Diethylamine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Diethylamine?

Diethylamine is a small, colorless liquid that belongs to the amine family, meaning it contains nitrogen atoms bonded to carbon and hydrogen. Chemically it is written as C4H11N and has a mild fishy smell that is easy to identify. Most commercial diethylamine starts with ethanol and ammonia that are reacted together under heat and pressure, then purified. This method has been refined since the early 1900s, which is around the time chemists began exploring amines for industrial and personal care applications.

Its first use in cosmetics came as formulators noticed that a tiny amount could stabilize the acidity of creams and lotions, making them feel smoother on the skin. Over the decades it has also been valued for its ability to tweak fragrance blends because its own scent can mask or brighten other notes.

Today you will typically find diethylamine in wash-off masks, certain anti-aging serums, lightweight moisturizers, hair conditioners, styling sprays and specialty treatments such as brightening essences. It is almost always used at low levels so the finished product has no obvious amine odor.

Diethylamine’s Cosmetic Benefits/Uses

Below are the main reasons formulators may choose to add diethylamine to a beauty product

  • Buffering – Helps keep the pH of a formula steady so the product stays gentle on skin and remains effective over its shelf life
  • Fragrance – Contributes a light scent that can round out the overall fragrance profile or tone down sharp notes from other ingredients
  • Perfuming – Works in tandem with aromatic oils to enhance scent longevity giving a more pleasant experience during application

Who Can Use Diethylamine

In the percentages typically found in cosmetics diethylamine is considered suitable for most skin types including normal, oily, combination and lightly dry skin because it is used in very small amounts that rarely disturb the skin’s balance. People with very sensitive skin or a compromised skin barrier may want to approach formulas containing amines with caution as their skin can react more easily to slight pH shifts or trace residues.

Diethylamine is produced from ethanol and ammonia, neither of which come from animal sources, so it is generally acceptable for vegans and vegetarians as long as the finished product and brand maintain cruelty free standards.

Current safety data do not flag diethylamine as a concern for women who are pregnant or breastfeeding when used at cosmetic levels. This is not medical advice and anyone who is expecting or nursing should review any skincare product with their healthcare provider before use to be safe.

The ingredient is not known to cause photosensitivity so it should not make skin more reactive to sunlight. Because it has a faint amine scent that can show through if overused, perfumers usually keep the dosage low which further reduces any risk of irritation.

Potential Side Effects/Adverse Reactions

Responses to topical diethylamine can vary from person to person. The list below covers potential side effects yet most users will not experience them when the ingredient is included at appropriate cosmetic levels.

  • Temporary stinging or tingling, especially on freshly exfoliated or broken skin
  • Mild redness or irritation in individuals with highly sensitive skin
  • Contact dermatitis in rare cases of true amine allergy
  • Eye irritation if the product accidentally gets into the eyes
  • Unpleasant odor development if the formula degrades or is stored improperly

If you experience any of these effects discontinue use and consult a medical professional for guidance.

Comedogenic Rating

Rating: 0/5. Diethylamine is a small, highly water-soluble molecule that evaporates or rinses away easily and does not leave an oily film on the skin. Because it is used at very low concentrations and lacks the heavy, waxy character typical of pore-clogging ingredients it earns the lowest possible score. This makes it generally suitable for people who are prone to acne or breakouts.

Worth noting: the final comedogenicity of any product depends on the full formula, so even a non-comedogenic component can appear in a cream that feels rich or occlusive.

Summary

Diethylamine serves three main roles in cosmetics: it buffers formulas to keep pH steady, contributes a faint scent that rounds out fragrance blends and supports perfuming oils by extending their presence after application. It performs these jobs thanks to its basic nitrogen group, which neutralizes acids, and its volatility, which lets just a hint of its own aroma mingle with other notes without lingering on the skin.

The ingredient is more of a behind-the-scenes helper than a star act, so it is not as widely talked about as trendy actives like vitamin C or peptides. Still, chemists appreciate its reliability in small doses and you will quietly find it in a variety of cleansers, lotions and hair products.

Safety data show diethylamine is well tolerated at cosmetic levels, with irritation or allergy remaining rare. As with any new skincare product it is wise to do a quick patch test first so you can spot any unexpected reaction before applying it to a larger area.

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