Diglycol Guanidine Succinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Diglycol Guanidine Succinate?

Diglycol Guanidine Succinate is a lab created ingredient made by combining a moisture loving molecule called diglycol and a skin friendly acid known as succinic acid with guanidine, a nitrogen rich compound found in many living things. The result is a salt that looks like a fine white powder and dissolves easily in water.

Chemists first explored this blend in the early 2000s while looking for gentler ways to boost moisture in skin care. Its balanced structure lets it hold water without feeling sticky, so brands soon began adding it to creams and masks. Making it is straightforward: diglycol and guanidine are mixed under controlled heat then reacted with succinic acid. After filtering and drying, the stable powder is ready to drop into cosmetic formulas.

Today you will spot Diglycol Guanidine Succinate in lightweight facial moisturizers, soothing sheet masks, hydrating serums, after-sun gels and many anti-aging products that promise a soft plump finish.

Diglycol Guanidine Succinate’s Cosmetic Benefits/Uses

This ingredient offers two main perks in skin care

  • Humectant: It attracts water from the air and pulls it into the upper layers of your skin helping keep it smooth firm and comfortable throughout the day.
  • Skin conditioning: By topping up moisture levels it can reduce rough patches improve flexibility and give formulas a silky glide making daily application feel like a treat.

Who Can Use Diglycol Guanidine Succinate

Because it draws water without leaving a greasy film Diglycol Guanidine Succinate suits almost every skin type. Dry or mature skin benefits most from the extra moisture yet its light feel also works for oily and combination skin without clogging pores. Sensitive skin generally tolerates it well since the molecule is mild and has no added fragrance or dyes.

The compound is made entirely from synthetic sources so it contains no animal by-products. That makes it acceptable for both vegans and vegetarians.

No studies have flagged special risks for women who are pregnant or breastfeeding when using this ingredient in topical products. Still this is not medical advice and anyone expecting or nursing should ask a doctor before adding new skincare to their routine just to be safe.

Diglycol Guanidine Succinate does not make skin more prone to sunburn and has no known interactions with sunlight so daytime use is fine with normal sunscreen habits.

Potential Side Effects/Adverse Reactions

Reactions to topical Diglycol Guanidine Succinate differ from person to person. The effects listed below are possible but uncommon when the ingredient is used at normal cosmetic levels.

  • Mild redness or warmth
  • Temporary itching where applied
  • Slight stinging on broken or freshly exfoliated skin
  • Very rare allergic rash in people sensitive to guanidine compounds

If any irritation or unexpected change occurs stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0

Diglycol Guanidine Succinate is totally water soluble with no oily carriers so it does not form a film that could plug pores. Because it simply binds moisture then absorbs or rinses off cleanly it sits at the very bottom of the comedogenic scale.

That means it is generally safe for acne-prone or breakout-prone skin.

Its pore friendly profile holds even in humid climates or under makeup since it does not alter sebum flow or mix with oils that harden inside follicles.

Summary

Diglycol Guanidine Succinate acts as a dual purpose humectant and skin conditioner. Its salt structure pulls water from the air into the outer skin layers then keeps it there, leaving a smooth comfortable finish without heaviness.

The ingredient is not yet a household name but its use is rising in lightweight creams masks serums and after sun gels as brands look for efficient hydrators that feel feather light.

Research and real-world use show a strong safety record with only occasional mild irritation. Even so every skin is unique so doing a small patch test before diving into a new product that contains Diglycol Guanidine Succinate is always a smart move.

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