Calcium Sodium Phosphosilicate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Calcium Sodium Phosphosilicate?

Calcium Sodium Phosphosilicate is a synthetic powder made by fusing together sand and mineral oxides rich in silicon, calcium, sodium and phosphorus, then rapidly cooling the melted mixture to form what chemists call bioactive glass. First created in the late 1960s for bone repair, it found its way into oral care in the 2000s when researchers noticed that the material bonded well with tooth enamel. Today it is produced on an industrial scale through a melt quench process that yields tiny, porous particles able to react with saliva. Because of its ability to release helpful minerals, it now appears in toothpastes, whitening powders, desensitizing gels and some mouth rinses aimed at strengthening teeth and easing sensitivity.

Calcium Sodium Phosphosilicate’s Cosmetic Benefits/Uses

In cosmetic oral care formulas Calcium Sodium Phosphosilicate provides one core benefit.

As an oral care agent it reacts with saliva to release calcium and phosphate ions that form a layer of hydroxyapatite on the tooth surface. This new mineral layer helps block open dentin tubules so it can reduce tooth sensitivity, reinforce weak spots in enamel for a smoother brighter look, and offer gentle cleaning without harsh abrasion.

Who Can Use Calcium Sodium Phosphosilicate

This ingredient is considered gentle and non irritating, so products that contain it are generally suitable for all skin types including dry, oily, combination and sensitive. Because it is a mineral powder that stays within the mouth rather than on facial skin it poses virtually no risk of clogging pores or triggering breakouts.

Calcium Sodium Phosphosilicate is entirely synthetic and made only from mineral oxides, with no animal derived substances or processing aids, so it is appropriate for both vegetarians and vegans.

Current research has not flagged any specific concerns for women who are pregnant or breastfeeding when the ingredient is used in toothpaste or other rinse off oral care. That said this is not medical advice and anyone who is pregnant or nursing should confirm suitability with a healthcare professional before adding a new product to their routine just to be on the safe side.

The ingredient does not make skin or oral tissues more sensitive to sunlight, so photosensitivity is not an issue.

People with very high sodium restrictions imposed by a physician may wish to discuss frequent use with their dentist, although the amount of sodium released during brushing is minimal.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Calcium Sodium Phosphosilicate can vary from person to person. The points below list potential issues but they are uncommon and most users experience none when the ingredient is formulated correctly.

  • Mild gum or oral tissue irritation
  • Temporary gritty sensation if particles are not fully rinsed away
  • Subtle change in taste perception immediately after brushing
  • Very rare allergic response such as redness swelling or tingling
  • Excess enamel wear if combined with overly aggressive brushing technique

If any discomfort or unexpected reaction occurs stop using the product and seek advice from a dentist or physician.

Comedogenic Rating

Rating: 0 out of 5. Calcium Sodium Phosphosilicate is an inert mineral glass that does not mix with skin oils or leave a residue capable of blocking pores. It is formulated for use inside the mouth and is rinsed away quickly, so it never sits on facial skin long enough to cause congestion.

This makes the ingredient suitable for anyone prone to acne or breakouts.

The only meaningful contact it might have with facial skin is a little toothpaste foam around the lips, and that brief exposure poses no comedogenic concern.

Summary

Calcium Sodium Phosphosilicate works in oral care by releasing calcium and phosphate ions that re-form a hydroxyapatite layer on teeth, easing sensitivity, reinforcing weak enamel and giving a smoother brighter surface while cleaning gently.

It is moderately popular, found mostly in targeted sensitive toothpastes, whitening powders and professional desensitizing gels rather than every everyday formula.

The ingredient is considered very safe with a low risk of irritation or allergy. Still, when trying any new product that contains it, do a quick patch test or small-area trial to make sure it agrees with you.

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