Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid?

Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid is a lab-crafted molecule that belongs to the benzothiazine family of compounds. Its backbone combines a ring of sulfur and nitrogen with a side chain that includes a caprylyloxy group, giving it both oil-loving and water-friendly parts. This balanced design lets the ingredient blend smoothly into creams and serums without separating.

Researchers first explored benzothiazine derivatives in the early 2000s while searching for stable antioxidants that could survive heat and light in cosmetic formulas. By adding the caprylyloxyphenylamino side chain and two extra methyl groups, chemists boosted both the stability and skin affinity of the molecule. After safety testing and refinement it started appearing in skin care launches around 2015, mainly in premium anti-aging lines.

Production begins with plant-derived octanol, which is converted to caprylyl chloride and then attached to a phenylamine. This intermediate couples with a dimethyltetrahydro benzothiazine ring through controlled heating and catalysis. Finally, careful oxidation yields the carboxylic acid form that formulators prefer for its compatibility with a wide pH range.

You will most often spot this ingredient in leave-on products such as daily moisturizers, antioxidant serums, night creams, eye treatments, sheet masks and sunscreens that promise extra environmental defense. It is also added to some water-based mists and light lotions where brands want preservative support without traditional parabens.

Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid’s Cosmetic Benefits/Uses

This multitasker offers several perks when mixed into skin care formulas

  • Antioxidant – Helps neutralize free radicals from UV rays and pollution which can lead to dullness and early lines. By mopping up these unstable molecules it supports a brighter smoother look
  • Preservative – Slows the growth of microbes in the jar or bottle extending shelf life and reducing the need for stronger synthetic preservatives
  • Skin protecting – Forms a light invisible shield that supports the skin barrier and reduces moisture loss making the complexion feel soft and resilient

Who Can Use Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid

Thanks to its balanced oil and water affinity this ingredient tends to sit well with most skin types including dry oily combination and mature skin. Its lightweight feel and non-greasy finish mean even acne-prone users usually tolerate it without clogged pores while the barrier-supporting action can be soothing for dry or slightly sensitive complexions. Those with a known allergy to benzothiazine compounds or very reactive skin should approach with caution since the molecule still belongs to that family.

The compound is fully synthetic and the starting caprylyl chain is sourced from plant-derived octanol rather than animal by-products so it is generally viewed as suitable for vegans and vegetarians. As always final product certifications depend on the brand’s overall formulation and testing policies.

No specific warnings exist for pregnancy or breastfeeding because topical absorption is minimal and the molecule is not known to enter systemic circulation in meaningful amounts. That said this is not medical advice and anyone who is pregnant or nursing should run new skincare choices by a qualified healthcare professional just to stay on the safe side.

Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid does not make the skin more sensitive to sunlight. You can use it morning or night though everyday sunscreen is still recommended as part of a normal routine.

Potential Side Effects/Adverse Reactions

Reactions to topical use can vary from person to person. The following is a list of potential side effects only and most users will not experience them when the ingredient is properly formulated and applied

  • Mild redness or warmth shortly after application
  • Temporary stinging or itching on compromised or freshly exfoliated skin
  • Contact dermatitis in individuals sensitive to benzothiazine derivatives
  • Rare allergic rash accompanied by swelling or hives
  • Discoloration or instability if mixed with very high concentrations of strong acids or peroxides

If any of these effects occur stop using the product immediately and consult a healthcare professional

Comedogenic Rating

Rating: 1/5. The molecule carries a short caprylyl side chain that adds slip without creating a heavy oil film and its bulkier benzothiazine ring limits deep penetration into pores, so it is unlikely to trap dead cells or excess sebum. Most finished formulas using this ingredient sit light on the skin and rinse away cleanly during cleansing. For these reasons it is generally considered suitable for acne-prone or breakout-prone skin. Very oily formulations or poorly balanced emulsions could raise the clogging risk slightly, but that depends more on the overall product base than on this ingredient itself.

Summary

Caprylyloxyphenylamino Dimethyltetrahydro Benzothiazine Carboxylic Acid acts as an antioxidant, a preservative and a skin protectant. Its benzothiazine ring donates electrons to neutralize free radicals, while the caprylyl-linked phenyl group disrupts microbial membranes to curb spoilage. At the same time the molecule settles into the outer skin layers forming a lightweight barrier that helps hold water in and shields against environmental stress.

Though not yet a household name it has been gaining quiet popularity in higher-end moisturizers and serums that advertise clean preservation and photo-stable antioxidants. More mainstream brands are beginning to adopt it as they look for alternatives to traditional parabens and vitamin-based antioxidants that can degrade quickly.

Current data shows a low irritation profile, no known systemic effects and minimal comedogenicity so most users can feel confident using products that feature it. As with any new skincare addition it is wise to perform a small patch test first to rule out personal sensitivities.

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