Climbazole: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
Share:
Inside this article:

All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Climbazole?

Climbazole is a lab-made powder that belongs to a group of ingredients called imidazoles. Chemically it is known as 2-butanone 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-, a name that simply points out its chlorine, oxygen and nitrogen parts. It was first studied in the 1970s when researchers were searching for ways to keep scalp flaking under control. After proving helpful in rinse-off hair products it soon found its way into skin care as well.

Today most climbazole comes from a multi-step synthesis that links an imidazole ring to a chlorinated phenoxy base. Because the process is done in a controlled factory setting the final material is very pure and free from plant or animal impurities.

You will mainly spot climbazole in shampoos, scalp tonics and leave-on scalp serums aimed at reducing flakes or oil build-up. It is also added to face masks, lotions, deodorants and anti-aging creams where keeping unwanted microbes at bay helps the formula stay fresh.

Climbazole’s Cosmetic Benefits/Uses

Formulators like climbazole for three key reasons

  • Anti-Seborrheic – Helps cut down the excess oil and flakes linked with seborrheic skin or scalp so hair and skin look cleaner and feel more comfortable
  • Antimicrobial – Slows the growth of yeast and bacteria that can spoil a product or trigger irritation which supports clearer skin and a healthier scalp
  • Preservative – Adds an extra layer of protection against microbes inside the bottle so the formula stays safe and effective for a longer time without heavy use of broad spectrum preservatives

Who Can Use Climbazole

Climbazole is generally suitable for most skin and scalp types. Oily or combination skin often gains the greatest benefit because the ingredient helps curb excess sebum and yeast that thrive in oilier environments. Normal skin can also use it for added protection against microbes. Very dry or highly sensitive skin may want to use lower strengths or less frequent application because any anti-microbial active has the potential to feel a bit drying or tingly on already compromised skin.

Because climbazole is produced entirely through synthetic chemistry it contains no animal-derived substances, making it appropriate for vegans and vegetarians.

No published data points to specific risks for pregnant or breastfeeding women when climbazole is applied topically in cosmetic amounts. Even so, this article is not medical advice and anyone who is pregnant or nursing should show the ingredient list of any new product to a qualified healthcare professional before use.

Climbazole does not cause photosensitivity, so routine daylight exposure is not a concern. It can be paired with sunscreen or used in evening routines without special precautions.

Potential Side Effects/Adverse Reactions

Side effects from topical climbazole vary from person to person. The following are potential, not expected, reactions when the ingredient is used at approved cosmetic levels and most people will not experience them.

  • Mild stinging or burning during the first few minutes of application
  • Temporary redness or flushing
  • Dryness or tight feeling in areas already prone to dehydration
  • Itchiness, especially on broken or inflamed skin
  • Rare cases of contact dermatitis or allergic rash
  • Eye irritation if the product accidentally gets into the eyes

If any of these reactions occur stop using the product and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5

Climbazole is added in tiny percentages, fully dissolves in the final product and has no oily or waxy structure so it is highly unlikely to block pores. Studies and user reports do not link it to increased comedones or breakouts.

Because of this low rating it is generally considered safe for acne prone skin.

If a product containing climbazole does trigger congestion the culprit is more likely richer emollients or heavy silicones in the same formula rather than climbazole itself.

Summary

Climbazole serves as an anti seborrheic, antimicrobial and mild preservative ingredient that disrupts the membranes of yeast and bacteria helping to cut flakes, reduce excess oil and keep formulas fresh.

It enjoys steady but quiet popularity behind the scenes in dandruff shampoos, scalp tonics and a handful of specialty creams rather than in mainstream hero products.

Toxicology reviews rate it as safe at the low levels used in cosmetics with only occasional mild irritation reported. Even so, doing a quick patch test with any new product that contains climbazole is a sensible precaution.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search