Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein?

Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein is a plant-based ingredient made from yellow peas. First the pea protein is hydrolyzed, which means it is broken into smaller pieces so it dissolves easily in water and can slip into tiny cracks along the hair shaft. The fragments are then joined to isostearic acid, a fatty acid that comes from vegetable oil, giving the protein a soft buttery feel. Finally the blend reacts with cetearamidoethyl diethylamine to form a quaternary ammonium salt, leaving the finished material with a positive charge that clings to negatively charged, damaged hair. This combination of small peptides, fatty acid and cationic groups makes the ingredient a gentle yet effective conditioner.

Although pea protein has been used in food for decades, its cosmetic form rose to popularity in the last ten years as brands searched for vegan alternatives to animal keratin. Chemists discovered that linking hydrolyzed pea protein to fatty acids and giving it a cationic charge improved its conditioning power. Today it is produced in modern facilities that grind peas, use enzymes to hydrolyze the protein, purify the peptides, attach the isostearoyl groups then quaternize the blend under controlled temperatures and pH.

You will most often find Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein in rinse-off and leave-in hair products such as shampoos, cream conditioners, co-wash formulas, color-protecting treatments, anti-frizz serums, curl creams and deep repair masks.

Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein’s Cosmetic Benefits/Uses

This ingredient is prized for one key role in hair care.

Hair conditioning: The positive charge in the molecule is attracted to damaged areas on the hair surface, forming a smooth film that makes strands feel softer and easier to comb. The fatty acid part adds slip and shine while the pea peptides help fill in rough spots, which together reduce static, tame frizz and cut down on breakage during styling.

Who Can Use Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein

Products featuring this ingredient are generally suitable for all scalp and hair types, including dry, oily, color treated and sensitive. The molecule is large and positively charged so it stays on the hair surface rather than penetrating skin, which keeps the risk of irritation low. People with very fine or low porosity hair may find heavy formulas leave some weight, so lighter leave-in sprays or rinse-off products are a safer pick for them.

Because the protein comes from yellow peas and every other component is plant-derived or synthetically produced, it fits vegan and vegetarian lifestyles. No animal by-products are used at any stage of manufacture.

Current research shows no specific risks for pregnant or breastfeeding women when the ingredient is applied topically. This is not medical advice and anyone who is pregnant or nursing should run new hair care products past a healthcare professional to be safe.

Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein does not make skin or hair more sensitive to sunlight, and it has no known interactions with UV filters or self tanners. It is also free of gluten, soy and nut derivatives, which may be relevant for those with allergies to those materials.

Potential Side Effects/Adverse Reactions

Responses to topical use of Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein vary from person to person. The points below outline potential issues, but they are uncommon when the ingredient is used at standard cosmetic levels.

  • Mild scalp redness or itching in individuals with pea or legume allergies
  • Eye stinging if the product accidentally runs into the eyes before rinsing
  • Temporary weighed-down or greasy feel if too much leave-in product is applied on fine hair
  • Build-up on the hair shaft after prolonged use without clarifying shampoos, which can dull shine
  • Rare allergic contact dermatitis from sensitivity to the quaternary ammonium group

If irritation or any other negative reaction occurs stop using the product and consult a medical professional.

Comedogenic Rating

Rating: 0 / 5 (non-comedogenic)

This molecule is large water loving and carries a positive charge, so it stays on the outer surface of hair and rinses away easily. It does not sink into facial pores or mix with skin oils, which is why formulators consider it non-pore-clogging.

Suitable for acne-prone or breakout-prone skin because it is unlikely to block pores.

Any build-up that can occur happens on the hair shaft, not on facial skin, and is removed with a clarifying shampoo.

Summary

Cetearamidoethyl Diethonium Isostearoyl Hydrolyzed Pea Protein is mainly a hair conditioner. Its positive charge grips damaged spots, the fatty acid side adds slip and shine and the pea peptides fill in rough areas, which together smooth, detangle and protect strands from breakage.

While not as famous as silicone classics or animal keratin, it is gaining ground in vegan and clean beauty lines because it delivers softness without animal ingredients or heavy build-up.

Safety data show a low risk of irritation or allergy for most users when applied in rinse-off or leave-in hair products. Still, skin can vary, so do a quick patch test when trying any new formula to be on the safe side.

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