Bis-Methoxy Peg-40 Polyepsilon Caprolactone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
Share:
Inside this article:

All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Bis-Methoxy Peg-40 Polyepsilon Caprolactone?

Bis-Methoxy Peg-40 Polyepsilon Caprolactone is a lab made polymer that joins two building blocks: polyethylene glycol and epsilon caprolactone. The “PEG-40” part shows that the polyethylene glycol section has an average chain length of 40 repeating units, while “bis-methoxy” points to small side groups that improve water solubility. The material starts with plant or petroleum based raw ethylene oxide, which is reacted with methanol to give methoxy-ended PEG. Chemists then add epsilon caprolactone through a ring opening process, linking many caprolactone rings onto the PEG backbone. Careful control of time, temperature and catalysts sets the final molecular weight and texture.

The ingredient first appeared in personal care in the late 1990s when formulators looked for gentle surfactants that could clean skin without stripping moisture. Its mixed oil-loving and water-loving parts made it handy for rinse-off and leave-on products. Today it shows up in facial cleansers, makeup removers, micellar waters, shampoos, bath gels, sheet masks, lightweight lotions and even some spray on serums where a clear finish is needed.

Bis-Methoxy Peg-40 Polyepsilon Caprolactone’s Cosmetic Benefits/Uses

This versatile polymer helps a formula do its job while keeping the product pleasant to use.

  • Cleansing – lifts away dirt, oil and leftover makeup, then helps them rinse off with water so skin and hair feel fresh but not tight
  • Emulsifying – blends water with oils, silicones or fragrance so the final product stays smooth and uniform, cuts oily feel and gives a lightweight texture

Who Can Use Bis-Methoxy Peg-40 Polyepsilon Caprolactone

This ingredient is gentle enough for most skin types including sensitive, oily, combination and acne prone skin. Very dry or eczema-prone skin might want extra moisturising ingredients alongside it since repeated cleansing can remove some surface lipids.

Bis-Methoxy Peg-40 Polyepsilon Caprolactone is made from plant or petroleum sourced raw materials and contains no animal derivatives so it is generally considered suitable for vegans and vegetarians. Always check the full product formula if strict animal-free certification is important to you.

Current safety data shows no specific risks during pregnancy or breastfeeding when used topically in normal cosmetic levels. This is not medical advice and anyone who is pregnant or nursing should confirm the suitability of any skincare product with a healthcare professional to be sure.

The polymer itself does not make skin more sensitive to sunlight and it has no known photoreactive groups so it will not increase sunburn risk. It is also fragrance-free and compatible with most other common skincare actives which makes it easy to slot into a routine.

Potential Side Effects/Adverse Reactions

Individual responses to topical Bis-Methoxy Peg-40 Polyepsilon Caprolactone can vary. The points below outline potential side effects that have been reported in rare cases. When used at cosmetic levels most people will not experience any of these problems.

  • Mild transient stinging or redness, especially on broken or freshly exfoliated skin
  • Dry or tight feeling if used in a high-foam cleanser without adequate follow-up hydration
  • Contact dermatitis in individuals with a specific polymer or PEG sensitivity
  • Watery eyes or irritation if the product accidentally gets into the eyes

If you develop persistent irritation or any unexpected reaction stop using the product and consult a medical professional.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Bis-Methoxy Peg-40 Polyepsilon Caprolactone is highly water soluble and does not form an oily film that could block pores. Its large polymer size keeps it on the skin surface where it rinses away easily, leaving little residue. These traits place it at the very bottom of the comedogenic scale.

Because it earns a 0 rating it is generally suitable for people who are prone to acne or frequent breakouts.

In leave-on products the overall formula still matters; heavy butters or waxes paired with this ingredient could shift the pore-clogging potential of the finished product.

Summary

Bis-Methoxy Peg-40 Polyepsilon Caprolactone works mainly as a gentle cleanser and an emulsifier. Its water-loving PEG side and oil-loving caprolactone side allow it to lift away grime while holding water and oil together so products stay smooth and clear.

It is a practical supporting actor rather than a headline star, so you will notice it more in ingredient lists of cleansers micellar waters and lightweight lotions than in splashy marketing campaigns.

Current safety data shows the polymer is well tolerated for most skin types with a very low risk of irritation or pore clogging. As with any new skincare step it is smart to do a small patch test when you first try a product containing Bis-Methoxy Peg-40 Polyepsilon Caprolactone just to check how your individual skin responds.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search