Cetoleth-20: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cetoleth-20?

Cetoleth-20 is a man-made ingredient created by reacting naturally sourced fatty alcohols from palm or coconut oil—mainly cetyl (C16) and oleyl (C18) alcohols—with about 20 units of ethylene oxide. This process, called ethoxylation, turns the originally waxy alcohols into a water-loving nonionic surfactant that blends oil and water with ease. Nonionic surfactants like Cetoleth-20 have been staples in personal care since the 1950s when formulators looked for milder alternatives to soap-based cleansers. Today, large-scale manufacturers carry out the reaction in pressurized vessels under carefully controlled temperatures to ensure consistent quality and purity. You will most often spot Cetoleth-20 in face and body lotions, cream cleansers, makeup removers, hair conditioners, wash-off masks and lightweight moisturizers where its ability to mix oil and water delivers smooth, stable textures.

Cetoleth-20’s Cosmetic Benefits/Uses

Formulators turn to Cetoleth-20 for two main jobs that improve how a product feels and works on your skin or hair

  • Cleansing: As a gentle surfactant it loosens and lifts dirt, excess oil and makeup so they can be rinsed away without stripping skin or hair of natural moisture
  • Emulsifying: It binds oil and water into a uniform cream or lotion which keeps formulas from separating, gives them a smooth glide and helps active ingredients spread evenly

Who Can Use Cetoleth-20

Cetoleth-20 is generally well tolerated by most skin types including normal, combination, oily and sensitive skin thanks to its mild nonionic nature. Very dry or eczema-prone skin could find high concentrations slightly dehydrating but this is uncommon because the ingredient is typically used at low levels alongside moisturizers.

Because the fatty alcohols come from plant sources like palm or coconut and the rest of the processing is synthetic, Cetoleth-20 is suitable for vegans and vegetarians provided the finished product is certified cruelty free by the brand.

The Cosmetic Ingredient Review panel has found ethoxylated fatty alcohols safe for use in personal care, so products with Cetoleth-20 are generally considered fine for women who are pregnant or breastfeeding. This is not medical advice and anyone expecting or nursing should check with a doctor before starting new skincare to be safe.

Cetoleth-20 does not increase photosensitivity and has no known interactions with sunlight. It is compatible with most other common cosmetic ingredients, both water and oil soluble, which is why formulators use it in such a wide range of products.

Potential Side Effects/Adverse Reactions

Side effects from topical Cetoleth-20 vary from person to person. The points below describe potential reactions only; most people will not experience them when using a properly formulated product.

  • Mild skin irritation such as redness or stinging, more likely on very sensitive skin
  • Dryness or a tight feeling if used in high concentrations without additional moisturizing agents
  • Allergic contact dermatitis in individuals with a specific sensitivity to ethoxylated ingredients
  • Eye irritation should the product accidentally get into the eyes, especially with cleansers

If any of these reactions occur stop using the product and consult a healthcare professional or pharmacist for advice.

Comedogenic Rating

Rating: 1/5

Cetoleth-20 is derived from long-chain fatty alcohols that could in theory clog pores, but the ethoxylation step makes the molecule highly water soluble so it rinses off easily and does not linger on skin like heavier oils. It is usually used at low levels in rinse-off or lightweight leave-on formulas, which further limits any pore-blocking potential. For these reasons its rating lands at 1, meaning it is very unlikely to trigger breakouts in most users. Those who are prone to acne can generally use products containing Cetoleth-20 without extra concern. If the ingredient sits in a very rich cream alongside comedogenic oils or waxes the overall formula could still be problematic, so always consider the product as a whole.

Summary

Cetoleth-20 acts as a mild cleanser and reliable emulsifier by surrounding oil and dirt with its water-loving end, then letting them rinse away while keeping oil-water mixes stable in lotions and conditioners. Its versatility has kept it a quiet workhorse in personal care since the mid-twentieth century, though it is not a headline ingredient like hyaluronic acid or niacinamide. Overall safety is high, with irritation and pore clogging both unlikely when used in typical cosmetic levels. As with any new skincare product it is wise to do a small patch test first to make sure your skin agrees with the full formula.

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