Cetethyldimonium Bromide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetethyldimonium Bromide?

Cetethyldimonium Bromide is the cosmetic trade name for hexadecylethyldimethylammonium bromide, a quaternary ammonium compound. It is made by reacting long-chain fatty alcohols derived from plant or synthetic sources with dimethylamine, then quaternizing the mixture with ethyl bromide. The result is a positively charged molecule paired with bromide that dissolves well in water and stays stable in creams, lotions and sprays.

The beauty industry began using quaternary ammonium salts in the mid-20th century when formulators noticed their ability to fight germs and keep hair from building static. Cetethyldimonium Bromide found its niche thanks to its balanced chain length and mildness on skin.

You will see this ingredient in rinse-off and leave-on conditioners, detangling sprays, anti-frizz serums, facial cleansers, micellar waters, sheet masks, lightweight moisturizers and even some deodorant creams. Its mix of cleansing power, germ control and texture help has made it a staple in modern personal care labs.

Cetethyldimonium Bromide’s Cosmetic Benefits/Uses

This multifaceted ingredient brings several perks to a formula:

  • Antimicrobial: Its positive charge disrupts the membranes of bacteria and fungi, helping keep products fresher for longer and supporting a cleaner scalp or skin surface.
  • Antistatic: Neutralizes static electricity on hair strands, reducing flyaways and making hair easier to comb.
  • Cleansing: Acts as a mild surfactant that lifts away oil, dirt and leftover styling products without excessive stripping.
  • Emulsifying: Helps water and oil mix smoothly, giving lotions and sprays a stable, even texture that feels light and non-greasy.

Who Can Use Cetethyldimonium Bromide

This conditioning agent is generally friendly to most skin and hair types. It works well for normal, oily and combination skin because its mild surfactant action removes excess sebum without overdrying. Dry or sensitive skin can usually tolerate it thanks to its low irritation profile, though formulas with high percentages can sometimes feel a bit tight on very delicate skin. Those with a known allergy to quaternary ammonium compounds should steer clear as even small amounts could trigger a reaction.

Cetethyldimonium Bromide can be sourced from plant-derived fatty alcohols or fully synthetic feedstocks, so it is typically suitable for vegans and vegetarians. If animal origin is a concern check that the brand confirms a plant or synthetic supply chain.

Pregnant and breastfeeding users are not specifically restricted from topical use because the ingredient is not readily absorbed through intact skin and has no documented hormone-related activity. That said this is not medical advice and anyone who is pregnant or nursing should run any skincare product by a healthcare provider to be safe.

The molecule does not make skin more vulnerable to sunlight and does not require extra sun protection beyond standard daily SPF habits.

Potential Side Effects/Adverse Reactions

Responses to topical Cetethyldimonium Bromide vary from person to person. The following are potential side effects that could occur in rare cases. When used at appropriate levels most users experience none of these issues.

  • Mild skin irritation
  • Redness or stinging on very sensitive skin
  • Contact dermatitis in individuals allergic to quaternary ammonium compounds
  • Eye irritation if the product accidentally gets into the eyes

If any of these reactions occur discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5. Cetethyldimonium Bromide is a water-friendly quaternary ammonium salt that stays mostly on the surface of skin or hair and rinses away easily. It lacks the heavy oily backbone that normally blocks pores so it is considered very low on the clog-pore scale. Most people prone to acne or breakouts can use products containing this ingredient without added risk. If the formula also includes rich butters or waxes the overall product could still feel heavy so always look at the full ingredient list.

Summary

Cetethyldimonium Bromide works as an antimicrobial, antistatic, cleansing and emulsifying agent. Its positive charge binds to negatively charged microbial cell walls for germ control, calms static on hair strands, lifts away light dirt and oil and helps water and oil mingle for smooth stable textures.

While not as famous as cetrimonium chloride or behentrimonium methosulfate this ingredient appears in a steady stream of conditioners, sprays and gentle cleansers because formulators appreciate its mildness and versatility.

Overall safety is high when used at cosmetic levels, with irritation or allergy remaining rare. As with any new skincare or haircare product it is smart to perform a quick patch test first to confirm personal compatibility.

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