Di-C12-20 Alkyl Dimonium Cellulose Sulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Di-C12-20 Alkyl Dimonium Cellulose Sulfate?

Di-C12-20 Alkyl Dimonium Cellulose Sulfate is a modified form of cellulose, the natural fiber that gives plants their structure. Chemists attach medium to long chain fatty groups (between 12 and 20 carbon atoms) and add a gentle sulfate group, turning plain cellulose into a cationic, or positively charged, powder. This charge lets the ingredient cling to the negatively charged surface of hair and skin. First explored in the 1990s as a safer alternative to harsh quats, it gained traction when formulators sought plant based conditioning agents that rinse off easily yet leave a soft feel. Production starts with wood-pulp cellulose that is purified, reacted with fatty alkyl dimethylamine, then treated with sulfur trioxide to introduce the sulfate group. The final material is washed, filtered and dried into a fine, off-white powder that disperses in water. You will see it most often in rinse off products such as shampoos, conditioners and shower gels, and in a few leave on formulas like hair creams or detangling sprays.

Di-C12-20 Alkyl Dimonium Cellulose Sulfate’s Cosmetic Benefits/Uses

Its main role in cosmetics is antistatic conditioning. By neutralizing static charge on hair strands it helps tame flyaways, improves combability and leaves hair feeling smooth without a heavy buildup. The positive charge also lets it lightly coat the skin, providing a soft, conditioned touch in body washes.

Who Can Use Di-C12-20 Alkyl Dimonium Cellulose Sulfate

This conditioning agent is generally well tolerated by all skin and hair types including dry, oily and sensitive because it does not penetrate deeply and rinses off cleanly. People with very reactive or eczema-prone skin should still keep an eye on any formula that contains multiple potential irritants, but the ingredient itself has a low irritation profile.

Di-C12-20 Alkyl Dimonium Cellulose Sulfate is sourced from plant-derived cellulose and plant or synthetic fatty alcohols so it fits vegan and vegetarian lifestyles. No animal-based raw materials or by-products are involved in standard manufacturing.

Topical use during pregnancy or breastfeeding is considered low risk because it stays on the surface of skin and hair, yet this is not medical advice. Anyone who is pregnant or nursing should review new personal care products with a healthcare professional to be extra safe.

The ingredient does not make skin more sensitive to sunlight and can be used year-round without adding photosensitivity concerns.

No other major restrictions apply beyond normal personal sensitivities to cosmetic ingredients.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Di-C12-20 Alkyl Dimonium Cellulose Sulfate differ from person to person. The points below list potential reactions although most people will never experience them when the ingredient is used at appropriate levels in a well formulated product.

  • Mild skin or scalp irritation in very sensitive individuals
  • Contact allergy presenting as redness or itching
  • Transient eye stinging if shampoo or conditioner runs into eyes
  • Hair appearing weighed down if too much product is left on fine hair
  • Interaction with highly anionic actives that could lower overall conditioning performance

If you notice any discomfort stop using the product and consult a medical professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5 – Di-C12-20 Alkyl Dimonium Cellulose Sulfate is a large, water-dispersible polymer that sits on the surface of skin and hair then rinses away easily. It lacks the oily, waxy character that usually blocks pores so the chance of clogging is very low. The slight positive charge helps it bind lightly but does not form an occlusive film. For these reasons it is considered safe for those who are prone to acne or breakouts.

Because this ingredient is most often found in rinse-off products like shampoo and conditioner, it spends limited time on facial skin which further lowers any comedogenic risk.

Summary

Di-C12-20 Alkyl Dimonium Cellulose Sulfate is a plant-derived conditioning polymer that neutralizes static, smooths cuticles and leaves hair or skin feeling soft thanks to its positive charge and mild fatty side chains. It performs these tasks without leaving heavy buildup and works well in both shampoo and body wash formulas.

While not a blockbuster name, it has gained steady popularity among formulators looking for vegan, biodegradable alternatives to traditional quats and it shows up most in mid-priced and eco-focused hair care lines.

Safety data rate it as low irritation, low sensitization and virtually noncomedogenic. Still, skin can be unpredictable so it is always wise to patch test any new product that contains this or any other active ingredient.

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