salon conditioners and leave-in sprays and is now also common in skin primers, light moisturizers, BB creams, anti-frizz serums, sheet masks and setting sprays.

Bis-Hydroxyethoxypropyl Dimethicone/Peg-2 Soyamine/Ipdi Copolymer’s Cosmetic Benefits/Uses

This ingredient earns its place in formulas by covering several helpful roles at once

  • Film forming – It lays down an invisible, flexible film that locks in moisture, adds shine and helps other active ingredients stay put longer
  • Hair conditioning – The soy-derived amine portion carries a slight positive charge that clings to the negatively charged spots on damaged hair, smoothing rough cuticles, cutting static and making strands easier to comb
  • Emollient – The silicone backbone glides over skin or hair filling in tiny gaps so surfaces feel soft, silky and non-greasy

Who Can Use Bis-Hydroxyethoxypropyl Dimethicone/Peg-2 Soyamine/Ipdi Copolymer

This silicone-soy copolymer is lightweight and non-greasy so it works for dry, oily, combination and sensitive skin alike. Its breathable film helps hold moisture without clogging pores which makes it a good choice even for those prone to breakouts. The only group that may want to steer clear are individuals with a known sensitivity to silicones or soy-derived ingredients, though such reactions are uncommon.

Because the soyamine portion is sourced from plants and the rest of the molecule is fully synthetic, the ingredient contains no animal derivatives and is generally considered suitable for vegetarians and vegans. Still, if a finished product carries additional animal-based additives, overall vegan status would depend on the full formula.

Pregnant or breastfeeding users are not expected to absorb meaningful amounts of this large polymer through intact skin, and no reproductive toxicity has been reported. This is not medical advice, however, and anyone who is expecting or nursing should discuss any skincare product with a qualified healthcare provider to be safe.

The copolymer does not make skin more prone to sunburn and has no known photosensitizing effect. It also plays well with most common actives so there are no special timing rules or layer-separation issues to worry about.

Potential Side Effects/Adverse Reactions

Responses to topical Bis-Hydroxyethoxypropyl Dimethicone/Peg-2 Soyamine/Ipdi Copolymer can vary from person to person. The points below list potential reactions, but when the ingredient is used at normal cosmetic levels most people experience none of them.

  • Mild skin irritation such as redness or itchiness in those sensitive to silicones or soy
  • Allergic contact dermatitis in rare cases of true allergy
  • Eye stinging or watering if the product accidentally gets into the eyes
  • Build-up on hair after very frequent use which can leave strands flat or coated until washed with a clarifying shampoo

If any discomfort or persistent reaction develops stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 / 5 – The large silicone-soy polymer sits on top of skin rather than seeping into pores, has a low molecular weight fraction and contains no greasy plant oils that tend to clog. Published tests on similar dimethicone blends show minimal comedone formation even on oily skin panels, so the risk is considered very low.

Suitable for people who are prone to acne or breakouts because its lightweight breathable film is unlikely to trap sebum or debris.

As with any leave-on silicone, heavy layering with multiple products can create surface build-up that might feel occlusive to some users, but this is a texture issue rather than true pore blockage.

Summary

Bis-Hydroxyethoxypropyl Dimethicone/PEG-2 Soyamine/IPDI Copolymer acts as a film former, hair conditioner and emollient. The silicone backbone spreads smoothly, the soyamine portion gives mild positive charge so the polymer clings to hair and skin, and the IPDI crosslinks lend durability. Together these features lock in moisture, add slip, tame frizz and leave a silky finish without greasiness.

While not as famous as plain dimethicone, this copolymer appears in a growing number of lightweight primers, sprays and leave-in conditioners where a barely-there feel is prized.

Safety data and long consumer use suggest it is well tolerated with only rare irritation or allergy. Patch test any new product that contains it to be on the safe side.

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