Clonal: The Complete Guide To This Aroma Chemical

Curious about this ingredient? In this article we're explaining everything you need to know.
Updated on: August 15, 2025
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We verify all information on this page using publicly available standards from The International Fragrance Association (IFRA) and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability. The odor description reflects Glooshi's firsthand experience with this material, described as accurately as possible; individual perceptions may vary.

What Is Clonal?

Clonal is a single molecule aroma ingredient first introduced to the fragrance industry in 1978 after laboratory work aimed at improving the freshness of classic cologne accords. It is produced through a modern chemical synthesis that starts with plant-derived feedstocks then goes through several catalytic steps to reach high purity. The result is a vegan friendly substance made in a controlled factory setting rather than distilled from natural citrus fruit.

At room temperature Clonal appears as a perfectly clear liquid that looks much like water, a trait that makes handling and blending straightforward in the compounding room. Because the process yields a material with exceptional stability it has become a staple in many perfumers’ toolkits even though it is not as universally stocked as older citrus molecules such as limonene.

Supply is reliable and the cost sits in the mid-range of common aroma chemicals, so it is accessible for fine fragrance houses and consumer product formulators alike. Its renewable production route helps brands meet clean labeling goals which has also driven broader adoption over the past decade.

What Does Clonal Smell Like?

Perfumers place Clonal in the citrus family. On a blotter it opens with the crisp impression of dried orange peel joined by a brisk metal-tinged sparkle that recalls chilled grapefruit zest. A subtle aldehydic lift gives the note extra brightness while a whisper of oceanic freshness keeps it feeling open and airy rather than juicy or sweet.

In the traditional top-middle-base note framework Clonal sits firmly in the top. It flashes off quickly to announce itself yet a portion of the molecule anchors to the blotter so its character can still be detected well into the drydown. That dual behavior lets it bridge the gap between the opening burst of a blend and the heart notes that follow.

Projection is high during the first minutes which helps a perfume feel lively right after application. Thanks to its low volatility compared with most citrus materials traces remain for well over a day providing a gentle echo long after the first impression fades.

How & Where To Use Clonal

Clonal is a cheerful material to handle: it pours easily, blends without fuss and keeps its character even after a few weeks on the shelf. Most perfumers reach for it when a composition needs a dry citrus flash that endures longer than natural orange oil yet feels cleaner than aldehydes alone.

At trace levels it adds a crisp, almost airy sheen that polishes bergamot or grapefruit accords. Around 0.5 % to 1 % of the total formula the metallic side grows louder giving colognes and marine fragrances a sparkling top that projects strongly. Push it closer to 3 % to 5 % and Clonal becomes a starring note, framing modern ozonic fougères or sporty body sprays with a distinctly zesty edge. Beyond that level it can feel sharp and may swamp softer fruits so restraint pays off in delicate blends like floral bouquets.

Its stability makes it equally at home in soaps, shampoos and detergents where natural citrus oils oxidise or fade. In candles it survives the heat well and throws a fresh peel aroma without the sootiness some terpenes develop. It is less convincing in gourmand themes because the dry peel nuance can clash with sweet vanilla and caramel accords. When a perfumer wants citrus lift yet must avoid allergens such as limonene or citral, Clonal is often the first choice.

Preparation is simple: predilute to 10 % in ethanol or dipropylene glycol for easy weighing and smoother blending. The clear liquid mixes readily with most solvents though a quick roll or shake ensures homogeneity before use. No special antioxidants are required thanks to its inherent resistance to oxidation.

Safety Information

As with any aroma ingredient certain precautions and considerations apply when working with Clonal.

  • Always dilute before evaluation: prepare a 1 % to 10 % solution before smelling to avoid overwhelming the nose and reduce risk of irritation.
  • Avoid direct bottle sniffing: waft the scent from a blotter or scent strip rather than inhaling straight from the container.
  • Ensure good ventilation: work in a fume hood or well-aired room to prevent buildup of vapours that could cause headaches or respiratory discomfort.
  • Wear protective gear: gloves and safety glasses shield skin and eyes from accidental splashes.
  • Health considerations: some aroma chemicals can provoke skin irritation or allergic reactions. Consult a healthcare professional before handling if pregnant or breastfeeding. Brief exposure to low concentrations is generally regarded as safe though prolonged or high-level exposure can be harmful.

The points above are only a starting guide. Always consult the latest Material Safety Data Sheet supplied by your vendor and review it regularly for updates. Follow current IFRA guidelines for maximum usage levels in the intended product category to ensure consumer safety and regulatory compliance.

Storage And Disposal

Unopened drums or bottles of Clonal typically hold their full punch for around five years. Once a container is in use expect about three to four years of reliable quality provided you take a few simple precautions.

Refrigeration is not mandatory but a spot in the back of a lab fridge kept at 4-8 °C can add extra months of freshness. If fridge space is tight a cool cabinet away from sunlight heaters and windows works almost as well. Avoid temperature swings as they can pull air in and out of the bottle and accelerate oxidation.

Choose bottles with polycone caps for both neat material and dilutions. The insert forms a tight seal that beats standard screw tops. Dropper bottles seem handy yet they leak vapor and invite oxygen so give them a miss for long term storage.

Headspace management also matters. Top up containers with inert glass beads or transfer the liquid into a smaller bottle as the level drops. Less empty room equals less oxygen and slower degradation.

Label every vessel clearly with the name Clonal its dilution strength date of filling and any hazard symbols. Sharp marker ink on a solvent-resistant label prevents mix-ups later.

Small bench quantities that are no longer needed can be soaked into an absorbent material such as cat litter then disposed of as chemical waste per local regulations. Because Clonal has low water solubility and a high log P it should not be poured neat down the drain. Larger volumes belong in a licensed disposal stream where they will be incinerated or treated to prevent environmental build-up.

Summary

Clonal is a modern citrus aroma molecule that offers a dry orange peel burst with metallic grapefruit sparkle. It lasts longer than most top notes yet still feels airy which makes it a handy bridge between opening freshness and the heart of a perfume.

From colognes and marine scents to soaps and detergents it slips into many accords and keeps its clarity even in tough bases. Stability is excellent cost is mid-range and the renewable vegan origin helps brands tell a greener story.

Keep an eye on dosage as the zesty edge can shout if pushed too high but used with care Clonal is a fun versatile tool that earns its space on any perfumer’s bench.

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