What Is Caffeoyl Sh-Decapeptide-23?
Caffeoyl Sh-Decapeptide-23 is a lab made peptide that carries a caffeoyl group, a natural antioxidant piece taken from caffeic acid found in many plants. The peptide part is a chain of ten amino acids designed to mimic signals that help skin look fresher and more resilient. By linking the two parts scientists get an ingredient that delivers both the protective power of antioxidants and the targeted action of a bioactive peptide.
The compound is produced through solid phase peptide synthesis, a step-by-step process where each amino acid is added in a precise order. After the chain is built the caffeoyl group is attached, then the finished material is purified and dried into a fine powder that blends easily into cosmetic bases. The method keeps the ingredient free from animal material and suitable for vegan formulas.
Peptides started gaining beauty-world attention in the early 2000s for their firming benefits. As research grew, brands began pairing peptides with antioxidant groups to create multitasking actives. Caffeoyl Sh-Decapeptide-23 is one of the new generation of such hybrids and has been used in products since the late 2010s.
You will most often spot it in lightweight serums, anti-aging creams, eye gels, sheet masks, after-sun lotions and daily moisturizers aimed at fighting dullness or early signs of aging.
Caffeoyl Sh-Decapeptide-23’s Cosmetic Benefits/Uses
This ingredient offers two key functions that work in harmony to support healthier looking skin.
- Antioxidant: The caffeoyl part helps neutralize free radicals created by UV light and pollution. By cutting down oxidative stress it may reduce the appearance of fine lines and keep skin tone more even.
- Skin Protecting: The peptide section encourages the skin’s own defense signals, helping it stay resilient against everyday irritants. This protective boost can make the skin barrier feel stronger and better hydrated.
Who Can Use Caffeoyl Sh-Decapeptide-23
Caffeoyl Sh-Decapeptide-23 is gentle enough for most skin types including normal, dry, oily and combination skin. Its soothing antioxidant profile also makes it a good option for sensitive or redness-prone skin since it does not contain known irritants like fragrance or drying alcohol. People with an established allergy to peptides or caffeic derivatives should avoid it as a precaution, though such sensitivities are rare.
The ingredient is synthesized entirely in the lab without animal by-products so it fits vegan and vegetarian lifestyles. No animal-derived carriers or enzymes are used during manufacturing which keeps it in line with cruelty-free standards practiced by many clean beauty brands.
There are no published concerns about topical Caffeoyl Sh-Decapeptide-23 for women who are pregnant or breastfeeding. Still, research on pregnancy-specific safety is limited which is why it is best to have any product reviewed by a healthcare professional before use to stay on the safe side.
The molecule itself does not make skin more sensitive to sunlight, so it will not raise your risk of sunburn. Regular daytime SPF is still important because UV exposure produces free radicals that this peptide is designed to fight in the first place.
Potential Side Effects/Adverse Reactions
Side effects and reactions to topical Caffeoyl Sh-Decapeptide-23 differ from person to person. The points below cover potential issues only and most users will not experience them when the ingredient is properly formulated and used as directed.
- Mild redness or warmth shortly after application
- Temporary stinging on very compromised or freshly exfoliated skin
- Localized rash or hives in individuals allergic to peptides or caffeic compounds
- Increased dryness if paired with high concentrations of strong exfoliating acids that disrupt the skin barrier
- Product instability or loss of efficacy when stored at high temperatures leading to unexpected texture or odor changes
If any irritation or discomfort develops stop using the product and consult a healthcare professional for guidance.
Comedogenic Rating
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Caffeoyl Sh-Decapeptide-23 is a small water-soluble peptide free of heavy oils or waxes so it carries virtually no pore-clogging potential. It sits on the surface, delivers its benefits then absorbs or rinses away without blocking follicles.
This makes it suitable for acne-prone or breakout-prone skin.
Remember the finished product matters too: rich butters, thick silicones or other occlusive ingredients in the same formula can still cause congestion even if the peptide itself does not.
Summary
Caffeoyl Sh-Decapeptide-23 supplies two jobs in one: the caffeoyl piece sweeps up free radicals while the decapeptide nudges skin into strengthening its own defenses. The result is smoother looking, better protected skin with less dullness.
It is not yet a blockbuster ingredient but its multitasking profile is gaining quiet traction in modern serums, eye gels and after-sun formulas.
Overall safety data is reassuring with low irritation and no photo sensitivity, plus it is vegan friendly. Still, every complexion is unique so do a simple patch test when trying a new product that features this peptide just to stay on the safe side.