Chlamydomonas Reinhardtii Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Chlamydomonas Reinhardtii Extract?

Chlamydomonas Reinhardtii Extract comes from Chlamydomonas reinhardtii, a single-cell green microalga that lives in fresh water. The extract contains a mix of proteins, amino acids, polysaccharides, natural sugars, vitamins and antioxidant molecules that help attract and hold moisture while supporting the skin’s surface.

The alga has been studied since the mid-1900s for its simple genetics and potential in biofuel and food supplements. As researchers began to notice its strong water-binding and soothing traits, cosmetic chemists explored it for skincare. Today many brands turn to this microalga as a plant-based alternative to synthetic moisturizers.

To make the extract, the alga is cultivated in closed, sterile tanks where light, temperature and nutrients are tightly managed. Once enough biomass is produced the cells are harvested, their walls are gently broken through pressure or sound waves, then the soluble fractions are filtered, concentrated and preserved for use in formulas.

You will usually see Chlamydomonas Reinhardtii Extract in hydrating serums, daily moisturizers, sheet masks, anti aging creams, after-sun gels and calming treatments designed to relieve tightness or redness.

Chlamydomonas Reinhardtii Extract’s Cosmetic Benefits/Uses

In skincare formulas this microalga mainly serves two roles that translate into clear benefits for the user

  • Humectant: draws moisture from the environment and deeper skin layers to the surface layer, giving an instant plumping effect and helping reduce the look of fine lines caused by dehydration
  • Skin conditioning agent: smooths and softens the skin by forming a lightweight film that limits transepidermal water loss, leaving the complexion feeling supple and refreshed

Who Can Use Chlamydomonas Reinhardtii Extract

This extract is gentle and lightweight so it suits most skin types including normal, oily, combination, dry and sensitive. Oilier complexions appreciate its water-binding ability without a greasy feel while dry or mature skin can layer it under richer creams for extra hydration. There are no known concerns that make it unsuitable for any particular skin type, though extremely dry or compromised skin may want an added occlusive to lock in the moisture it provides.

Because the ingredient is sourced from microalgae and produced without animal derivatives it is considered vegan and vegetarian friendly, making it a good option for those avoiding animal-based ingredients.

Topical use during pregnancy or while breastfeeding is generally viewed as low risk, but this is not medical advice and anyone who is pregnant or nursing should confirm product choices with a healthcare professional.

The extract does not increase photosensitivity so it can be used morning or night. It also layers well with common actives like vitamin C, niacinamide and exfoliating acids, adding hydration without interfering with their performance.

Potential Side Effects/Adverse Reactions

Responses to Chlamydomonas Reinhardtii Extract vary from person to person. The points below list potential side effects, but they are uncommon when the ingredient is properly formulated and the majority of users experience none of these issues.

  • Transient redness or mild stinging on very sensitive or broken skin
  • Itching or irritation due to individual allergy to microalgae components
  • Rare clogged pores or breakouts if used in an overly heavy formula on acne-prone skin
  • Contact dermatitis if the product is contaminated or improperly preserved

If any of these reactions occur stop using the product and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 1/5 – Chlamydomonas Reinhardtii Extract is water based and lightweight, containing mostly small molecular weight sugars, amino acids and polysaccharides that do not solidify in pores. It lacks heavy oils or waxes that typically trigger comedones so the likelihood of clogging pores is very low.

Suitable for acne-prone or breakout-prone skin in most formulas.

Final pore-clogging risk comes more from the overall product texture and any richer ingredients paired with the extract than from the extract itself.

Summary

Chlamydomonas Reinhardtii Extract works primarily as a humectant and skin conditioning agent. Its natural sugars and amino acids pull water to the skin surface while its light film helps reduce moisture loss, giving a smooth plumped look.

The ingredient is gaining traction as brands search for sustainable plant based hydrators but it is still less common than long-standing players like hyaluronic acid or glycerin.

Topically it is regarded as very safe with a low rate of irritation or pore blockage. As with any new skincare ingredient users should patch test first to confirm personal tolerance.

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