Crataegus Monogyna Meristem Cell Culture Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Crataegus Monogyna Meristem Cell Culture Extract?

Crataegus Monogyna Meristem Cell Culture Extract comes from the growing tip, or meristem, of the common hawthorn tree. Scientists take a tiny piece of this young plant tissue and place it in a sterile nutrient solution where the cells multiply. The resulting cell culture is then filtered and processed to create a stable liquid or powder used in skin care.

The extract is mostly made up of plant sugars, amino acids and protective antioxidants that the young cells produce to fuel rapid growth. Because these cells are at an early stage of development, they are rich in compounds that help defend the plant and keep its tissue hydrated, traits that also appeal to skin formulators.

Interest in plant cell culture technology began in the 1990s as brands searched for greener, more sustainable sources of active ingredients. Culturing cells in the lab avoids large-scale harvesting of wild plants and allows consistent quality from batch to batch. Over the past decade hawthorn cell cultures have become popular in European skin care, first appearing in premium anti-aging creams and later spreading to masks, serums and light lotions.

Today you will most often see Crataegus Monogyna Meristem Cell Culture Extract in firming serums, soothing masks, moisturizers aimed at stressed or urban skin and leave-on night treatments that promise a refreshed look by morning.

Crataegus Monogyna Meristem Cell Culture Extract’s Cosmetic Benefits/Uses

In cosmetics this ingredient is valued for one key role: skin conditioning. It helps soften the surface of the skin, supports a smooth feel and may boost moisture retention thanks to the natural sugars and amino acids it carries. Regular use can leave the complexion looking calmer, more supple and visibly healthier, making it a useful addition to both daily moisturizers and targeted treatment products.

Who Can Use Crataegus Monogyna Meristem Cell Culture Extract

This ingredient is generally well tolerated across most skin types. Dry and mature skin often benefit from its hydrating and smoothing properties, while normal and combination skin appreciate its lightweight feel. Oily or acne-prone skin can usually use it too, since the extract itself is not greasy and carries a low risk of clogging pores. Those with extremely sensitive or reactive skin should proceed with a bit more caution only because any botanical component can, in rare cases, trigger irritation.

The extract is sourced entirely from plant cells grown in a lab, with no animal-derived processing agents, making it suitable for both vegetarians and vegans. It also aligns with many clean beauty and sustainability preferences because cell culture avoids overharvesting wild plants.

Pregnant and breastfeeding women are not known to face specific risks from topical use of this extract, as it has no documented hormonal activity or systemic absorption concerns. Still, this is not medical advice. Anyone who is expecting or nursing should show the product to their doctor for personal guidance.

Crataegus Monogyna Meristem Cell Culture Extract does not increase photosensitivity, so there is no special need to change your usual sun protection routine beyond wearing everyday SPF.

Potential Side Effects/Adverse Reactions

Reactions to topical Crataegus Monogyna Meristem Cell Culture Extract differ from person to person. The points below outline potential side effects, though they are uncommon when the ingredient is used correctly and at typical concentrations in finished products.

  • Skin redness or flushing
  • Mild itching or stinging on application
  • Localized dryness if combined with highly astringent actives
  • Allergic contact dermatitis in individuals sensitive to hawthorn or related botanicals

If you notice persistent discomfort or any of the reactions listed, stop using the product and consult a healthcare professional for advice.

Comedogenic Rating

Rating: 0 / 5

Crataegus Monogyna Meristem Cell Culture Extract is water based and contains mostly lightweight sugars, amino acids and antioxidants rather than heavy oils or waxes that can block pores. No studies or user reports link it to breakouts, so it earns a zero on the comedogenic scale.

Suitable for acne-prone skin.

Because formulas vary, pore-clogging risk depends more on the other ingredients in the finished product than on this extract itself.

Summary

Crataegus Monogyna Meristem Cell Culture Extract is a plant cell culture ingredient used mainly to condition skin. Its natural sugars help pull water to the surface, amino acids smooth texture and built-in antioxidants defend against daily stress. These actions together leave skin softer, calmer and more resilient.

The extract sits in a small but growing niche of lab-grown botanical ingredients that appeal to brands looking for sustainable stories. You will find it most often in European serums and creams, though it has not yet reached the same mainstream fame as hyaluronic acid or vitamin C.

Topically it is considered very safe with low risk of irritation or pore blockage. Still, whenever you start a new product, do a quick patch test to make sure it plays well with your own skin.

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