Chicken Extraembryonic Membrane Cell Conditioned Media: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Chicken Extraembryonic Membrane Cell Conditioned Media?

Chicken extraembryonic membrane cell conditioned media is a fluid collected from laboratory cultures of cells taken from the protective membranes that surround a developing chicken embryo. While the name sounds complex, the material itself is basically a nutrient rich broth brimming with proteins, peptides, amino acids and natural sugars the cells release as they grow. These molecules are prized for their ability to draw in moisture and support skin softness.

Researchers first explored extracts from embryonic tissues in the mid twentieth century while looking for gentle but potent skin rejuvenators. Advances in cell culture later allowed companies to move away from crude extracts and instead harvest the clear growth medium surrounding living cells, giving formulators a cleaner more standardized ingredient.

Manufacturing begins with ethically sourced fertilized chicken eggs. Scientists isolate the extraembryonic membrane, place its cells in sterile flasks then feed them a plant based nutrient solution. As the cells multiply they secrete small bioactive compounds into the surrounding liquid. Technicians periodically remove this liquid, filter out any cellular debris, and stabilize it with gentle preservatives so it stays fresh for use in cosmetics.

You will most often see chicken extraembryonic membrane cell conditioned media in hydrating sheet masks, anti aging serums, lightweight moisturizers, soothing eye creams and post procedure recovery gels where rapid surface comfort is desired.

Chicken Extraembryonic Membrane Cell Conditioned Media’s Cosmetic Benefits/Uses

In formulations this ingredient contributes mainly through its strong water binding ability and overall skin conditioning effect

  • Humectant: draws water from the environment and deeper skin layers into the surface, helping keep skin plump and dewy while reducing the appearance of fine lines
  • Skin conditioning: supplies proteins and peptides that soften rough texture, promote a smooth feel and enhance the skin’s protective barrier after everyday stressors

Who Can Use Chicken Extraembryonic Membrane Cell Conditioned Media

This ingredient is gentle enough for most skin types, including dry, normal and combination skin. Its humectant nature makes it especially helpful for dehydrated or mature skin that craves extra moisture. Very oily or acne-prone skin can still benefit in lightweight formulas, although these users may prefer gel textures to avoid a heavy feel.

Because it is sourced from fertilized chicken eggs it is not considered vegan or vegetarian. Those who avoid animal-derived ingredients for ethical or dietary reasons will want to skip products containing this material.

Current data does not show any specific risks for pregnant or breastfeeding women when the ingredient is applied topically. That said this is not medical advice and anyone who is expecting or nursing should consult a healthcare professional before adding new skincare products, just to be safe.

The ingredient does not increase photosensitivity so it will not make skin more prone to sunburn. Standard daily sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Chicken Extraembryonic Membrane Cell Conditioned Media vary from person to person. The effects listed below are only possibilities and are unlikely for the average user when the product is formulated correctly.

  • Redness or mild irritation in very sensitive skin
  • Temporary stinging on compromised or freshly exfoliated skin
  • Allergic response for individuals with an egg protein allergy
  • Breakouts if the overall formula is too rich for oily or acne-prone skin

If you notice any persistent discomfort discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1 / 5

This low score reflects the ingredient’s water based nature and small molecular weight compounds that tend to sit lightly on skin rather than blocking pores. It is mostly composed of proteins peptides and sugars that act as humectants rather than heavy oils or waxes which are the usual culprits behind congestion.

Because of this rating products featuring Chicken Extraembryonic Membrane Cell Conditioned Media are generally suitable for acne prone or breakout prone skin as long as the rest of the formula is also lightweight.

Keep in mind that finished products may pair the ingredient with richer emollients or silicones which could raise the overall pore clogging potential so always look at the full ingredient list if clogging is a concern.

Summary

Chicken Extraembryonic Membrane Cell Conditioned Media serves mainly as a humectant and skin conditioning agent. The proteins peptides and natural sugars it contains pull moisture toward the surface layers and help smooth rough patches giving skin a plump comfortable feel.

Although not yet a household name it appears in a growing number of niche hydrating serums masks and post procedure gels where rapid soothing and lightweight hydration are desired.

Current research and consumer feedback point to a strong safety profile with minimal risk of irritation except in those who have egg related allergies. Still it is smart to perform a quick patch test whenever you bring home a new product to make sure it agrees with your individual skin.

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