Cocamidopropyl Morpholine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cocamidopropyl Morpholine?

Cocamidopropyl Morpholine is a coconut-derived ingredient created by joining fatty acids from coconut oil with a small nitrogen-rich ring called morpholine. The result is a water-compatible molecule that loves both oil and water, which makes it handy in personal care formulas. It first appeared in the late 1990s as chemists looked for gentler, plant-based alternatives to older antistatic agents used in hair care.

To make it, manufacturers start with coco fatty acids, react them with a short chain known as 3-aminopropylamine to form an amide link, then introduce morpholine in a controlled reaction step. The finished material is usually supplied as a clear or slightly yellow liquid that dissolves easily into shampoos, conditioners and leave-in sprays.

You are most likely to spot Cocamidopropyl Morpholine in rinse-off and leave-on hair products such as daily shampoos, smoothing conditioners, detangling sprays, color-protecting masks and anti-frizz serums. It can also appear in multitasking styling creams where light conditioning and static control are desired.

Cocamidopropyl Morpholine’s Cosmetic Benefits/Uses

This ingredient plays more than one role in a formula, helping both the product and the hair feel and look better

  • Antistatic: It reduces the buildup of static electricity on hair fibers, which cuts down on flyaways and helps strands lie smoothly for a sleeker appearance
  • Hair Conditioning: Its mild conditioning action leaves hair softer, easier to detangle and less prone to breakage without weighing it down, making it suitable for daily or frequent use

Who Can Use Cocamidopropyl Morpholine

Cocamidopropyl Morpholine is generally suitable for all scalp and hair types, including oily, dry and normal. Its lightweight nature makes it a practical choice for fine or easily weighed-down strands while still offering enough slip for thicker textures. People with very sensitive skin or a known allergy to coconut derivatives should approach products containing it with caution because rare cases of contact irritation have been reported.

The ingredient is sourced from coconut oil and synthesized without animal inputs, so it aligns with vegan and vegetarian preferences. Always check the rest of the product’s ingredient list, as not every formula using it is automatically cruelty-free or plant-based.

Current safety reviews show no evidence that Cocamidopropyl Morpholine poses special risks to pregnant or breastfeeding women when used topically in rinse-off or leave-on hair care. This is not medical advice; anyone who is pregnant or nursing should clear any new personal care product with a healthcare professional.

It does not increase photosensitivity and will not make hair or scalp more prone to sun damage. The ingredient also does not interfere with common hair color treatments or chemical services, so it can be used alongside those routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Cocamidopropyl Morpholine vary from person to person. The points below list potential side effects, but most consumers will not experience them when the ingredient is used at the concentrations typically found in hair products.

  • Mild scalp irritation – a tingling or itchy feeling that usually resolves after rinsing
  • Allergic contact dermatitis – rare red, rash-like patches in individuals sensitive to coconut-based amides
  • Eye irritation – stinging or watering if the product accidentally drips into the eyes during application or rinsing
  • Product buildup – a heavy or coated feel on hair if formulas containing high levels are not rinsed thoroughly

If any negative reaction occurs stop using the product immediately and consult a qualified medical professional

Comedogenic Rating

Rating: 1/5. Cocamidopropyl Morpholine is water soluble and lightweight, so it does not sit on skin or clog pores the way heavier oils and waxes can. Its main job is antistatic control on hair, not lasting skin conditioning, which keeps residue minimal. As a result it is generally suitable for people prone to acne or breakouts.

No studies link it to increased blackheads or pimples, and it rinses off easily during showering. Very sensitive or allergy-prone individuals could still react if the formula contains high levels or other pore-clogging ingredients, so overall product composition matters more than this single component.

Summary

Cocamidopropyl Morpholine acts as an antistatic agent and light hair conditioner. Its balanced structure loves both water and oil, letting it smooth cuticles, cut down on flyaways and add a touch of softness without heaviness. You will spot it in everyday shampoos, conditioners and leave-in sprays, although it is not as common as big-name quats or silicones since it entered the market more recently and is used mainly by brands looking for plant-derived alternatives.

Safety reviews find it low risk for topical use at typical cosmetic levels with only occasional reports of mild irritation or allergy in sensitive users. While it ranks very low in comedogenicity, it is wise to patch test any new product to rule out personal sensitivities and ensure the full formula agrees with your skin and scalp.

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