Cudrania Tricuspidata Meristem Cell Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cudrania Tricuspidata Meristem Cell Extract?

Cudrania Tricuspidata Meristem Cell Extract is derived from the cultivated stem cell region of the Cudrania tricuspidata tree, a mulberry family plant native to East Asia. The meristem cells are rich in natural protective compounds like flavonoids and polyphenols that the plant uses to ward off stress in its environment. Cosmetic scientists became interested in these compounds for their ability to neutralize skin-damaging free radicals, and the ingredient began appearing in skincare formulas in the last decade as laboratories refined plant cell culture technology.

To produce the extract, tiny samples of the plant’s meristem tissue are placed in a sterile nutrient medium, allowing the cells to multiply under controlled conditions. This process yields a consistent, sustainable supply of active molecules without harvesting large amounts of the plant itself. Once enough cells grow, they are broken down and the beneficial components are isolated and purified into a water-soluble extract that can be blended into cosmetic bases.

You can now find Cudrania Tricuspidata Meristem Cell Extract in a range of topical products like anti-aging serums, sheet masks, daily moisturizers and brightening treatments where manufacturers want to add an extra boost of antioxidant care.

Cudrania Tricuspidata Meristem Cell Extract’s Cosmetic Benefits/Uses

This plant stem cell extract brings one main benefit to skincare formulas: its strong antioxidant action. By mopping up free radicals created by UV rays and pollution it helps limit the chain reactions that lead to dullness, dryness and fine lines. Regular use of products containing the extract can support a more even skin tone, maintain firmness and extend the overall freshness of the formulation itself since antioxidants also help keep other ingredients stable.

Who Can Use Cudrania Tricuspidata Meristem Cell Extract

This antioxidant extract is generally well tolerated by all skin types, including dry, oily, combination and sensitive skin, because it delivers its benefits without heavy oils or strong acids. People with extremely reactive or allergy-prone skin may still want to monitor how their skin feels when first introducing any new formula that features the ingredient.

The material is sourced from plant cell cultures so it is suitable for vegans and vegetarians. No animal-derived substrates are used during the culture process, although the overall product formula may still contain other non-vegan ingredients depending on the brand.

Current research shows no specific risks for pregnant or breastfeeding individuals when this extract is applied topically. That said this is not medical advice and anyone who is pregnant or nursing should review all skincare products with a qualified healthcare professional to be extra safe.

Cudrania Tricuspidata Meristem Cell Extract does not make skin more sensitive to sunlight so there is no added need for special photoprotection beyond the daily sunscreen already recommended by dermatologists.

Because the extract is water soluble it layers easily with most other cosmetic actives and does not interfere with makeup wear or sunscreen performance.

Potential Side Effects/Adverse Reactions

Sensitivity to the topical use of Cudrania Tricuspidata Meristem Cell Extract can vary from person to person. The points below list potential side effects that could occur yet they remain uncommon when the ingredient is properly formulated.

  • Temporary redness or mild stinging immediately after application
  • Itchiness or a light rash in individuals with plant extract allergies
  • Dry patches if paired with multiple other astringent or exfoliating actives
  • Eye irritation if the product is applied too close to the lash line

If any unwanted reaction develops discontinue use and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Cudrania Tricuspidata Meristem Cell Extract is water based and contains almost no fats or waxes that could accumulate inside pores, which is why it receives a zero on the comedogenic scale. Its primary role in a formula is antioxidant support rather than occlusive moisturization, so it does not create the heavy film that can trap dead cells or sebum. This makes the extract suitable for people who are prone to acne or frequent breakouts. As with any ingredient, overall pore clogging potential depends on the rest of the product so always consider the full ingredient list.

Summary

Cudrania Tricuspidata Meristem Cell Extract is used in skincare for one standout job: defending skin from free radical damage. The cultured meristem cells are packed with flavonoids and polyphenols that donate electrons to neutralize reactive oxygen species before they can dull the complexion or break down collagen. Along the way the extract also helps keep other formula components from oxidizing so the product stays fresh longer.

While it is not yet as famous as vitamin C or green tea, the extract is steadily gaining visibility in serums masks and light lotions that target early aging or urban pollution stress. Its clean safety profile, vegan sourcing and negligible comedogenicity have made it appealing to indie and K-beauty brands looking for gentle plant actives.

Current data show a very low risk of irritation or sensitization for most users, yet individual responses can differ. Whenever trying a new product that features Cudrania Tricuspidata Meristem Cell Extract it is wise to run a quick patch test to make sure your skin agrees with the overall formula.

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