Cannabidiol Trisiloxane: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cannabidiol Trisiloxane?

Cannabidiol Trisiloxane is a hybrid molecule that links cannabidiol, the well-known compound from hemp, to a short chain of three silicone units called a trisiloxane. By combining a plant-based ingredient with a lightweight silicone backbone, chemists created a material that keeps the skin-loving traits of cannabidiol while adding the smooth feel and spreadability typical of silicones.

The idea of merging CBD with silicones emerged in the late 2010s when formulators sought easier ways to add oil-soluble actives to water-based products. Through a controlled reaction, purified cannabidiol is bonded to a trisiloxane segment, producing a clear fluid that stays stable in a wide range of cosmetic bases.

Because it helps oils and pigments disperse evenly and leaves a breathable film on skin or hair, Cannabidiol Trisiloxane is now found in face serums, light moisturizers, primers, foundations, sheet masks, anti-aging creams and even leave-in hair treatments. Its dual nature lets brands tout the buzz of CBD without the greasiness that pure hemp extracts can bring.

Cannabidiol Trisiloxane’s Cosmetic Benefits/Uses

This ingredient supports a formula in two key ways:

  • Dispersing Non-Surfactant: It keeps pigments, oils and other actives evenly suspended so the product looks uniform and applies smoothly. Good dispersion also means users need less rubbing to spread the product, which can reduce irritation.
  • Film Forming: After application it sets into a thin flexible layer that locks in moisture, enhances wear time for makeup and gives skin or hair a soft silky finish without feeling heavy.

Who Can Use Cannabidiol Trisiloxane

Thanks to its lightweight silicone backbone, Cannabidiol Trisiloxane is generally well tolerated by all skin types including oily, dry, combination and even most sensitive complexions. It is non-greasy, non-occlusive and unlikely to clog pores, though anyone with a known silicone allergy should avoid it.

The compound is made from plant derived cannabidiol and laboratory produced silicones, so it contains no animal ingredients and is suitable for both vegans and vegetarians. As always, cruelty-free status depends on the finished brand’s policies.

Current research has not flagged specific risks for topical use during pregnancy or breastfeeding, yet data are still limited. This is not medical advice; expectant or nursing mothers should discuss any product containing Cannabidiol Trisiloxane with their healthcare provider before use.

Cannabidiol Trisiloxane does not increase photosensitivity, so it will not make skin more prone to sunburn. It can be paired with daily sunscreen for complete protection.

Potential Side Effects/Adverse Reactions

Responses to topical Cannabidiol Trisiloxane vary from person to person. The following are potential side effects that could occur, although they are uncommon when the ingredient is properly formulated and used as directed.

  • Mild redness, itching or stinging
  • Allergic contact dermatitis in individuals sensitive to cannabidiol or silicones
  • Temporary acne-like breakouts in very pore-clogging-prone skin
  • Eye irritation if the product migrates into the ocular area
  • Build-up on hair shafts leading to dullness if used repeatedly without clarifying shampoos

If you experience any of the above reactions, stop using the product and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 1/5

Cannabidiol Trisiloxane sits at the low end of the scale because its short silicone chain is too lightweight to form a heavy occlusive layer that blocks pores, and cannabidiol itself is not known to provoke breakouts. The molecule spreads thinly, leaves minimal residue and is typically incorporated at low percentages, all of which keep its clogging potential mild.

This rating means it is generally suitable for skin that is prone to acne or congestion.

As with any silicone-based ingredient, overall pore-friendliness also depends on the full formula and how thoroughly the product is removed, especially in leave-on makeup.

Summary

Cannabidiol Trisiloxane acts as a dispersing aid and film former, helping pigments and oils stay evenly mixed while laying down a breathable silky layer that locks in moisture and extends wear. Its hybrid CBD-silicone structure lets brands tap into the buzz of hemp actives without the greasy feel of raw extracts, making it attractive for lightweight serums, primers and hair care.

The ingredient is still a niche addition rather than a mainstream staple, mostly found in innovative or premium formulations aimed at clean beauty fans who want the benefits of CBD with a smoother cosmetic finish.

Topically it ranks as low risk with rare reports of irritation or pore clogging, and it is considered vegan friendly and non-photosensitizing. As with any new skincare ingredient it is smart to perform a small patch test when trying a product that contains Cannabidiol Trisiloxane to ensure personal compatibility.

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