C12-14 Sec-Alketh-40: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is C12-14 Sec-Alketh-40?

C12-14 Sec-Alketh-40 is a man-made ingredient created by attaching roughly forty units of ethylene oxide to a blend of secondary alcohols that come from mid-length synthetic fatty chains (with 12 to 14 carbon atoms). The result is a waxy, water-loving substance that mixes well with both oils and water.

The backbone alcohols that make up this material were first explored in the 1960s as detergents. When chemists discovered that adding long strings of ethylene oxide improved water solubility they began to tweak the ratios for personal care. By the late 1980s formulators adopted the 40-unit version for creams and hair products where a strong but gentle emulsifier was required.

Production starts with laboratory-made C12-14 secondary alcohols. These alcohols react with ethylene oxide gas in a controlled setting. Temperature pressure and catalysts guide the reaction until an average of forty ethoxy units attach to each alcohol molecule. The finished paste or flakes are then purified milled and packed for use.

Because it can hold oil and water together for long periods you will often find C12-14 Sec-Alketh-40 in moisturizers lotions leave-in hair conditioners face masks anti-aging serums cleansing balms and sunscreen formulations.

C12-14 Sec-Alketh-40’s Cosmetic Benefits/Uses

Formulators rely on this ingredient mainly for the way it handles mixtures of oil and water:

  • Emulsion stabilising: Keeps a formula from separating over time so the product remains smooth consistent and effective until the last drop
  • Emulsifying: Helps oil and water blend in the first place allowing creams lotions and milks to form quickly while feeling light on skin

Who Can Use C12-14 Sec-Alketh-40

This ingredient suits most skin types including normal oily combination and mature skin because it has a low irritation profile and does not clog pores. Those with very sensitive or barrier-impaired skin may notice slight dryness or itching since the molecule can pull some natural oils away during cleansing so a richer follow-up moisturizer is wise.

C12-14 Sec-Alketh-40 is fully synthetic with no animal by-products so it is compatible with vegan and vegetarian lifestyles.

The current data show no specific risks for women who are pregnant or breastfeeding when the ingredient is used in rinse-off or leave-on cosmetics. That said this is not medical advice and anyone who is expecting or nursing should have a healthcare professional review their routine for personal reassurance.

The molecule does not make skin more sensitive to sunlight and it does not interfere with common actives like retinoids or vitamin C so it can be used day or night without extra photo-protection beyond a standard broad-spectrum sunscreen.

Potential Side Effects/Adverse Reactions

Responses to topical C12-14 Sec-Alketh-40 differ from person to person. The issues listed below are possible but uncommon when the ingredient is formulated correctly and used as directed.

  • Mild skin irritation redness stinging or itching especially on already inflamed skin
  • Contact dermatitis rare allergic reaction leading to swelling or rash
  • Eye irritation temporary stinging if a product accidentally gets into the eyes
  • Scalp dryness slight flaking when used in shampoos for very dry or textured hair

If any of these reactions occur stop using the product immediately and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 1 out of 5. C12-14 Sec-Alketh-40 is a large water-soluble molecule that acts mostly on the surface of the skin rather than sinking into pores. Because it is highly hydrophilic and is usually used at low levels to keep oil and water mixed it is unlikely to block follicles or trap sebum. For people prone to acne or breakouts it is generally considered safe and unlikely to trigger new blemishes.

The only situation that might raise its pore-clogging potential is when it appears in a very rich formula loaded with heavy oils or waxes. In that case congestion would be more related to the other ingredients than to C12-14 Sec-Alketh-40 itself.

Summary

C12-14 Sec-Alketh-40 serves two main jobs: it helps oil and water join together forming a stable emulsion and it keeps that mixture from separating while the product sits on the shelf or on the skin. It does this by positioning its water-loving ethoxy chains in the aqueous phase while its fatty alcohol backbone anchors into the oil phase creating a flexible bridge between the two.

While not a headline star it is a quiet workhorse found in a fair number of creams lotions sunscreens and leave-in hair products where dependable yet gentle emulsification is needed.

Current safety data show a low risk of irritation or allergy when the ingredient is used at normal cosmetic levels. Still skin can be unpredictable so it is wise to patch test any new product that lists C12-14 Sec-Alketh-40 to ensure personal compatibility.

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