Botrytis Cinerea Ferment Lysate Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Botrytis Cinerea Ferment Lysate Filtrate?

Botrytis Cinerea Ferment Lysate Filtrate is a skin-conditioning liquid made from the controlled fermentation of Botrytis cinerea, a fungus often called gray mold and best known for its role in sweet wine production. During fermentation the organism produces a rich mix of amino acids, peptides, polysaccharides, enzymes and other small molecules that can soften and condition skin. To create the cosmetic ingredient, the fermented broth is lysed to break open the fungal cells, then carefully filtered to remove solids, leaving a clear, stable filtrate that blends easily into water-based formulas.

The cosmetic industry began looking at fermentation technology in the late twentieth century as a way to unlock gentle yet effective actives. Researchers noticed that the by-products of Botrytis cinerea fermentation had a silky feel and helped reduce moisture loss, so formulators started adding the filtrate to creams and lotions. Today you can spot Botrytis Cinerea Ferment Lysate Filtrate in moisturizers, hydrating serums, soothing masks, after-sun gels, hand creams and anti-aging treatments where a smooth, cushioned finish is desired.

Botrytis Cinerea Ferment Lysate Filtrate’s Cosmetic Benefits/Uses

In skincare formulas this ferment filtrate serves one main purpose that leads to a number of feel-good results for the user.

As an emollient, Botrytis Cinerea Ferment Lysate Filtrate fills the tiny gaps between dry surface cells, creating a soft flexible layer that boosts smoothness and helps the skin hold on to water. This cushioning action leaves skin feeling supple, improves the glide of the product during application and can lessen the appearance of rough or flaky patches over time.

Who Can Use Botrytis Cinerea Ferment Lysate Filtrate

This silky ferment filtrate is mild enough for almost all skin types, including dry, normal, combination, oily and even sensitive complexions. Because it is water based and lightweight it softens without leaving a greasy film so those prone to clogged pores often tolerate it well. It is produced from a fungus rather than from animals which makes it suitable for vegans and vegetarians, provided the finished product is certified free from animal derived processing aids.

No specific warnings exist for pregnant or breastfeeding women when the ingredient is applied topically in cosmetic amounts. That said this information does not replace medical advice and anyone who is expecting or nursing should show the full ingredient list of any product to a qualified healthcare provider before adding it to a routine.

The filtrate does not make skin more sensitive to sunlight so no extra sun precautions are required beyond the usual daily SPF habit. It is also compatible with most common actives such as niacinamide, vitamin C and retinoids.

Potential Side Effects/Adverse Reactions

Responses to topical Botrytis Cinerea Ferment Lysate Filtrate vary from person to person. The effects noted below are only potential outcomes and are not expected for the average user when the ingredient is properly formulated and preserved.

  • Mild redness or warming sensation shortly after application
  • Transient stinging on very compromised or freshly exfoliated skin
  • Allergic contact dermatitis in individuals with a specific sensitivity to fungal proteins
  • Worsening of pre existing fungal skin conditions in extremely rare cases
  • Eye irritation if the product migrates into the eyes

If any of these reactions occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1/5

Botrytis Cinerea Ferment Lysate Filtrate is water based, contains minimal lipids and absorbs quickly so it has little tendency to clog pores. Its molecules focus on surface softening rather than forming an occlusive film, which keeps the comedogenic risk low.

Suitable for acne-prone or breakout-prone skin in most cases.

The final product formula still matters: if the filtrate is paired with heavy oils or waxes the overall comedogenicity can rise, so always look at the complete ingredient list.

Summary

Botrytis Cinerea Ferment Lysate Filtrate is a fermented fungal extract that works as an emollient, filling in microscopic gaps between skin cells to boost smoothness, improve softness and reduce moisture loss. It does this with a mix of naturally generated amino acids, peptides and polysaccharides that sit lightly on the skin.

The ingredient is not a mainstream superstar yet, but it is slowly popping up in moisturizers, soothing serums and after-sun gels thanks to its silky feel and compatibility with many actives.

Safety data show it is generally well tolerated with a low risk of irritation or pore clogging. As with any new skincare addition, patch testing a small area first is a smart move to rule out individual sensitivities.

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