Diglucosyl Gallic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Diglucosyl Gallic Acid?

Diglucosyl Gallic Acid, also known as 3,5-(Di-D-Glucopyranosyl)Gallic Acid, is a plant-derived molecule formed when gallic acid, a natural antioxidant found in sources like oak bark and green tea, is bonded with two glucose units. The addition of these sugar groups makes the compound water-soluble and skin-friendly, which is a key reason formulators choose it for modern cosmetics.

The ingredient was first explored by cosmetic scientists looking for gentler, plant-based alternatives to traditional conditioning agents. Advances in enzymatic synthesis allowed researchers to attach glucose molecules to gallic acid under controlled lab conditions, creating a stable ingredient that performs well in topical products without the need for harsh solvents.

Production typically involves fermenting plant-sourced gallic acid with specific enzymes that catalyze the glucosylation process. This eco-conscious method keeps temperatures low and avoids petrochemical reagents, aligning with the clean beauty movement.

You will most often see Diglucosyl Gallic Acid in hair masks, leave-in conditioners, color-protecting shampoos, scalp serums and multi-tasking styling creams where a lightweight yet effective conditioning boost is desired.

Diglucosyl Gallic Acid’s Cosmetic Benefits/Uses

When added to hair care formulas Diglucosyl Gallic Acid serves one main purpose that brings several user-visible perks.

As a hair conditioning agent it smooths the cuticle, enhances softness and helps detangle strands. Because it is water-soluble it delivers these benefits without leaving heavy residue, so hair feels light, looks shinier and is easier to manage even in fine or oily hair types.

Who Can Use Diglucosyl Gallic Acid

Because Diglucosyl Gallic Acid is water-soluble and free of heavy oils it suits nearly every hair and scalp type, including fine, oily, curly and color-treated hair. People with sensitive skin or easily weighed-down strands usually tolerate it well since it does not leave an occlusive film. There are no known skin or hair types that should avoid it outright, though anyone with a documented allergy to gallic acid derivatives should proceed cautiously.

The ingredient is synthesized from plant sources without animal by-products or animal testing, making it appropriate for vegans and vegetarians.

No data suggest that Diglucosyl Gallic Acid poses a special risk to women who are pregnant or breastfeeding. That said this is not medical advice, and those who are expecting or nursing should always clear any new personal care product with their healthcare provider to stay on the safe side.

Unlike exfoliating acids or retinoids, Diglucosyl Gallic Acid does not increase photosensitivity so extra sun precautions beyond everyday sunscreen use are unnecessary. The molecule is also odorless and colorless so it will not interfere with fragrance or dye choices in finished formulas.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Diglucosyl Gallic Acid vary from person to person. The following points outline potential reactions that could occur, but they are uncommon when the ingredient is included at typical cosmetic levels in well-formulated products.

  • Mild scalp or skin irritation
  • Allergic contact dermatitis in individuals sensitive to gallic acid derivatives
  • Transient redness or warmth after application
  • Eye stinging if the product accidentally gets into the eyes

If any of these reactions occur stop using the product and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Diglucosyl Gallic Acid is fully water-soluble, contains no oils or waxes and does not form an occlusive film on skin or scalp, so it has virtually no potential to clog pores. Its molecular structure keeps it on the surface until it is rinsed away, further lowering any risk of buildup inside follicles.

Suitable for acne-prone or breakout-prone individuals.

As with any ingredient overall pore-clogging potential also depends on the rest of the formula, so pairing this molecule with heavy butters or waxes could raise the finished product’s comedogenicity even if the ingredient itself is rated 0.

Summary

Diglucosyl Gallic Acid is a plant-derived hair conditioning agent that smooths cuticles, boosts shine and helps detangle without weight. Its two glucose groups attract water while the gallic acid core delivers antioxidant support, allowing hair to feel softer, look glossier and stay protected from daily stressors.

The ingredient is still niche compared with long-standing silicones yet it is gaining traction among clean beauty brands that want a vegan water-light alternative.

Current data show it is low risk for irritation, allergy or pore clogging, making it safe for most users. As with any new cosmetic product, perform a quick patch test to ensure personal compatibility before full use.

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