Cannabisamidopropyl Dimethylamine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cannabisamidopropyl Dimethylamine?

Cannabisamidopropyl Dimethylamine is a plant-derived compound made by joining fatty acids from hemp seed oil with a small nitrogen-containing molecule called dimethylamine. The result is a gentle, water-loving surfactant that carries a positive charge. Work on hemp-based surfactants picked up in the early 2000s when formulators began seeking greener, silicone-free ways to smooth hair and stabilize creams. To produce the ingredient, manufacturers first press hemp seeds to obtain oil, isolate its fatty acids, react them with dimethylamine, then neutralize and purify the mixture. You can spot Cannabisamidopropyl Dimethylamine in rinse-off and leave-in conditioners, anti-frizz sprays, cleansing milks, lightweight lotions, and curl-defining gels.

Cannabisamidopropyl Dimethylamine’s Cosmetic Benefits/Uses

Below is a look at how this multifunctional ingredient can improve a formulation

  • Antistatic: Reduces static buildup on hair strands so styles stay sleek and flyaways are minimized
  • Hair Conditioning: Deposits a thin film that makes hair feel softer, look shinier, and comb more easily when wet or dry
  • Emulsifying: Helps oil and water stay blended, giving lotions and creams a smooth, even texture that does not separate over time
  • Viscosity Controlling: Fine-tunes thickness so products pour, spread, or pump just the way consumers expect

Who Can Use Cannabisamidopropyl Dimethylamine

This hemp-based conditioning agent is considered gentle enough for all skin and hair types, including dry, oily and color-treated strands. Its lightweight film does not clog pores so even acne-prone skin usually tolerates it well. Those with extremely reactive or eczema-prone skin should still monitor for any personal sensitivity since it is a cationic surfactant.

Because the ingredient is sourced from hemp seed oil and involves no animal-derived components, it is suitable for vegans and vegetarians provided the finished product as a whole aligns with cruelty-free standards.

No data suggest a special risk for people who are pregnant or breastfeeding. Absorption through intact skin is expected to be minimal, yet this is not medical advice and anyone expecting or nursing should review new personal-care products with a healthcare provider to be on the safe side.

Cannabisamidopropyl Dimethylamine does not cause photosensitivity so daytime use does not require extra sun precautions beyond normal sunscreen habits.

Potential Side Effects/Adverse Reactions

Reactions to topical Cannabisamidopropyl Dimethylamine vary from person to person. The points below outline potential side effects, though most users will not experience them when products are formulated and used correctly.

  • Mild eye irritation if product unintentionally enters the eyes
  • Transient scalp or skin redness in individuals with very sensitive skin
  • Contact dermatitis in rare cases of allergy to hemp-derived ingredients
  • Product buildup that can leave hair limp or dull when high concentrations are left on without proper rinsing

If any undesirable reaction occurs stop using the product rinse the area thoroughly and seek medical advice if symptoms persist.

Comedogenic Rating

Rating: 1 / 5

Cannabisamidopropyl Dimethylamine earns a low score because its molecules are water loving, positively charged and tend to rinse clean without lodging in pores. While it can leave a slight conditioning film on hair and skin, the layer is thin and breathable so it seldom traps oil or debris. The ingredient also appears in low percentages, especially in rinse-off products, further reducing any clogging risk. For these reasons it is generally considered safe for acne-prone users.

No data suggest it aggravates fungal acne and it is compatible with lightweight formulas designed for oily skin.

Summary

Cannabisamidopropyl Dimethylamine is a hemp-derived multitasker that tames static, conditions hair, binds oil and water and tweaks thickness. Its cationic head sticks to negatively charged hair shafts smoothing cuticles while the fatty tail adds softness and shine. In emulsions the same amphiphilic structure positions itself between oil droplets keeping creams stable and silky.

The ingredient is still a niche choice compared with long-established quats yet interest is rising as brands look for plant sourced silicone alternatives.

Overall safety is high with only rare reports of irritation or buildup. As with any new cosmetic ingredient it is wise to patch test a product before full use just to stay on the safe side.

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