Dihydroxychalcone Sulfonic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxychalcone Sulfonic Acid?

Dihydroxychalcone Sulfonic Acid is an organic compound that belongs to the larger family of chalcones, plant inspired molecules known for their antioxidant potential. In this case, chemists have added two hydroxyl groups and a sulfonic acid group to the basic chalcone backbone, giving the ingredient good water solubility and a mild acidic nature that suits skin care formulas.

The compound is not harvested from plants in bulk; instead it is made in the lab through a series of controlled steps. First a standard chalcone is produced by joining an acetophenone and a benzaldehyde derivative. The molecule then goes through selective hydroxylation to add the two hydroxyl groups, followed by sulfonation to attach the sulfonic acid group. Each step is carried out under strict temperature and pH controls to avoid unwanted by-products, and the final material is purified before use in cosmetics.

Formulators first explored chalcone derivatives in the early 2000s when looking for new gentle additives that could soften skin without the heaviness of oils. Dihydroxychalcone Sulfonic Acid stood out because it can bind moisture, smooth rough patches and support a healthy skin feel. Today you will most often find it in water based serums, lightweight moisturizers, sheet masks, soothing gels and anti aging lotions where a light touch is preferred.

Dihydroxychalcone Sulfonic Acid’s Cosmetic Benefits/Uses

In skin care this ingredient is valued for a single key role that brings several visible perks.

Skin Conditioning: Dihydroxychalcone Sulfonic Acid helps skin stay soft and comfortable. By pairing its water attracting groups with a gentle acidic profile, it supports the skin’s natural moisture balance, smooths texture and leaves a silky afterfeel without clogging pores or feeling greasy.

Who Can Use Dihydroxychalcone Sulfonic Acid

Thanks to its lightweight water loving nature, Dihydroxychalcone Sulfonic Acid is generally suitable for most skin types. Oily and combination skin benefit from the non greasy hydration it delivers, while dry skin gains extra moisture without a heavy occlusive layer. Sensitive skin usually tolerates it well because the molecule has a mild acidity and contains no fragrance or known harsh solvents. Those with severely compromised or broken skin should wait until the barrier has calmed before applying products that feature this ingredient.

The compound is produced entirely in the lab and does not rely on any animal derived raw materials, so formulations that include it are typically considered vegan and vegetarian friendly. Always check the finished product label to confirm the entire formula meets personal ethical standards.

No published data indicates a specific risk for women who are pregnant or breastfeeding when this ingredient is applied topically in normal cosmetic concentrations. That said this is not medical advice and anyone who is expecting or nursing should have a discussion with a qualified healthcare provider before adding new products to a routine.

Dihydroxychalcone Sulfonic Acid does not appear to make skin more sensitive to sunlight and can be used morning or night. Standard daily sunscreen use is still recommended to protect against UV damage.

Potential Side Effects/Adverse Reactions

Reactions to topical Dihydroxychalcone Sulfonic Acid vary from person to person. The issues listed below are potential side effects seen in isolated cases and are unlikely for the average user when the ingredient is correctly formulated and used as directed.

  • Mild stinging or warmth upon application, usually short lived
  • Transient redness especially on very sensitive or freshly exfoliated skin
  • Dryness if layered with multiple strong acids or astringents
  • Rare allergic contact dermatitis presenting as itching or small bumps
  • Eye irritation if the product migrates too close to the lash line

If any of these effects occur discontinue use and seek advice from a medical professional or dermatologist.

Comedogenic Rating

Rating: 0. Dihydroxychalcone Sulfonic Acid is a small, water soluble molecule that does not form an oily film on the skin or linger inside pores. It acts mainly as a humectant style skin conditioner, pulling moisture toward the surface rather than sealing it in with heavy lipids. Because it lacks the long chain fatty acids and waxy esters that typically cause pore blockage, the risk of comedone formation is considered negligible.

This makes the ingredient suitable for people who are prone to acne or breakouts.

Its excellent solubility also means it rinses away easily during cleansing, further lowering any chance of residue building up over time.

Summary

Dihydroxychalcone Sulfonic Acid serves chiefly as a skin conditioning agent, binding water to maintain softness and smoothing rough spots without adding weight. The dual hydroxyl groups attract moisture while the sulfonic acid group keeps the molecule comfortably acidic for skin compatibility.

Although chalcone derivatives enjoy some interest among formulators, this specific ingredient is still a quiet performer found mostly in niche hydrating serums, calming gels and lightweight moisturizers rather than mainstream blockbuster products.

Current data shows it is well tolerated with a very low risk profile when used at normal cosmetic levels. As with any new skincare addition it is wise to perform a quick patch test first to confirm individual compatibility.

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