What Is Bis-Palmitoyloxycapramido Isopropanol?
Bis-Palmitoyloxycapramido Isopropanol is a lipid-based ingredient created by linking palmitic acid, capric acid and isopropanol to a small amino-alcohol backbone. The result is a waxy, skin-friendly molecule that looks and behaves a lot like the natural fats found in the outer layer of our skin. First developed in the early 2000s as chemists searched for gentler alternatives to petrolatum, it quickly caught the eye of cosmetic formulators for its silky feel and barrier-boosting talent.
Manufacturing starts with plant-derived palmitic and capric fatty acids, most often sourced from palm or coconut oil. These fatty acids are purified then reacted with a bio-based isopropanol derivative under controlled heat and vacuum. The finished material is filtered and milled into a fine powder or soft flakes that melt easily into creams and lotions.
You will usually spot Bis-Palmitoyloxycapramido Isopropanol in products that aim to replenish moisture and smooth texture, such as day and night creams, anti-aging serums, restorative face masks, hand creams, lip treatments and soothing after-sun formulas. Because it is oil-soluble and stable, formulators also add it to long-wear makeup and tinted moisturizers to keep them comfortable on the skin.
Bis-Palmitoyloxycapramido Isopropanol’s Cosmetic Benefits/Uses
This multifunctional ingredient brings several perks to personal care formulas:
- Skin Conditioning: Helps skin feel softer and look more even by supporting its natural lipid balance and reducing rough patches
- Emollient: Fills in microscopic gaps between skin cells to create a smooth surface and reduce water loss, giving an instant silky finish
- Skin Protecting: Forms a light breathable film that shields skin from environmental stress like wind or low humidity while reinforcing the skin barrier over time
Who Can Use Bis-Palmitoyloxycapramido Isopropanol
Thanks to its skin-mimicking lipids, Bis-Palmitoyloxycapramido Isopropanol suits most skin types. Dry, normal and sensitive complexions usually welcome its comforting, non-greasy cushioning effect. Combination and mildly oily skin can also benefit provided formulas are lightweight and used in moderation; very oily or severely acne-prone skin may find richer creams containing it feel heavy.
The ingredient is made from plant-derived fatty acids and a bio-based alcohol so it is generally considered suitable for vegans and vegetarians. As always, check the full ingredient list because other components in a finished product could come from animal sources.
No studies have flagged concerns for pregnant or breastfeeding women when this material is applied topically. That said this is not medical advice and anyone who is pregnant or nursing should run any skincare product by their doctor first to be on the safe side.
Bis-Palmitoyloxycapramido Isopropanol does not absorb UV light or generate free radicals so it is not known to cause photosensitivity. It is also fragrance-free and compatible with most actives which makes it easy to slot into existing routines.
Potential Side Effects/Adverse Reactions
Reactions to topical Bis-Palmitoyloxycapramido Isopropanol vary from person to person. The points below list potential side effects only and they remain unlikely for the average user assuming the product has been formulated correctly.
- Mild temporary redness or stinging
- Clogged pores or breakouts in very oily skin when used in high-oil formulas
- Contact allergy in individuals sensitive to fatty acid derivatives (rare)
If you experience any adverse reaction stop using the product and consult a healthcare professional or dermatologist.
Comedogenic Rating
Rating: 2/5
Bis-Palmitoyloxycapramido Isopropanol is built from fatty acids that on their own can clog pores, yet once they are chemically linked into this larger ester the molecule becomes less able to seep deep into follicles. It sits mostly on the skin surface, melts at body temperature and forms a light film that reduces water loss without the heavy occlusion seen with ingredients like petrolatum or isopropyl palmitate. Because of this it earns a low-to-moderate score of 2 rather than the higher numbers typical of simpler fatty esters.
Most people prone to acne can use it if the overall formula is lightweight and low in other rich oils, though very oily skin might still prefer to skip it in heavier creams.
Formulation level matters: products using 1 percent or less of this ingredient rarely cause pore issues, while richer balms loaded with multiple waxy lipids may tip the balance toward congestion.
Summary
Bis-Palmitoyloxycapramido Isopropanol conditions, softens and protects skin by mimicking the natural lipids in the outer layer. Its waxy yet feather-light structure fills tiny gaps between cells, smooths texture and leaves behind a breathable shield that slows water loss so skin stays supple.
Although not a blockbuster name, it is gaining quiet popularity among formulators looking for plant-derived alternatives to mineral oil and silicone. You will spot it most often in barrier creams, night moisturizers and long-wear makeup that need a silky slip without greasiness.
Current safety data shows it is well tolerated with a low risk of irritation or sensitization. As with any new skincare ingredient it is wise to do a small patch test when trying a product that contains it, especially if you have reactive or acne-prone skin.