Dihydroquercetin Pentacaprylate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroquercetin Pentacaprylate?

Dihydroquercetin Pentacaprylate, also called taxifolin pentacaprylate, is a modified form of the natural flavonoid taxifolin. Taxifolin is usually extracted from the wood of the Siberian larch tree and other conifers. To turn it into Dihydroquercetin Pentacaprylate, chemists bond five caprylic acid chains to the original taxifolin molecule. This process, known as esterification, makes the antioxidant more oil-friendly so it can mix well with creams and lotions.

The beauty industry began exploring this ingredient in the early 2000s when formulators looked for plant-based antioxidants that stay stable in oil. Attaching caprylic chains solved the stability issue, letting brands add the power of taxifolin to richer products without it breaking down.

You can now spot Dihydroquercetin Pentacaprylate in face serums, anti aging creams, nourishing masks, daily moisturizers, eye treatments, lip balms and even some high-end sunscreens where a boost of antioxidant defense is welcome.

Dihydroquercetin Pentacaprylate’s Cosmetic Benefits/Uses

This ingredient pulls triple duty in a formula, helping both the product and the skin.

  • Antioxidant: It helps neutralize free radicals created by sun exposure and pollution. By limiting this daily oxidative stress, it supports a smoother brighter look over time
  • Humectant: It attracts water to the skin surface. That extra moisture can make skin feel plumper and look more refreshed throughout the day
  • Emollient: Its oil-loving caprylic tails glide over dry patches and fill in tiny gaps in the skin barrier which leaves the face feeling softer and more comfortable

Who Can Use Dihydroquercetin Pentacaprylate

Most skin types can enjoy this ingredient, including normal, dry, combination and mature skin. Its lightweight emollient feel eases dryness while the oil-compatible base usually avoids a heavy finish so combination and even many oily complexions tolerate it. Exceptionally oil-sensitive or acne-prone users may prefer formulas with lower percentages.

Dihydroquercetin Pentacaprylate is produced from plant-derived taxifolin and caprylic acid with no animal inputs which makes it acceptable for both vegans and vegetarians.

Current research does not flag any special concerns for pregnant or breastfeeding women, yet this is not medical advice and anyone expecting or nursing should consult a doctor before introducing new skincare products.

The ingredient itself does not increase photosensitivity so regular daytime sunscreen habits remain sufficient.

Potential Side Effects/Adverse Reactions

Skin responses differ between individuals. The effects listed below are potential outcomes that are considered uncommon. When the ingredient is formulated at recommended levels most users experience none of these issues.

  • Mild redness or warmth soon after application
  • Temporary stinging on freshly exfoliated or compromised skin
  • Rare allergic contact dermatitis in people sensitive to flavonoids
  • Pore clogging if applied in thick layers on very oily skin
  • Extra dryness when layered with strong leave-on acids or retinoids

If any adverse effect occurs discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1 / 5

Dihydroquercetin Pentacaprylate carries five short caprylic chains that spread easily and absorb without leaving a heavy film. It is typically used at low concentrations, so it is unlikely to block pores for most users. Because the base molecule is a lightweight ester not a waxy butter, it sits at the lower end of the scale.

Acne-prone skin can usually tolerate this ingredient, though very oily complexions may prefer formulas where it appears lower in the ingredient list.

Formulation context matters; pairing it with thick plant butters or high levels of silicones could raise the overall comedogenic load of a product even if the ester itself is mild.

Summary

Dihydroquercetin Pentacaprylate offers antioxidant defense, moisture attraction and a softening emollient touch in one multitasking package. The caprylic tails let the taxifolin core dissolve in oils where it sweeps up free radicals, draws in water molecules for a plumper feel and smooths rough spots by filling micro-gaps in the skin barrier.

While not yet as mainstream as vitamin C derivatives or resveratrol, interest in this ester is rising among indie and premium brands that want a plant-based antioxidant stable in oil phases.

Available safety data shows a low risk of irritation or sensitization and the ingredient is considered safe at standard use levels. As with any new skincare addition it is wise to patch test first, especially for sensitive or reactive skin types.

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