Cholesteryl Hydroxystearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cholesteryl Hydroxystearate?

Cholesteryl hydroxystearate is an ester formed when natural cholesterol is chemically linked with 12-hydroxystearic acid, a fatty acid often sourced from hydrogenated castor oil. The result is a wax-like substance that blends the skin-friendly properties of cholesterol with the cushioning feel of a fatty acid. First explored in the 1970s as chemists searched for more skin-compatible emollients, it soon earned a place in cosmetic labs for its ability to mimic components already found in the skin’s own protective barrier.

The ingredient is produced through a controlled esterification process: purified cholesterol is combined with hydroxystearic acid under heat and mild catalysts until the two molecules bond. After refining and filtration, the finished material appears as an off-white solid that melts easily into oils and creams.

Its silky texture and barrier-boosting nature make it a popular addition to moisturizers, night creams, anti aging serums, eye treatments, lip balms, foundations, solid makeup sticks, after-sun products and certain wash-off masks. Because it is lipid-based yet non-greasy, formulators often use it when they want a rich feel without a heavy finish.

Cholesteryl Hydroxystearate’s Cosmetic Benefits/Uses

This multi-tasking wax offers several practical advantages when blended into personal care formulas:

  • Skin conditioning: helps replenish surface lipids so skin feels softer, smoother and less tight; supports the natural moisture barrier which can improve overall hydration
  • Emollient: fills in microscopic gaps between skin cells, giving products a creamy glide and leaving a supple, velvety after-feel
  • Viscosity controlling: thickens oils and emulsions, stabilizing the formula and preventing separation while contributing to a luxurious texture

Who Can Use Cholesteryl Hydroxystearate

Because it mirrors lipids already found in the skin, cholesteryl hydroxystearate is generally well tolerated by most skin types. Dry, mature or sensitized complexions often appreciate its barrier-supporting richness while normal skin enjoys the silky feel it imparts. Those with very oily or acne-prone skin may find it a bit heavy if used in high concentrations but in lightweight formulas it rarely feels greasy.

The cholesterol portion of the molecule is typically sourced from lanolin or other animal by-products, which makes this ingredient unsuitable for strict vegans and some vegetarians. A handful of suppliers now offer plant-derived or synthetic versions yet they are not yet common, so label readers following a plant-only lifestyle should take note.

Current safety data shows no reproductive or developmental concerns, so products containing cholesteryl hydroxystearate are considered safe for people who are pregnant or breastfeeding. This is not medical advice and anyone expecting or nursing should review their skincare routine with a qualified doctor.

The ingredient does not absorb UV light and is not known to increase photosensitivity. It is also fragrance-free and stable, making it a gentle choice for formulas aimed at sensitive or post-treatment skin.

Potential Side Effects/Adverse Reactions

Individual responses to topical cholesteryl hydroxystearate can vary. The points below outline potential side effects that could occur, though most users will not experience them when the ingredient is properly formulated and used as directed.

  • Mild skin irritation in those with highly reactive skin
  • Allergic contact dermatitis in rare cases of sensitivity to cholesterol derivatives
  • Transient clogged pores or breakouts if applied in very heavy layers on acne-prone areas
  • Milia formation around the eye contour when used in overly rich eye products

If any of these reactions occur stop using the product immediately and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 2/5

Cholesteryl hydroxystearate contains a fatty acid portion that can occlude pores in very rich formulas yet the ester structure and waxy consistency make it less likely to penetrate deeply or build up as quickly as pure oils. Most lab and user reports show only a mild tendency to clog pores which is why it sits at a 2 rather than higher on the scale.

People who break out easily can usually tolerate it when it appears low on an ingredient list or in lightweight emulsions but very heavy balms or sticks that rely on it for structure may feel too occlusive.

Its rating can shift slightly depending on concentration, the presence of other pore-clogging ingredients and the overall texture of the product.

Summary

Cholesteryl hydroxystearate acts as a skin conditioner, an emollient and a viscosity controller. By pairing cholesterol with a fatty acid it slips into the spaces between skin cells, reinforces the moisture barrier, leaves a smooth velvet finish and thickens formulas so creams and sticks stay stable.

It is moderately popular in moisturizers, lip care and makeup sticks. It is not a headline ingredient like hyaluronic acid yet chemists value its silky feel and barrier affinity so it appears in a steady stream of mid to high end products.

Overall safety data is solid with irritation or allergy being rare. When trying any new product that contains this ester do a small patch test first to confirm personal compatibility.

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