Cetoleth-2: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cetoleth-2?

Cetoleth-2 is a synthetic ingredient made by attaching roughly two units of ethylene oxide to naturally occurring fatty alcohols that come from plant oils rich in palmitic and oleic acid. The finished material is an off-white waxy solid that dissolves easily in warm water and oils, making it handy for modern cosmetic labs.

Ethoxylated fatty alcohols first appeared in the 1950s as gentler alternatives to harsh soaps. Over time formulators noticed that shorter ethoxylate chains such as the “2” in Cetoleth-2 provided a good balance between cleaning power and skin feel, so the ingredient found its way into everyday products.

Manufacturing starts with the isolation of C16 and C18 unsaturated fatty alcohols, typically sourced from coconut, palm or rapeseed oil. These alcohols react with ethylene oxide under controlled heat and pressure, producing a mixture that averages two ethoxy groups per molecule. The result is filtered and tested for purity before being shipped to cosmetic companies.

You will most often see Cetoleth-2 in rinse-off cleansers, facial masks, lightweight lotions, hair conditioners, micellar waters and some color-cosmetic removers. Its twin skills of lifting dirt and blending oil with water let formulators simplify recipes and reduce the need for multiple additives.

Cetoleth-2’s Cosmetic Benefits/Uses

In formulas Cetoleth-2 brings two key functions that help products work better and feel nicer on the skin or hair

  • Cleansing: The ingredient lowers the surface tension of water so oils, makeup and daily grime can be lifted away more easily during rinsing. Because it is derived from fatty alcohols it tends to be milder than many sulfate surfactants, supporting a softer after-feel.
  • Emulsifying: Cetoleth-2 acts as a bridge between oil and water, allowing creams or lotions to stay smooth and stable over time. This improves texture, prevents separation and can boost the delivery of active ingredients evenly across the skin.

Who Can Use Cetoleth-2

Cetoleth-2 is considered friendly for most skin types including oily, combination and normal. Dry or sensitive skin usually tolerates it as well because it is milder than many traditional surfactants, though people with very reactive or eczema-prone skin might still prefer ultra-gentle formulas with fewer cleansing agents.

The ingredient is synthetically processed from plant-derived fatty alcohols so products using a plant source are suitable for vegans and vegetarians. If a brand does not specify the origin of its fatty alcohols consumers following a strict vegan lifestyle may want to verify sourcing with the manufacturer.

Pregnant or breastfeeding women are not known to face special risks from topical Cetoleth-2 when used in the usual cosmetic concentrations. This is not medical advice and anyone expecting or nursing should run all skincare choices past a qualified healthcare professional just to be safe.

Cetoleth-2 does not cause photosensitivity and it does not interact with sunscreen filters or other common daytime actives, so no extra sun precautions are required beyond normal SPF use.

Potential Side Effects/Adverse Reactions

Reactions to topical Cetoleth-2 vary from person to person. The issues listed below are possible yet uncommon when the ingredient appears at the low levels typical of finished cosmetics.

  • Mild skin irritation: A small number of users may notice temporary redness or stinging, especially if skin is already compromised
  • Eye irritation: If a cleanser or makeup remover containing Cetoleth-2 gets into the eyes it can cause watering or a brief burning sensation
  • Contact dermatitis: Very rare allergic responses can include itching, rash or swelling in people sensitive to ethoxylated compounds
  • Dryness with overuse: Using multiple high-foaming products that all rely on this surfactant could gradually strip natural oils leading to tightness or flaking

If any discomfort or irritation persists stop use immediately and consult a healthcare professional for further guidance

Comedogenic Rating

Rating: 1 / 5

Cetoleth-2 is highly water soluble thanks to its short ethoxylate chain, so it rinses away rather than lingering in pores. While it is built on fatty alcohols that could in theory contribute to clogging, the added ethoxy groups reduce its oil-like behavior. Formulas also use it at low levels, further lowering any risk of buildup.

Because of this low rating most people prone to acne or blackheads can use products containing Cetoleth-2 without added concern.

On very occlusive leave-on products the overall formula, not just Cetoleth-2, determines clogging potential. Always look at the full ingredient list if breakouts are a recurring issue.

Summary

Cetoleth-2 serves as a gentle cleanser and a reliable emulsifier. It loosens the bond between water and oil so dirt and makeup wash off easily, and its dual-loving structure anchors oil droplets inside water-based lotions keeping textures smooth and stable.

You will not see social media hype about Cetoleth-2 but chemists reach for it often because it is versatile, mild and cost-effective. It works quietly behind the scenes in everyday cleansers conditioners and light creams.

Safety reviews classify it as low risk at cosmetic use levels. Most skin types tolerate it well yet since skin can react unpredictably it is still smart to patch test any new product that contains Cetoleth-2 before using it across larger areas.

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