Caffeoyl Sh-Decapeptide-9: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Caffeoyl Sh-Decapeptide-9?

Caffeoyl Sh-Decapeptide-9 is a lab crafted chain of ten amino acids that has been linked with a caffeoyl group, a plant derived molecule found in coffee beans and many fruits. By joining these two parts scientists created a small yet stable peptide that mimics signals naturally made by the skin to look smooth and healthy. The ingredient was first explored in the early 2010s when peptide research took off in the beauty world as brands searched for milder alternatives to strong actives like retinoids. It is produced through solid phase peptide synthesis, a precise step-by-step process that strings together each amino acid. Once the decapeptide is built, it is coupled with caffeic acid to add antioxidant support then purified and dried into a fine powder ready for formulas. You will usually see Caffeoyl Sh-Decapeptide-9 in lightweight anti aging serums, eye creams that target fine lines, revitalizing sheet masks, night moisturizers and post-treatment soothing gels.

Caffeoyl Sh-Decapeptide-9’s Cosmetic Benefits/Uses

This ingredient serves one main role in skincare: skin conditioning. By helping to support the skin’s natural repair signals the peptide encourages a smoother surface, improved elasticity and a fresh looking glow. The added caffeoyl group provides mild antioxidant action that can help shield the complexion from everyday environmental stress. Formulators like it because it is water soluble, works well at low levels and pairs nicely with hydrators such as hyaluronic acid or glycerin.

Who Can Use Caffeoyl Sh-Decapeptide-9

Most skin types can enjoy products featuring Caffeoyl Sh-Decapeptide-9 because the peptide is lightweight non greasy and generally non irritating. Dry complexions appreciate the added conditioning boost while oily or combination skin benefits from the ingredient’s water soluble texture that will not clog pores. Extremely reactive or compromised skin should proceed cautiously only because any new active may feel tingly on a damaged barrier rather than due to a known risk specific to this peptide.

The peptide is produced entirely in a lab without animal derived raw materials so formulas using it are usually suitable for vegans and vegetarians. Brands may still vary in their choice of other ingredients so anyone following a strict lifestyle should double check the full ingredient list and look for clear cruelty free or vegan labeling.

Current research has not flagged Caffeoyl Sh-Decapeptide-9 as unsafe for pregnant or breastfeeding women when used topically at the low concentrations found in cosmetics. Still this is not medical advice and those who are expecting or nursing should share any planned skincare routine with a qualified health professional to be on the safe side.

The ingredient does not increase photosensitivity and can be used morning or night. Daily sunscreen is however always a smart habit to protect the skin from ultraviolet damage.

Potential Side Effects/Adverse Reactions

Responses to topical Caffeoyl Sh-Decapeptide-9 differ from person to person. The points below outline potential reactions that could occur even though most users will not experience them when the ingredient is properly formulated and applied.

  • Temporary redness or warmth right after application, especially on very sensitive skin
  • Mild stinging or itching that subsides within minutes
  • Localized irritation if layered with highly acidic or exfoliating products
  • Rare allergic contact dermatitis resulting in swelling or rash
  • Eye irritation if the formula accidentally migrates into the eyes

If any of these effects occur stop using the product and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0

Caffeoyl Sh-Decapeptide-9 is a small water soluble peptide with no heavy oils or waxes, so it leaves no residue that could trap sebum or dead skin cells. Its lightweight profile means it is highly unlikely to clog pores even on oily or combination skin.

It is therefore suitable for people who are prone to acne or breakouts.

Remember the overall formula still matters, so pore blockage can occur if the peptide is paired with richer emollients in the final product.

Summary

Caffeoyl Sh-Decapeptide-9 is a ten-amino-acid peptide linked to a caffeoyl group that conditions skin by supporting its natural repair signals, promoting smoother texture better elasticity and a healthy glow. The caffeoyl portion adds a light antioxidant boost that helps guard against everyday environmental stress.

While peptides are popular, this specific molecule remains a niche choice found mainly in focused anti aging serums, eye creams and post-treatment gels. Its gentle nature and easy compatibility with other actives may increase its presence as brands look for mild yet effective ingredients.

Studies show it is safe for most users at cosmetic levels with minimal risk of irritation or pore blockage. Still, perform a quick patch test when trying any new product containing Caffeoyl Sh-Decapeptide-9 to ensure your skin agrees with it.

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