Cannabisamidopropyl Hydroxysultaine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cannabisamidopropyl Hydroxysultaine?

Cannabisamidopropyl Hydroxysultaine is a gentle surfactant created from fatty acids naturally present in hemp seed oil. Chemically it is a zwitterion, meaning one end of the molecule carries a positive charge while another holds a negative charge, so it balances itself and works well with other ingredients. It first drew attention when brands looked for plant based alternatives to harsher cleansing agents and the growing popularity of cannabis derived actives made hemp a logical starting point.

The ingredient is produced in several steps. Fatty acids from cold-pressed hemp seed oil are converted into an amidoamine, reacted with propyl groups then neutralized with a sultone to form the inner salt structure that gives the material its mild performance and rich foam. The finished liquid is usually clear or slightly amber and has a low odor, making it easy to scent and color.

You will most often see Cannabisamidopropyl Hydroxysultaine in rinse off products such as shampoos, body washes, facial cleansers, bubble baths and baby washes, but formulators also slip it into micellar waters, sheet masks or clay masks when they want a bit of cleansing action without stripping the skin. Some lightweight moisturizers and anti-aging serums include small amounts to boost texture or help oil and water stay mixed.

Cannabisamidopropyl Hydroxysultaine’s Cosmetic Benefits/Uses

Below are the main roles this ingredient can play inside a formula

  • Skin Conditioning – leaves a soft hydrated feel after rinsing so skin does not feel tight
  • Cleansing – lifts away dirt oil and makeup while staying mild enough for daily use
  • Emulsifying – helps oil and water phases blend evenly which improves stability and texture
  • Foam Boosting – creates a dense creamy lather that consumers associate with effective cleansing even in low sulfate washes
  • Viscosity Controlling – thickens formulations so gels and washes feel rich and stay put in the palm or on a loofah

Who Can Use Cannabisamidopropyl Hydroxysultaine

Because it is a mild surfactant that balances its own charge, Cannabisamidopropyl Hydroxysultaine tends to work well for nearly every skin type. Dry or mature skin benefits from its conditioning feel, oily and acne-prone skin appreciates its light cleansing that does not leave a residue and sensitive skin usually tolerates it because it contains no sulfates or common irritants. The only group that might need extra caution is anyone with a known allergy to hemp derivatives or to cocamidopropyl-type ingredients, as there is a small chance of cross-reactivity.

The material is sourced from hemp seed oil, a plant origin raw material, and no animal by-products are used during processing so it is suitable for vegans and vegetarians.

Current safety data indicate no specific concerns for women who are pregnant or breastfeeding when the ingredient is used in typical rinse-off or leave-on concentrations. This is not medical advice and anyone expecting or nursing should review the full ingredient list of any cosmetic with a healthcare professional before use to be extra cautious.

Cannabisamidopropyl Hydroxysultaine does not cause photosensitivity, so it will not make skin more prone to sunburn. It is also non-ionic in finished formulations so it plays nicely with most actives, preservatives and fragrances without lowering their performance.

Potential Side Effects/Adverse Reactions

Reactions to the topical use of Cannabisamidopropyl Hydroxysultaine vary from person to person. The points below outline potential side effects although they are uncommon when the ingredient is used at standard cosmetic levels.

  • Mild transient stinging if applied to broken or highly compromised skin
  • Redness or itchiness in individuals allergic to hemp derivatives
  • Localized rash or contact dermatitis in users sensitive to betaine-type surfactants
  • Eye irritation such as watering or slight burning if the product accidentally gets into the eyes
  • Excess scalp dryness when used in very high concentrations or with other strong cleansers

If any of these effects occur stop using the product immediately and consult a medical professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 / 5

Cannabisamidopropyl Hydroxysultaine is fully water soluble and designed to rinse away instead of sitting on the skin. Because it does not leave an oily film or clog pores, formulators consider it non comedogenic. Its primary role is cleansing and foam boosting, which actually helps remove pore-blocking debris rather than add to it.

That makes the ingredient suitable for people who are prone to acne or frequent breakouts.

The only time pore issues might arise is if the finished product also contains high levels of heavy oils or butters; in that case the overall formula, not this surfactant, would be the culprit.

Summary

Cannabisamidopropyl Hydroxysultaine is a multitasking hemp-derived surfactant that conditions skin, cleanses gently, keeps oil and water mixed, adds lush foam and thickens washes so they feel luxurious. It performs these jobs thanks to its zwitterionic structure, which lets it interact with both oily grime and rinse-water while staying mild.

The ingredient is still a niche choice compared with classic coconut betaines, but its plant origin and gentle profile are driving steady interest among indie haircare and body wash brands.

Current data show it is low risk for irritation, non comedogenic and appropriate for most skin types including sensitive. As with any new cosmetic though it is wise to patch test a product that contains it to make sure your skin agrees with the full formula.

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