Dihydroxybenzyl Butyrolactone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxybenzyl Butyrolactone?

Dihydroxybenzyl Butyrolactone, also known as 5-(3,4-dihydroxybenzyl)-2-dihydroxyfuranone, is a plant-inspired molecule closely related to natural compounds found in fruits and vegetables rich in polyphenols. Chemically it carries two hydroxyl groups on a benzyl ring attached to a butyrolactone core, a structure that gives the ingredient strong antioxidant properties. Although the compound itself is produced synthetically for purity and consistency, the manufacturing process mimics steps that occur in nature, starting with simple aromatic precursors that are carefully reacted and refined until the final crystalline powder is obtained.

Interest in this molecule began in academic research aimed at isolating potent, stable antioxidants that could outperform vitamin C in topical formulas. As formulators searched for ingredients that defend skin from everyday environmental stress, Dihydroxybenzyl Butyrolactone made its way from the lab bench into commercial skincare lines during the late 2010s. Today it appears in a range of products such as protective day creams, anti-aging serums, after-sun gels, sheet masks and targeted spot treatments, where it is valued for both its efficacy and its compatibility with other active ingredients.

Dihydroxybenzyl Butyrolactone’s Cosmetic Benefits/Uses

This multitasking ingredient supports skin health on several fronts

  • Antioxidant: It neutralizes free radicals generated by UV light, pollution and daily stress which helps slow the appearance of fine lines, uneven tone and dullness. Its stability means it keeps working longer than many common antioxidants, boosting the shelf life and effectiveness of the overall formula
  • Skin Protecting: By reinforcing the skin’s natural barrier and reducing oxidative damage, it can soothe signs of sensitivity and maintain a healthier looking complexion over time

Who Can Use Dihydroxybenzyl Butyrolactone

Dihydroxybenzyl Butyrolactone is considered suitable for all skin types, including dry, oily, combination and even sensitive complexions, thanks to its mild nature and non-comedogenic profile. At typical use levels it does not clog pores or leave a heavy feel so acne-prone skin can usually tolerate it well. No specific skin type is advised to avoid it unless an individual has a known sensitivity to phenolic antioxidants, which is rare.

The molecule is made in a lab without animal-derived raw materials and is not tested on animals in regions that prohibit such practices, making it appropriate for vegans and vegetarians.

No data currently suggest that topical Dihydroxybenzyl Butyrolactone poses a risk during pregnancy or breastfeeding. However this is not medical advice and women who are pregnant or nursing should always clear any skincare product with their physician to be safe.

The ingredient does not increase photosensitivity and can be used morning or night. Pairing it with daily sunscreen is still recommended because free radical protection works best alongside UV filters.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Dihydroxybenzyl Butyrolactone vary from person to person. The points below outline potential reactions that are unlikely to affect the average user when the ingredient is properly formulated.

  • Transient redness or warmth
  • Mild stinging on very compromised or freshly exfoliated skin
  • Allergic contact dermatitis in individuals already sensitized to similar phenolic compounds
  • Temporary dryness if combined with multiple strong actives that also exfoliate or strip oil

If any of these effects occur discontinue use and seek advice from a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Dihydroxybenzyl Butyrolactone is a small water-soluble molecule that lacks the heavy oily chains known to trap debris inside pores. It blends smoothly into lightweight formulas, leaves no occlusive film, and easily rinses off, so it earns the lowest score on the comedogenic scale.

That makes it suitable for people who are prone to acne or routine breakouts.

Because it is typically used at low levels, the ingredient will not raise a product’s overall pore-clogging potential. Users with very oily or congested skin should still check the full ingredient list since other components may be more decisive in how a product behaves.

Summary

Dihydroxybenzyl Butyrolactone functions mainly as an antioxidant and skin-protecting agent. Its two hydroxyl groups quickly neutralize free radicals while the butyrolactone ring stabilizes the molecule so it keeps working longer than many traditional antioxidants. By curbing oxidative stress it helps support the skin’s natural barrier and promotes a brighter, fresher-looking complexion.

Although not yet a mainstream star, its solid performance and compatibility with popular actives such as vitamin C and niacinamide are making it pop up in more modern formulas, especially those focused on daily environmental defense.

Safety data show a very low irritation risk and no tendency to clog pores, so most skin types can enjoy its benefits with confidence. Still, it is wise to patch test any new skincare product just to be sure your skin agrees with the complete formula.

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