Calcium Polyglutamate Crosspolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
Share:
Inside this article:

All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Calcium Polyglutamate Crosspolymer?

Calcium Polyglutamate Crosspolymer is a large, water-friendly molecule created by linking together many units of calcium polyglutamate with a plant-derived agent called glyceryl triglycidyl ether. Calcium polyglutamate itself comes from glutamic acid, an amino acid that can be sourced from fermented sugar beets or corn. By crosslinking the chains, chemists produce a stable, sponge-like network that performs reliably in skincare formulas.

The idea of using glutamic acid derivatives in beauty products has been around since the early 2000s when brands were looking for gentler, plant-based thickeners. As polymer technology advanced, researchers discovered that adding calcium ions and a glycerol-based crosslinker made the material even more versatile, which led to its adoption in moisturizers and masks.

Manufacturing starts with fermenting plant sugars to obtain glutamic acid. The acid is neutralized with calcium to form calcium polyglutamate, then reacted with glyceryl triglycidyl ether under heat and pH control. The resulting gel-like polymer is washed, dried and milled into a fine powder that disperses easily in water or oil.

You will usually spot Calcium Polyglutamate Crosspolymer in creamy or gel-based products such as daily moisturizers, hydrating masks, anti aging serums, sunscreens, lightweight lotions, primers and targeted treatment ampoules.

Calcium Polyglutamate Crosspolymer’s Cosmetic Benefits/Uses

This multitasking polymer supports both the texture and performance of a formula.

  • Emulsion stabilising: Keeps oil and water phases from separating so the product stays smooth and uniform from the first pump to the last
  • Film forming: Creates an invisible, flexible layer on the skin that locks in moisture, boosts softness and can improve wear time of makeup placed on top
  • Skin conditioning: Attracts and holds water on the skin surface giving an immediate plumping effect and a more comfortable, hydrated feel

Who Can Use Calcium Polyglutamate Crosspolymer

Thanks to its lightweight water-binding nature, Calcium Polyglutamate Crosspolymer suits nearly every skin type. Dry or mature complexions benefit from the moisture-locking film it creates, normal skin enjoys extra softness without heaviness, and oily or combination skin appreciates that the polymer does not add greasy residue. Even sensitive skin generally tolerates it well because it is non-acidic and free of common irritants.

The ingredient is produced from plant-fermented glutamic acid and a glycerol-based crosslinker, so it is suitable for both vegetarians and vegans when sourced from suppliers that avoid animal testing.

Current data suggests topical use is safe for women who are pregnant or breastfeeding since the large polymer molecules sit on the skin surface rather than penetrating into the bloodstream. This is not medical advice and anyone expecting or nursing should still confirm product choices with a healthcare professional.

Calcium Polyglutamate Crosspolymer is not known to cause photosensitivity, so it does not make skin more vulnerable to sunburn. Standard daytime sun protection practices are still recommended whenever using skincare.

Potential Side Effects/Adverse Reactions

Reactions to topical Calcium Polyglutamate Crosspolymer vary between individuals. The points below outline potential but uncommon side effects when the ingredient is used in a finished cosmetic that has been properly formulated.

  • Mild redness or stinging in very sensitive skin
  • Transient tight feeling if applied in a formula that lacks additional emollients
  • Rare clogged pores for those extremely prone to congestion when heavy layers are applied repeatedly
  • Contact dermatitis in people allergic to any component of the finished product

If you experience any of these effects, stop using the product and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 1 / 5. Calcium Polyglutamate Crosspolymer is a hefty, water-loving polymer that sits on the skin surface rather than seeping into pores, and it is not oily or waxy, so it rarely traps sebum or debris. While any film-forming agent could in theory contribute to congestion if layered with rich occlusives, the ingredient itself has minimal clogging potential. It is generally considered suitable for people who are prone to acne or breakouts. If a product also contains heavy butters or oils, overall pore-clogging risk will depend on the full formula, not just this polymer.

Summary

Calcium Polyglutamate Crosspolymer works as an emulsion stabiliser, a film former and a skin-conditioning humectant. Its crosslinked calcium-glutamate chains absorb water and swell, creating a micro-sponge that thickens creams, keeps oil and water phases mixed and leaves behind a light, flexible veil that reduces moisture loss and boosts smoothness.

Although not yet a household name, it is gaining quiet popularity with formulators looking for plant-derived, vegan-friendly texture enhancers that do more than just thicken. Its multitasking nature means you may spot it in an increasing range of moisturisers, sunscreens and primers.

Safety data show a low risk of irritation or sensitisation thanks to the large molecular size and neutral pH. As with any new skincare ingredient it is smart to patch test a product before full-face use, especially if you have very reactive skin.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search