Dicapryloyl Cystine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dicapryloyl Cystine?

Dicapryloyl Cystine is a lab made version of the amino acid cysteine that has been linked to two caprylic (octanoic) fatty acid chains. By attaching these medium length oils to the amino acid, chemists create a molecule that is both water friendly and oil friendly, which makes it easy to blend into many cosmetic bases. The ingredient does not come straight from plants or animals but is instead produced through a controlled reaction where purified L-cysteine is joined with caprylic acid using safe activating agents, then filtered and refined to cosmetic grade.

The idea of combining amino acids with fatty acids became popular in the late 20th century when formulators looked for ways to give hair care products extra softness without heavy build-up. Dicapryloyl Cystine was adopted by the industry because cysteine is naturally found in hair’s keratin, so adding a modified form could smooth and protect the cuticle. Today you will most often spot it in shampoos, rinse-off and leave-in conditioners, anti-frizz serums, styling creams and some nourishing hair masks that aim to reduce static and improve manageability.

Dicapryloyl Cystine’s Cosmetic Benefits/Uses

In hair care formulas Dicapryloyl Cystine works mainly in two ways:

  • Antistatic: Helps cut down the electrical charge that makes strands flyaway or cling to brushes. This leads to sleeker looking hair that is easier to style and less prone to frizzing in dry indoor air.
  • Hair conditioning: Coats the hair shaft with a light emollient layer that smooths rough cuticles, boosts softness and adds a natural looking shine without weighing the hair down.

Who Can Use Dicapryloyl Cystine

Dicapryloyl Cystine is considered gentle enough for all skin and scalp types, including sensitive or dry scalps, because the molecule mimics naturally occurring hair proteins while carrying lightweight fatty acids that rarely cause irritation. People with very oily hair or a tendency to develop product buildup may want to use it in rinse-off formulas rather than heavy leave-ins, as the added emollient layer could feel slick if overapplied.

The ingredient is produced synthetically from purified L-cysteine that is typically derived through microbial fermentation, not from animal sources. The attached caprylic chains come from plant oils, so products using this cosmetic grade material are usually suitable for vegans and vegetarians. Anyone following a strict lifestyle should still verify a brand’s full supply chain to be sure.

No studies suggest that Dicapryloyl Cystine poses a risk for women who are pregnant or breastfeeding when it is used topically in standard cosmetic concentrations. This is not medical advice and expectant or nursing mothers should show any hair or skin product to a qualified healthcare professional before regular use, just to be safe.

The ingredient is not known to cause photosensitivity, meaning it will not make skin or scalp more reactive to sunlight. It also does not interfere with common actives such as sunscreens or color-protecting filters, so it fits easily into most hair care routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Dicapryloyl Cystine differ from person to person. The points below list potential side effects, but most users experience none of these issues when the ingredient is used in a properly formulated product.

  • Mild scalp or skin irritation
  • Contact allergy presenting as itching or small red bumps
  • Greasy feel or limp hair if overused in leave-in products
  • Eye stinging or watering if the product accidentally runs into the eyes during rinsing

If any discomfort or unusual reaction occurs stop using the product and seek medical advice if symptoms persist.

Comedogenic Rating

Rating: 1 / 5

Dicapryloyl Cystine carries two short caprylic chains that are considered lightweight and less likely to block pores compared with longer or more saturated fatty acids. It is also most often formulated in rinse-off shampoos and conditioners, which further limits skin contact time. For these reasons its comedogenic score sits near the bottom of the scale.

People who are prone to acne or breakouts can generally use products containing Dicapryloyl Cystine without much concern, especially when the product is washed out. Very occlusive leave-ins applied around the hairline could still contribute to clogged pores in rare cases, so light formulas are the safer choice.

Summary

Dicapryloyl Cystine conditions hair and tames static by wrapping strands in a thin film of cysteine-based protein combined with caprylic fatty acids. This dual nature lets it bond to damaged keratin sites while leaving behind a silky emollient layer for softness shine and easier styling.

While not as famous as argan oil or panthenol it quietly appears in many modern shampoos masks and anti-frizz sprays because it delivers results without heaviness. Formulators appreciate its vegan source versatility and compatibility with other actives.

Safety data show a low risk of irritation allergy or pore clogging at typical use levels so most consumers can enjoy its benefits. As with any new cosmetic it is still wise to patch test first to confirm personal tolerance.

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