Copper Aminoacetylaminoimidazolyl Propanoate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Copper Aminoacetylaminoimidazolyl Propanoate?

Copper Aminoacetylaminoimidazolyl Propanoate is an organically bonded form of copper created by linking copper ions to small building blocks of amino acids and an imidazole ring. This union keeps the copper stable and lets it dissolve in water, which makes it easy to add to creams and serums. The ingredient grew out of research into skin identical peptides in the late 1990s when formulators looked for gentler ways to deliver trace minerals to the skin. It is made through a lab process that attaches copper to the amino-rich carrier under carefully controlled pH and temperature, then filters and dries the result into a fine blue-green powder. You are most likely to see it in anti-aging serums, firming masks, lightweight moisturizers and targeted treatment ampoules that promise smoother and fresher looking skin.

Copper Aminoacetylaminoimidazolyl Propanoate’s Cosmetic Benefits/Uses

The main role of this ingredient in skincare is skin conditioning. It helps keep the surface of the skin soft and flexible, supports a healthy moisture balance and can give a refreshed appearance. By-conditioning the skin it may also improve how other active ingredients spread and absorb, leading to a more even feel and finish in the final product.

Who Can Use Copper Aminoacetylaminoimidazolyl Propanoate

This peptide-bound copper suits most skin types including normal, dry, combination and oily because it is water soluble and lightweight rather than oily or occlusive. Sensitive or highly reactive skin can usually tolerate it, yet those who know they react badly to copper salts or metal allergens should proceed carefully since trace metals can still trigger irritation in rare cases.

The compound is made in a lab from mineral copper and plant-derived or synthetic amino acids, so it is generally considered suitable for vegans and vegetarians. No animal-derived raw materials are typically involved in its production.

Available safety data shows no specific concerns for pregnant or breastfeeding women when the ingredient is used topically at cosmetic levels. That said this is not medical advice and anyone who is pregnant or nursing should have a healthcare professional review any skincare they plan to use to be safe.

The ingredient does not increase photosensitivity, so it will not make skin more prone to sunburn. Daily sunscreen is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Copper Aminoacetylaminoimidazolyl Propanoate can vary from person to person. The points below outline potential issues only; most users should not expect to experience them when the ingredient is formulated and used correctly.

  • Mild stinging or burning on application in very sensitive skin
  • Temporary redness or flushing
  • Allergic contact dermatitis in individuals sensitive to copper or peptide complexes
  • Greenish or bluish staining on light fabrics before the product fully absorbs
  • Reduced efficacy or instability if layered immediately with strong acids or chelating agents

If you experience any of the above discontinue use and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5 – Copper Aminoacetylaminoimidazolyl Propanoate is water soluble, lightweight and non-occlusive so it does not trap oils or debris inside pores. It lacks fatty acids or waxes that commonly lead to blocked follicles which is why it sits at the bottom of the comedogenic scale.

That makes the ingredient suitable for acne-prone or breakout-prone skin types.

Worth noting: copper ions can discourage certain bacteria on the skin surface which may offer an extra bonus for those managing blemishes, though the effect is mild at typical cosmetic levels.

Summary

Copper Aminoacetylaminoimidazolyl Propanoate conditions skin by delivering trace copper in a stable, water-friendly form that helps maintain softness, flexibility and a balanced moisture feel. Its peptide carrier keeps the mineral bioavailable while preventing irritation which lets formulas glide on easily and absorb evenly.

The ingredient sits in a growing but still niche category of copper peptides found mostly in specialty serums and masks rather than everyday lotions. Consumers interested in science-forward anti-aging products are driving its slow rise in popularity.

Current data shows it is low risk for most users when applied topically at cosmetic concentrations. As with any new skincare ingredient it is best to perform a simple patch test before full-face use to confirm personal compatibility.

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