What Is Chlorella Vulgaris Sh-Polypeptide-14?
Chlorella Vulgaris Sh-Polypeptide-14 is a lab designed copy of a small segment of human nerve growth factor, produced inside the freshwater microalga Chlorella vulgaris. Scientists insert the synthesized human gene into the algae, then let the algae’s own cellular machinery build the peptide chain, which is no longer than 53 amino acids and can include natural features like disulfide links or light sugar attachments. After the algae are harvested the peptide is isolated, purified and blended into cosmetic-grade solutions.
The technology behind it grew out of medical research on recombinant proteins in the late 1990s. As peptide science crossed over into beauty labs, formulators noticed that growth-factor inspired chains could signal skin renewal without the stability issues of full proteins. Chlorella proved an eco-friendly host that is easy to culture, so by the early 2010s this peptide started appearing in premium anti-aging creams and scalp serums.
Today you will most often spot Chlorella Vulgaris Sh-Polypeptide-14 in serums, sheet masks, leave-on moisturizers, targeted eye creams, soothing after-sun gels, hair tonics and high-performance conditioners.
Chlorella Vulgaris Sh-Polypeptide-14’s Cosmetic Benefits/Uses
Formulators choose this peptide because it can tackle several beauty concerns at once
- Antimicrobial – helps keep formulas self-preserved for longer shelf life and can support a clearer complexion by limiting surface bacteria
- Antioxidant – neutralizes free radicals generated by UV exposure or pollution, which helps slow the look of premature aging
- Hair Conditioning – coats strands to smooth cuticles, boost softness and reduce static for shinier, easier-to-manage hair
- Skin Conditioning – improves skin texture and suppleness by supporting natural repair signals and maintaining a healthy moisture barrier
- Emollient – adds a light, non-greasy layer that softens and hydrates, leaving skin feeling silky
Who Can Use Chlorella Vulgaris Sh-Polypeptide-14
This peptide is gentle enough for most skin types including dry, normal, combination, oily and even sensitive skin because it is lightweight, non greasy and free of common irritants like fragrance or alcohol. The molecule is too large to clog pores so it suits acne-prone users as well. There are no known reasons it would be unsuitable for specific skin types unless an individual has a rare sensitivity to algae-derived ingredients.
Since the peptide is grown inside microalgae and no animal-derived materials are used at any stage, products containing it are generally considered vegan and vegetarian friendly.
No data point to risks for pregnant or breastfeeding women when the ingredient is applied topically at typical cosmetic levels. Absorption is minimal and it does not contain vitamin A derivatives or hormonal actives. Still, this is not medical advice and anyone who is pregnant or nursing should show their routine to a qualified healthcare provider before use just to be safe.
Chlorella Vulgaris Sh-Polypeptide-14 does not increase photosensitivity so you can apply it during the day. Of course broad spectrum sunscreen is still recommended for overall skin protection.
Potential Side Effects/Adverse Reactions
Reactions to topical Chlorella Vulgaris Sh-Polypeptide-14 vary from person to person. The points below describe potential side effects that may occur in isolated cases. When the ingredient is formulated and used properly most people will not experience any of these issues.
- Transient redness or mild stinging on very sensitive skin
- Localized allergic contact dermatitis in those with an algae or peptide allergy
- Occasional breakouts if the finished product also contains heavy occlusive oils
- Dryness or tightness if layered with multiple strong exfoliants in the same routine
- Eye irritation if a cream migrates into the ocular area
If you notice any discomfort or persistent reaction stop using the product and consult a healthcare professional.
Comedogenic Rating
Rating: 0 / 5
Chlorella Vulgaris Sh-Polypeptide-14 is a water soluble peptide that sits on the surface of skin rather than seeping into pores or mixing with sebum. It has no oily or waxy components so it does not create the kind of occlusive film that can trap debris and trigger blemishes. For these reasons it earns a solid non-comedogenic score of zero.
Suitable for acne-prone or breakout-prone users.
Keep in mind that a finished product’s overall pore-clogging potential also depends on the other ingredients in the formula, so always look at the entire ingredient list when evaluating a product.
Summary
Chlorella Vulgaris Sh-Polypeptide-14 is a lab crafted peptide that offers antimicrobial protection, antioxidant defense, skin and hair conditioning power and a light emollient feel. By mimicking a fragment of human nerve growth factor it sends gentle repair signals that help skin maintain a strong barrier and helps hair cuticles lie flat for smoothness.
While not yet a household name like vitamin C or retinol it is showing up more often in forward-thinking serums, eye creams and scalp formulas thanks to its multitasking benefits and vegan friendly production.
Current data classifies it as low risk with minimal irritation potential when used at typical cosmetic levels. Still, everyone’s skin is unique so it is wise to patch test any new product that features this peptide.