Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract?

Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract is a botanical blend made from two plants that have long been valued in East Asian herbal traditions. The first part comes from the underground stems of Cnidium officinale, a flowering plant related to parsley. The second part is taken from the roots of Glycyrrhiza inflata, a member of the licorice family known for its soothing properties. Together they supply a mix of natural sugars, flavonoids, and antioxidant compounds that help support healthy looking skin.

Interest in these plants began in traditional beauty rituals where crushed roots or decoctions were applied to calm and soften the skin. Modern cosmetic labs refined those practices, using gentle water – or glycerin-based extraction to pull the beneficial molecules from dried plant material. The resulting liquid or powder concentrate is filtered, standardized for quality, and blended into formulas.

You will most often spot this extract in hydrating creams, calming serums, sheet masks, and anti-aging lotions. Brands add it to boost skin comfort, improve texture, and give products a plant-derived marketing edge.

Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract’s Cosmetic Benefits/Uses

This ingredient is prized for one main role in skin care.

Skin conditioning: The natural sugars and flavonoids coat the surface of the skin, drawing in moisture and helping it stay supple. Regular use can leave the complexion feeling softer, smoother, and less tight, which is why formulators often include the extract in products aimed at soothing dryness or mild irritation.

Who Can Use Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract

This plant duo is generally gentle enough for all skin types including sensitive, dry and combination. Its humectant sugars attract water without leaving a greasy film so even oilier complexions tend to tolerate it, though those battling severe acne might prefer lighter gel formulas that contain the extract rather than rich creams.

Because the ingredient is entirely plant derived it fits within vegan and vegetarian lifestyles. No animal byproducts are involved during growing, harvesting or extraction.

Current research has not flagged any topical issues for people who are pregnant or breastfeeding. That said evidence is limited and hormonal skin can behave unpredictably. This is not medical advice so anyone who is expecting or nursing should run new products past a qualified healthcare professional just to be on the safe side.

Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract is not known to make skin more sensitive to sunlight so you can use it both morning and night. Always pair daytime routines with a broad spectrum sunscreen for overall protection.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient differ from person to person. The points below cover possible side effects of topical Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract but most users will not experience them if the product is formulated and used correctly.

  • Mild redness or stinging
  • Itching or dryness from overuse in very sensitive skin
  • Allergic contact dermatitis in individuals allergic to parsley family plants or licorice derivatives
  • Interference with prescription topical steroids due to the anti inflammatory nature of licorice compounds, potentially altering how those medications perform

If you notice any persistent discomfort stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

This extract is largely composed of water-soluble sugars, flavonoids and small amounts of plant oils, all of which are unlikely to block pores. Its light molecular weight lets it sit on the skin’s surface without forming a heavy film, so it rarely triggers congestion. Therefore it is generally suitable for people prone to acne or breakouts.

The only caveat is the final formula: if the extract appears in a very rich cream packed with occlusive waxes, that product—not the extract itself—may pose a clogging risk.

Summary

Cnidium Officinale Rhizome/Glycyrrhiza Inflata Root Extract is mainly a skin-conditioning agent. The natural sugars act as humectants that pull moisture into the outer layer of skin while licorice-derived flavonoids offer mild calming and antioxidant support, leaving skin softer smoother and more comfortable. Although it is not a headline ingredient in mainstream skin care it shows up in niche soothing serums masks and hydrating lotions where formulators want a botanical touch.

Overall safety is high for topical use with very few reports of irritation when the extract is properly formulated. Still every skin is unique so it is smart to patch test any new product containing this ingredient before applying it to a larger area.

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