Dihydrocholesterol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydrocholesterol?

Dihydrocholesterol is a waxy substance that comes from cholesterol. It is often sourced from animal fats such as lanolin found in sheep’s wool although it can also be created in a lab from plant sterols. Chemically it is known as 5-α-cholestan-3-β-ol, which means it has a similar backbone to cholesterol but with all its double bonds removed.

The ingredient first showed up in skin care in the mid-1900s when formulators noticed it could soften skin without the greasiness of heavier oils. Making dihydrocholesterol involves a simple step called hydrogenation where hydrogen is added to regular cholesterol under heat and pressure. This step makes the molecule more stable and less likely to spoil in a jar.

Today you can find dihydrocholesterol in many products that aim to support the skin barrier. It is common in face creams, body lotions, lip balms, masks, soothing ointments, anti aging serums and after-sun products. You will also see it in high-end treatments that mimic the skin’s natural lipids.

Dihydrocholesterol’s Cosmetic Benefits/Uses

This ingredient is valued for a couple of key roles in skin care formulas

  • Emollient – helps smooth and soften the outer layer of skin by filling in tiny cracks which makes the surface feel silky and supple
  • Skin Conditioning – supports the skin’s natural moisture barrier so the skin retains water better which can reduce dryness and flakiness over time

Who Can Use Dihydrocholesterol

Dihydrocholesterol is generally well tolerated by most skin types. Dry, normal and mature skin tend to benefit the most because the ingredient reinforces the moisture barrier and leaves a soft finish without feeling greasy. Combination and slightly oily skin can usually handle it too, although very oily or acne-prone users might prefer lighter emollients depending on the product’s full formula.

Because the bulk of commercially available dihydrocholesterol is still derived from lanolin or other animal fats, it is typically not considered vegan or vegetarian friendly unless a brand clearly states that it has been synthesized from plant sterols. Those who avoid animal-sourced ingredients should check the supplier information or reach out to the manufacturer for confirmation.

No evidence suggests that topical dihydrocholesterol poses a problem for women who are pregnant or breastfeeding, but this is not medical advice. Anyone who is expecting or nursing should review any new skincare product with a qualified healthcare provider.

The ingredient does not increase photosensitivity so it can be used both day and night without heightened risk of sun reaction. It also plays nicely with most other common skincare actives, making it a flexible choice in multi-step routines.

Potential Side Effects/Adverse Reactions

Responses to dihydrocholesterol vary from person to person. The points below outline potential side effects yet most users will not experience them when the ingredient is formulated and used correctly.

  • Skin irritation – mild redness or stinging, typically in very sensitive skin
  • Contact dermatitis – rare allergic reaction more likely in individuals who are allergic to lanolin or wool
  • Clogged pores – possible in acne-prone skin if the overall product is rich or applied too heavily

If any negative reaction occurs stop using the product and seek advice from a dermatologist or healthcare professional.

Comedogenic Rating

Rating: 1/5

Dihydrocholesterol sits low on the comedogenic scale because its molecular structure is close to the lipids naturally found in skin, so it tends to absorb rather than form a heavy film that can trap debris. While it is richer than water-light esters, most tests and anecdotal feedback show little tendency to clog pores unless the finished formula is already very occlusive or used in excess.

That means the ingredient is generally suitable for people who are prone to acne or breakouts, provided the overall product is balanced and not overly greasy.

Keep in mind that formulas combining dihydrocholesterol with high levels of waxes or butters may feel heavier and could raise the pore-clogging risk for very oily skin types.

Summary

Dihydrocholesterol functions mainly as an emollient and skin-conditioning agent. It slips into tiny gaps between skin cells, reinforcing the lipid matrix and creating a softer smoother surface while helping the barrier hold on to moisture.

The ingredient is not a blockbuster name like hyaluronic acid or niacinamide but it maintains steady use in moisturizers, barrier creams and lip care where a cholesterol-like lipid can make formulas feel more luxurious without being greasy.

Safety data show it is well tolerated by most skin types with only rare irritation or allergy concerns linked to its animal-derived source. As with any new skincare product it is wise to run a quick patch test before full use, especially if you have extremely sensitive or acne-prone skin.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search