Cyclopropylbimatoprost: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cyclopropylbimatoprost?

Cyclopropylbimatoprost is a lab-created molecule, classified as a fatty acid amide, that features a small three-carbon ring known as a cyclopropyl group. This tweak to its structure sets it apart from its better-known relative bimatoprost, which has been studied for lash-enhancing drugs. Researchers looking for gentler options for skin care isolated this variant and found that it offers strong antioxidant power without the medicinal effects of its parent compound.

The ingredient is produced through a series of precise organic reactions that link the cyclopentyl core to the cyclopropyl side chain, followed by purification to cosmetic grade. Because it is synthesized rather than harvested from plants or animals, it offers reliable purity and is considered vegan friendly.

Brands usually add cyclopropylbimatoprost to leave-on products where antioxidant support matters most. You may see it in lightweight serums, day or night creams, eye creams, sheet masks and targeted anti-aging treatments that promise to fight dullness or early wrinkles.

Cyclopropylbimatoprost’s Cosmetic Benefits/Uses

This ingredient contributes mainly through its antioxidant activity, which translates into several user-friendly perks.

As an antioxidant cyclopropylbimatoprost helps neutralize free radicals created by UV light, pollution and everyday stress. By reducing this oxidative damage it supports a steadier collagen network and can help skin look firmer and more even toned over time. Formulators also value its stability, so the protective effect lasts throughout a product’s shelf life.

Who Can Use Cyclopropylbimatoprost

Cyclopropylbimatoprost is generally well tolerated by most skin types, including dry, oily, combination and mature skin. Its lightweight feel and low oil content make it unlikely to clog pores, so acne-prone users can usually apply it without worry. Extremely sensitive or reactive skin may still sting or flush when any new active is introduced, so these users should add it slowly and watch how their skin responds.

The ingredient is produced entirely in the lab without animal by-products or testing, which makes it suitable for vegans and vegetarians.

There is limited research on the topical use of cyclopropylbimatoprost during pregnancy or while breastfeeding. Although it is not known to penetrate deeply, it belongs to a family of molecules sometimes used in eye medications, so extra care is wise. This information is not medical advice. Pregnant or nursing individuals should check with their doctor before adding any new skincare product that contains this ingredient.

Cyclopropylbimatoprost does not increase photosensitivity. In fact its antioxidant action can help buffer the skin from everyday sunlight exposure, though it should always be paired with a broad-spectrum sunscreen for full protection.

The ingredient layers well with most common actives like niacinamide, peptides and vitamin C. If you use prescription prostaglandin analogs around the eyes speak with your healthcare provider to avoid doubling up on similar compounds.

Potential Side Effects/Adverse Reactions

Side effects from topical cyclopropylbimatoprost differ between individuals. The points below list potential reactions that may happen in rare cases. When the ingredient is used at the levels approved for cosmetics most people will not notice any of these issues.

  • Mild redness or warmth at the application site
  • Temporary itching or tingling
  • Darkening of the skin where the product is applied, especially on thinner areas like the eyelids
  • Unwanted fine hair growth on treated areas if used repeatedly outside its intended zone
  • Allergic contact dermatitis resulting in swelling or flaking
  • Eye irritation or watering if the product migrates too close to the lash line

If you notice any of these effects stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5. Cyclopropylbimatoprost is a small, lab-made molecule that is used at low concentrations and carries very little oily residue, so it rarely blocks pores. Its structure does not form heavy films on the skin and it is typically housed in lightweight serums or creams that rinse clean or absorb quickly. For these reasons it is generally considered suitable for people who are prone to acne or breakouts. As with any ingredient, the finished formula matters, so extremely rich or occlusive bases could still trigger congestion even when this active is present.

Summary

Cyclopropylbimatoprost functions primarily as an antioxidant, scavenging free radicals that form daily from UV exposure, pollution and internal stress. By limiting oxidative damage it helps support collagen, maintain a more even skin tone and preserve overall skin resilience. Though related to bimatoprost, a drug known for lash growth, this cyclopropyl variant is tailored for cosmetic use and does not carry the same medicinal profile.

The ingredient is still a niche player, showing up mostly in forward-thinking anti-aging or brightening products rather than mainstream lines. As awareness of gentle antioxidants grows it may gain more traction, especially among customers looking for vegan, lab-created actives that deliver targeted benefits without heavy textures.

Current data suggest Cyclopropylbimatoprost is safe for topical use in the concentrations allowed by cosmetic regulations, with side effects being uncommon and usually mild. As with any new skincare addition it is wise to perform a patch test when trying a product that contains this ingredient just to be cautious and ensure your skin responds well.

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