Bis-(Methyl Epoxidized Soyate) Peg-12: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Bis-(Methyl Epoxidized Soyate) Peg-12?

Bis-(Methyl Epoxidized Soyate) Peg-12 is a plant-derived ingredient that starts with soybean oil. The oil is first turned into methyl soyate, then the double bonds in the fatty acids are epoxidized to add small oxygen rings. Finally the epoxidized soyate is capped onto a short chain of polyethylene glycol containing twelve repeat units. The result is a lightweight liquid that mixes well with both water and oil, making it a handy bridge between the two.

Soybeans have long been used in food and industrial products, but interest in their cosmetic potential grew in the late 1990s when brands began looking for renewable alternatives to petroleum-based surfactants. Chemists found that joining epoxidized soyate to modest-sized PEG chains produced a gentle yet effective cleansing agent with extra formulating perks. Since then the material has appeared in a range of personal care launches focused on sustainability.

Manufacturing involves three main steps: transesterifying soybean oil to create methyl soyate, epoxidizing the methyl soyate with a peroxide under controlled conditions, then reacting the epoxidized product with PEG-12 through an end-capping process. The entire route can be carried out at moderate temperatures and uses readily available catalysts, which helps keep costs and environmental impact low.

You will most often spot Bis-(Methyl Epoxidized Soyate) Peg-12 in facial cleansers, micellar waters, lightweight moisturizers, makeup removers, sheet mask essences and gentle hair conditioners. Its multitasking nature also makes it a supporting player in sunscreens and anti-aging serums where keeping oils, actives and water evenly blended is crucial.

Bis-(Methyl Epoxidized Soyate) Peg-12’s Cosmetic Benefits/Uses

This ingredient pulls double and sometimes triple duty inside formulas, improving both how a product works and how it feels on the skin.

  • Cleansing: Its surfactant properties lift away dirt, excess oil and makeup without stripping natural moisture so products feel mild yet effective
  • Dispersing: Helps pigments, sunscreen particles and botanical extracts stay evenly suspended which prevents clumping and ensures uniform coverage on skin or hair
  • Emulsifying: Acts as a link between oil and water phases allowing creams, lotions and serums to stay stable over time while keeping textures light and silky
  • Solubilizing: Makes it possible to dissolve small amounts of fragrance oils or lipophilic actives into clear water-based formulas such as toners and mists

Who Can Use Bis-(Methyl Epoxidized Soyate) Peg-12

Because it is a mild surfactant and lightweight emulsifier, Bis-(Methyl Epoxidized Soyate) Peg-12 works well for most skin types including oily, combination, normal and even dry or sensitive complexions. Its balanced oil in water character helps cleanse without leaving a heavy residue so it suits acne-prone skin while the gentle action avoids the tight feeling that sensitive users often dislike. People with very reactive or highly compromised skin should still review the full formula of any product that contains it to be sure other ingredients are appropriate.

The ingredient is sourced from soybeans and synthetic polyethylene glycol, neither of which comes from animals, so it is considered vegan and vegetarian friendly.

Current safety data show no specific issues for women who are pregnant or breastfeeding when Bis-(Methyl Epoxidized Soyate) Peg-12 is used in rinse-off or leave-on cosmetics. Its large molecular size limits absorption through intact skin. This is not medical advice and anyone who is expecting or nursing should discuss all skincare choices with a qualified healthcare provider.

Bis-(Methyl Epoxidized Soyate) Peg-12 does not make skin more sensitive to sunlight and does not interfere with sunscreen ingredients. Although the soy base is highly processed, individuals with a known soy allergy may wish to proceed with caution and monitor for any signs of irritation.

Potential Side Effects/Adverse Reactions

Responses to topical Bis-(Methyl Epoxidized Soyate) Peg-12 can differ from one person to another. The effects listed below are possibilities only and are unlikely to be experienced by most users when the ingredient is used at cosmetic levels in a properly formulated product.

  • Temporary redness or mild stinging, especially on very sensitive or freshly exfoliated skin
  • Allergic contact dermatitis in rare cases, more likely in individuals already allergic to soy
  • Eye irritation if the raw ingredient or a concentrated formula accidentally gets into the eyes
  • Increased penetration of stronger actives in the same product which could heighten their side effect profile

If any irritation or discomfort develops stop using the product and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 1/5

Bis-(Methyl Epoxidized Soyate) Peg-12 scores a low 1 because its molecule is fairly large and stays mostly on the skin surface where it helps oils mix with water then rinses away cleanly. It does not leave a greasy film that might block pores, and it lacks the heavy saturated fats linked to breakouts.

For most people who are prone to acne this ingredient is unlikely to trigger new spots and is generally considered suitable.

The only time a higher risk might appear is if the formula pairs it with thick occlusive oils or if it is used in a very high concentration inside a leave-on product, which is uncommon.

Summary

Bis-(Methyl Epoxidized Soyate) Peg-12 is a soy-based multitasker that cleanses, emulsifies, disperses and solubilizes. Its PEG side gives it a water-loving edge while the epoxidized soy tail grabs onto oily grime so it lifts away dirt, keeps pigments even and blends oil and water into stable light textures.

Although not a household name it is gaining quiet popularity among brands focused on greener sourcing and gentle formulas because it replaces harsher petroleum surfactants without sacrificing performance.

Current research shows it is low risk for irritation or sensitization and its large size limits skin penetration. As with any new skincare ingredient a small patch test is a smart step before full use, especially for those with very reactive skin.

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