C10-30 Cholesterol/Lanosterol Esters: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is C10-30 Cholesterol/Lanosterol Esters?

C10-30 Cholesterol/Lanosterol Esters is a blend made by linking medium to long-chain fatty acids (those with 10 to 30 carbon atoms) to two natural skin lipids: cholesterol and lanosterol. Cholesterol is already present in human skin while lanosterol is a plant- and yeast-derived cousin that shares a similar ring structure. Chemists discovered in the late 1970s that turning these lipids into esters made them more stable, less greasy and easier to mix into creams. The manufacturing process usually starts with refined cholesterol and lanosterol extracted from wool grease or plant sterols. These raw materials react with purified fatty acids in the presence of a catalyst and gentle heat, forming a smooth waxy solid that can be milled into fine flakes or pellets.

Because the finished ester mimics some of the natural lipids found in the outer layer of skin, it has become a staple in modern skincare. You will most often spot it in moisturizers, age-defying serums, eye creams, overnight masks, lightweight lotions and makeup primers where a silky non-sticky feel is desired. It can also appear in sun care bases and specialty treatments aimed at repairing a weakened skin barrier.

C10-30 Cholesterol/Lanosterol Esters’s Cosmetic Benefits/Uses

This versatile ingredient offers several benefits to a formula

  • Skin conditioning – reinforces the skin’s lipid barrier helping to lock in moisture and leave the surface soft smooth and comfortable
  • Emulsifying – helps oil and water mix evenly so the product stays stable has a uniform texture and feels elegant on application
  • Viscosity controlling – thickens or fine-tunes the flow of creams and lotions so they dispense easily yet stay in place on the skin

Who Can Use C10-30 Cholesterol/Lanosterol Esters

This ester blend is generally well tolerated by most skin types. Dry and mature skin tend to benefit the most because the ingredient helps replace depleted lipids and reduces tightness. Normal and combination skin can also use it for an extra cushion of moisture without a heavy feel. Oily or acne-prone skin usually handles it fine thanks to a low comedogenic rating, though ultra-minimalist formulas may be preferred if you are very breakout sensitive.

Because the cholesterol portion is often sourced from wool grease, products containing C10-30 Cholesterol/Lanosterol Esters are unlikely to meet strict vegan standards. Some manufacturers do use plant sterols, so vegetarians or flexitarians may wish to check with the brand for sourcing details.

The ingredient has no known hormonal activity so it is considered safe for people who are pregnant or breastfeeding. This is not medical advice and anyone expecting or nursing should confirm suitability with a healthcare provider before adding new skincare products.

C10-30 Cholesterol/Lanosterol Esters does not increase photosensitivity and can be worn day or night without extra sun precautions beyond a daily SPF.

Potential Side Effects/Adverse Reactions

Side effects from topical use of C10-30 Cholesterol/Lanosterol Esters differ from person to person. The points below outline potential reactions, though most users will not encounter these issues when the ingredient is properly formulated and used as directed.

  • Mild redness or stinging in very sensitive skin during first applications
  • Breakouts in individuals highly prone to clogged pores if the overall formula is rich or layered with multiple occlusive products
  • Allergic contact dermatitis in people with a known sensitivity to lanolin or wool-derived ingredients due to trace impurities
  • Greasy feel or shine on extremely oily skin if applied in large amounts

If you experience any discomfort, breakout or rash stop using the product and seek advice from a qualified medical professional.

Comedogenic Rating

Rating: 1/5. C10-30 Cholesterol/Lanosterol Esters has a large, branched molecular structure that sits on the surface to supplement the skin barrier rather than slipping deep into pores. It provides a breathable lipid layer that is less likely to trap dead cells and sebum compared with heavier waxes or butters. Most formulation studies and user reports show little to no pore clogging even on combination skin.

Because of its low rating, the ingredient is generally considered suitable for people prone to acne or breakouts, especially when used in lightweight or gel-cream bases.

Keep in mind the overall formula matters. If the product also contains high levels of comedogenic oils or you layer several rich products, the risk of congestion rises regardless of this ester’s low score.

Summary

C10-30 Cholesterol/Lanosterol Esters conditions skin by replacing lost lipids, helps oil and water stay mixed for a smooth stable lotion and fine-tunes thickness so products glide on easily yet stay put. It achieves these jobs thanks to its dual nature: the cholesterol part binds well with skin lipids while the fatty acid chains lend just enough slip and structure to a formula.

The ester is a quiet workhorse that shows up in many moisturizers, eye creams and barrier repair products, though it rarely gets highlighted on the front label. Formulators like it because it delivers a luxurious feel without greasiness and plays nicely with active ingredients.

Safety data rate it as low risk with only rare reports of irritation or allergy. Still, skin is personal so it is wise to patch test any new product containing this ingredient to make sure it suits your unique needs.

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