Diammonium Edta: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Diammonium Edta?

Diammonium Edta, short for diammonium dihydrogen ethylenediaminetetraacetate, is a synthetic salt made by combining ethylenediaminetetraacetic acid with ammonia. The result is a white crystalline powder that dissolves well in water and stays stable across a wide pH range. First explored in the 1940s for industrial water treatment, it soon attracted the cosmetic industry because of its strong ability to bind metal ions that could spoil formulas. Commercial production starts with ethylenediamine, formaldehyde and sodium cyanide, which are reacted to form EDTA; this base is then neutralized with ammonia to create the diammonium form. Today, it is commonly added to facial cleansers, shampoos, bath gels, moisturizers, sheet masks and color-safe hair products where it helps keep the product fresh and effective.

Diammonium Edta’s Cosmetic Benefits/Uses

Formulators rely on Diammonium Edta for two main reasons

  • Antioxidant: By binding trace metals such as iron and copper that can trigger oxidation, it slows down color changes and rancidity, keeping fragrances bright and oils from turning.
  • Chelating: Hard water minerals can reduce foaming, thickeners can break down and preservatives may fail when metals are present. As a chelator, Diammonium Edta grabs these metals so cleansers foam better, creams stay smooth and preservatives work as intended, extending shelf life.

Who Can Use Diammonium Edta

Diammonium Edta is gentle enough for most skin types, including oily, combination, normal and dry skin. Sensitive skin usually tolerates it because it is used in very low amounts though anyone with a history of allergies to ammonium compounds should stay cautious.

The ingredient is made synthetically without animal-derived materials so it is suitable for vegans and vegetarians. Most brands that position themselves as cruelty-free also accept it because no animal testing is needed to produce the raw material.

Pregnant or breastfeeding women can generally use products containing Diammonium Edta as the molecule is not absorbed through intact skin in any meaningful amount. That said this is not medical advice and anyone who is pregnant or nursing should check with a doctor before starting a new skincare product just to be safe.

Diammonium Edta does not cause photosensitivity and will not make the skin more prone to sunburn. It also plays well with most other cosmetic ingredients and does not interfere with sunscreen actives or exfoliating acids.

Potential Side Effects/Adverse Reactions

Reactions to topical Diammonium Edta vary from person to person. The following are potential side effects yet they are uncommon when the ingredient is used at standard cosmetic levels and most people will not experience any problems.

  • Mild skin irritation such as redness or itching, particularly on very sensitive skin
  • Stinging or burning sensation if applied to broken or compromised skin
  • Eye irritation if the product accidentally gets into the eyes
  • In rare cases allergic contact dermatitis marked by persistent rash or swelling
  • Enhanced penetration of other ingredients in the formula which could heighten their own irritation potential

If any discomfort or abnormal reaction occurs stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0/5. Diammonium Edta is a small water-soluble salt that rinses away easily and leaves no oily or waxy film on the skin, so it does not clog pores. Because it sits on the surface only long enough to do its metal-binding job then washes off or stays inert in leave-on products, acne-prone users can generally use it without worry. No studies or anecdotal reports link it to breakouts.

Suitable for those prone to acne or congestion.

As a chelator it can actually boost the performance of preservatives, which helps keep formulas cleaner and less likely to foster pore-clogging microbes.

Summary

Diammonium Edta acts as both an antioxidant helper and a chelating agent. It latches onto trace metals like iron and copper that would otherwise trigger oxidation, so colors stay true and oils stay fresh. By grabbing hard-water minerals it also keeps cleansers foamy, creams stable and preservatives working at full strength.

While not a headline ingredient like hyaluronic acid or vitamin C it appears in countless cleansers, shampoos, lotions and masks because formulators count on its behind-the-scenes support to keep products looking and feeling their best.

Safety data show it is non-sensitizing for most people and it hardly penetrates healthy skin. Still, everyone’s skin is different so it is wise to do a quick patch test when trying any new product that contains Diammonium Edta.

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