Cinnamidopropyltrimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Cinnamidopropyltrimonium Chloride?

Cinnamidopropyltrimonium Chloride is a quaternary ammonium compound created by linking a cinnamic acid derivative to a trimethylammonium group. Cinnamic acid occurs naturally in cinnamon bark and certain balsam resins, but for cosmetic use the molecule is typically synthesized in a lab to ensure purity and consistency. The finished ingredient appears as a clear to pale yellow liquid that dissolves well in water.

The path to its cosmetic popularity began in the early 2000s when formulators looked for gentler conditioning agents able to smooth hair without heavy buildup. Researchers modified the structure of traditional quats by adding a cinnamido group, which delivered a lighter feel and additional static control. Patents followed, and the material soon made its way into salon shampoos and leave-in sprays.

Manufacturing starts with cinnamoyl chloride reacting with a propylamine to form an amide. This intermediate is then quaternized with trimethylamine and finally neutralized with hydrochloric acid, yielding the chloride salt that provides water solubility.

Today Cinnamidopropyltrimonium Chloride appears in rinse-off and leave-on hair products such as shampoos, conditioners, masks, detangling sprays and anti-frizz serums. Its mild profile also suits color-protecting formulas that need conditioning without stripping dye.

Cinnamidopropyltrimonium Chloride’s Cosmetic Benefits/Uses

When added to personal care products this ingredient delivers two main benefits:

  • Antistatic: The positively charged quaternary head binds to negatively charged sites on hair fibers, neutralizing static electricity. This helps keep strands from flying away, clumping or looking frizzy in low-humidity settings.
  • Hair conditioning: It forms a thin, lubricating film that smooths the cuticle, improves softness and eases comb-through on wet or dry hair. Because the molecule is lighter than many conventional quats it conditions without weighing hair down, leaving a clean feel and natural movement.

Who Can Use Cinnamidopropyltrimonium Chloride

This ingredient is generally well tolerated by all scalp and hair types, including oily, dry, sensitive and color treated. Because it is water soluble and light it will not weigh down fine strands and does not leave a greasy residue that might bother oily scalps. There are no known reasons for people with sensitive skin to avoid it but anyone with a confirmed allergy to quaternary ammonium compounds or cinnamon derivatives should proceed with caution.

Cinnamidopropyltrimonium Chloride is synthesized entirely from laboratory sourced raw materials so it contains no animal derived components, making it suitable for vegans and vegetarians. As always cruelty free status depends on the policies of the finished brand rather than the ingredient itself.

No human or animal studies have flagged specific risks for pregnant or breastfeeding women when the compound is used in rinse off or leave on hair products. It is not absorbed significantly through intact skin so systemic exposure is expected to be minimal. That said this is not medical advice and anyone who is pregnant or nursing should review all personal care products with a qualified healthcare professional just to be safe.

The molecule does not increase sensitivity to sunlight. In fact its cinnamido group absorbs a small amount of UV light but the concentration used in hair care is too low to serve as actual sun protection, so normal sun safety practices still apply.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Cinnamidopropyltrimonium Chloride can vary from person to person. The points below list potential outcomes but they are uncommon when the ingredient is properly formulated and used at standard cosmetic levels.

  • Mild scalp or skin irritation such as redness itching or burning
  • Allergic contact dermatitis in individuals sensitized to quaternary ammonium compounds or cinnamon related allergens
  • Eye irritation if the product accidentally drips into the eyes during application or rinsing
  • Product buildup leading to limp or dull hair when very high concentrations are used without adequate rinsing

If you experience any of the above issues stop using the product immediately and consult a healthcare professional or dermatologist

Comedogenic Rating

Rating: 0–1 (very low)

Cinnamidopropyltrimonium Chloride is a water-soluble quaternary ammonium compound that rinses cleanly and does not leave an oily or waxy film on skin. It is used at low levels, mainly in hair care products that have limited contact with facial skin. Because it lacks heavy lipids that could block pores its tendency to cause blackheads or pimples is minimal.

Suitability: safe for most people who are prone to acne or breakouts.

Extra note: if the ingredient appears in a leave-on product that touches the hairline it is wise to wash the area after styling to prevent any residue from mixing with sebum.

Summary

Cinnamidopropyltrimonium Chloride works as an antistatic agent and light hair conditioner. Its positive charge binds to the negative sites on hair, forming a thin smooth film that cuts static, boosts softness and makes detangling easier without weighing strands down. While not as famous as big name silicones or traditional quats it is gaining steady popularity in modern shampoos, conditioners and leave-in sprays thanks to its clean feel and mild profile.

Current safety reviews show it is well tolerated on skin and scalp, with only rare cases of irritation or allergy. As with any new cosmetic, doing a small patch test when trying a product that contains this ingredient is a smart way to make sure it suits your skin.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search