Cetearamidopropyl Lauroylethyldimonium Methosulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cetearamidopropyl Lauroylethyldimonium Methosulfate?

Cetearamidopropyl Lauroylethyldimonium Methosulfate is a quaternary ammonium salt made by linking fatty alcohols from coconut or palm oil with lauric acid, then adding a small nitrogen-containing group to give the molecule its positive charge. First introduced in the late 1990s, it was designed to offer the soft feel of older conditioning agents without the heavy build-up they sometimes caused. The manufacturing process involves two key steps: an amidation reaction that joins the fatty chain to a protein-like backbone, followed by quaternization which locks in the charge that lets the ingredient bond to hair and skin. Thanks to its mildness and smoothing power it now appears in rinse-off and leave-in conditioners, hair masks, anti-frizz creams, styling lotions, co-wash formulas and a growing number of skin moisturizers where a light, velvety slip is desired.

Cetearamidopropyl Lauroylethyldimonium Methosulfate’s Cosmetic Benefits/Uses

In formulas this ingredient mainly serves two roles that improve how hair products perform and feel.

  • Antistatic: Its positive charge neutralizes the negative charge that builds up on hair strands during washing and drying which cuts down on flyaways and makes hair easier to style.
  • Hair conditioning: It forms a thin, even film over the cuticle that smooths rough patches, adds softness, boosts shine and helps detangle wet or dry hair without weighing it down.

Who Can Use Cetearamidopropyl Lauroylethyldimonium Methosulfate

This ingredient is generally well tolerated by all skin and hair types, including dry, normal, oily and sensitive. Its lightweight film tends not to clog pores or leave heavy residue so it suits fine or easily weighed-down hair too. Those with extremely reactive skin should still keep an eye on how their scalp or face feels, since any cationic ingredient can rarely provoke irritation in hypersensitive individuals.

Cetearamidopropyl Lauroylethyldimonium Methosulfate is normally sourced from coconut or palm oil and contains no animal by-products, making it acceptable for vegans and vegetarians provided the finished product is certified cruelty free.

No specific warnings have been issued for pregnant or breastfeeding women. The molecule is used at low concentrations, does not penetrate deeply and lacks any known hormonal activity. This is not medical advice and anyone who is expecting or nursing should have a doctor review the products they plan to use to be extra safe.

The ingredient does not make skin more sensitive to sunlight and has no known incompatibility with daytime use alongside sunscreen or other UV protectants.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Cetearamidopropyl Lauroylethyldimonium Methosulfate vary from person to person. The points below list potential reactions though most people will never experience them when the ingredient is formulated and used correctly.

  • Mild scalp or skin irritation Slight redness stinging or itching can occur in users with very sensitive skin
  • Contact allergy Rare cases of allergic contact dermatitis have been reported with quaternary ammonium compounds leading to rash or swelling
  • Eye irritation If a product accidentally runs into the eyes it may cause temporary burning or watering
  • Buildup on hair Overuse in leave-in products can leave fine hair feeling coated or limp

If any discomfort or unusual reaction develops stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Comedogenic rating: 1

Cetearamidopropyl Lauroylethyldimonium Methosulfate has a large, positively charged structure that stays on the surface and rinses away easily. It is not oily or waxy, so it rarely blocks pores which keeps the risk of breakouts low.

Most people with acne-prone or breakout-prone skin can use products containing this ingredient without issues.

Because the molecule is water-dispersible any light residue that might remain is removed with normal cleansing which further limits pore congestion.

Summary

Cetearamidopropyl Lauroylethyldimonium Methosulfate is a gentle conditioning agent that reduces static and smooths hair by laying down a thin, charged film on the cuticle. This film masks rough spots, adds slip and makes detangling easier.

You will see it in an expanding range of shampoos, conditioners, leave-ins and lightweight skin creams as brands look for milder plant-derived alternatives to older quats. While it is not yet a household name its popularity is steadily climbing.

Safety reviews show it is well tolerated at the levels used in cosmetics with only occasional reports of mild irritation or allergy. As with any new product perform a patch test first so you can be sure your skin or scalp agrees with it.

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