Dihydroxyethyl Soy Glycinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxyethyl Soy Glycinate?

Dihydroxyethyl Soy Glycinate is a plant-derived compound made from soybean fatty acids that have been linked to glycine then modified with two hydroxyethyl groups. On ingredient labels you might also see it written as Di(2-hydroxyethyl)soy-alkylammonioacetate. Because it comes from soybeans it offers a renewable option in hair care formulas.

The ingredient grew popular in the late 1990s when formulators started looking for gentle, plant based conditioners that could stand in for animal sourced proteins. By tweaking the soy fatty acids with amino acids and small alcohol groups chemists created a molecule that clings lightly to hair without weighing it down.

Manufacturing begins with refined soybean oil. The oil is split into fatty acids, which are then reacted with glycine to form a soy glycinate backbone. Controlled addition of ethylene oxide supplies the two hydroxyethyl groups, giving the final molecule its smooth, water friendly character. The finished material is purified into a clear to pale yellow liquid that disperses easily in water.

You will most often find Dihydroxyethyl Soy Glycinate in rinse-off and leave-on products aimed at boosting softness and manageability. Typical placements include shampoos, daily conditioners, deep conditioning masks, leave-in sprays, styling creams and color care treatments.

Dihydroxyethyl Soy Glycinate’s Cosmetic Benefits/Uses

In cosmetics this ingredient serves one main purpose that benefits both the formula and the user.

Hair conditioning: Dihydroxyethyl Soy Glycinate deposits a thin, smooth layer on the hair cuticle, helping strands feel softer and easier to comb. Because the molecule is water friendly it rinses without buildup, so hair retains bounce and shine. It can also reduce static which makes styling simpler and helps hair look less frizzy.

Who Can Use Dihydroxyethyl Soy Glycinate

Because it is mild and water soluble Dihydroxyethyl Soy Glycinate suits most scalp and hair types, including oily, dry, normal and even sensitive scalps that struggle with heavier conditioning agents. Anyone with a known soy allergy should proceed carefully since the raw material is soy based, though the finished molecule contains far less of the proteins that usually trigger reactions.

The ingredient is entirely plant derived and is not tested on animals so it fits vegan and vegetarian lifestyles without reservation.

No studies flag Dihydroxyethyl Soy Glycinate as a concern for women who are pregnant or breastfeeding. That said this information is educational only and not medical advice, so expectant or nursing mothers should show any new hair care product to their doctor before use just to be safe.

Dihydroxyethyl Soy Glycinate does not make skin or hair more sensitive to sunlight, so there is no added need for special sun protection beyond normal good habits.

Potential Side Effects/Adverse Reactions

Responses to topical ingredients vary from person to person. The effects listed below are possible yet unlikely when the ingredient is used at the concentrations found in well formulated hair care products.

  • Mild scalp redness or itching in individuals with very sensitive skin
  • Allergic reaction in people highly reactive to soy derivatives
  • Transient eye irritation if the product accidentally runs into the eyes
  • Build up or limp feel on extremely fine hair when overused without thorough rinsing

If you notice any irritation or discomfort stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Dihydroxyethyl Soy Glycinate is highly water soluble and leaves only an ultrathin conditioning film that rinses clean, so it does not clog pores or sit on the skin the way heavier oils can. Its molecular structure is more akin to a mild surfactant than an occlusive lipid, which explains the non-comedogenic score.

That makes the ingredient suitable for people who are prone to acne or breakouts.

Because it is used almost exclusively in hair care products that are rinsed off or applied mainly to hair lengths, direct and prolonged contact with facial skin is minimal further lowering any clogging risk.

Summary

Dihydroxyethyl Soy Glycinate is a plant based hair conditioner that smooths the cuticle, improves combability and cuts down static by forming a light, water loving layer on each strand. Its gentle action comes from the soy fatty acid backbone combined with glycine and two hydroxyethyl groups, which help it attach to hair without building up.

The ingredient enjoyed a surge of interest when brands began looking for vegan alternatives to animal proteins, though it remains something of a niche choice compared with mainstream silicones and quats.

Overall studies and decades of use show it to be very safe with only rare issues in those sensitive to soy. As with any new cosmetic ingredient it is wise to perform a quick patch test when you try a product containing Dihydroxyethyl Soy Glycinate just to be on the safe side.

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