Dihydroxyisopropyl Palmoylpalmamide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxyisopropyl Palmoylpalmamide?

Dihydroxyisopropyl Palmoylpalmamide is a specialty ingredient derived from palm oil. Chemically it is an amide created when a palm oil ketone dimer reacts with 2-amino-1,3-propanediol, giving a molecule that carries both fatty and water-loving parts. This dual nature lets it blend smoothly into creams and lotions while latching onto moisture and forming a soft, protective film on skin or hair.

The idea of turning palm oil into a skin-friendly amide dates back to the early 2000s, when formulators started looking for plant-based alternatives to mineral oils and animal fats. By tweaking the fatty acids found in palm oil they discovered that coupling them with small sugar-like alcohols created materials that felt lighter yet sealed in hydration. Over the years this led to the commercial launch of Dihydroxyisopropyl Palmoylpalmamide, now made through a controlled amidation process followed by purification to remove excess reactants.

You will most often see this ingredient in daily moisturizers, night creams, anti-aging serums, leave-in hair conditioners, sheet and wash-off masks, hand and body lotions, after-sun gels and barrier-repair balms. Its plant origin, silky finish and multitasking nature make it popular in both premium and mass-market lines.

Dihydroxyisopropyl Palmoylpalmamide’s Cosmetic Benefits/Uses

This multitasker adds value to a wide range of personal care products by supporting four key functions

  • Hair conditioning – smooths the cuticle to reduce frizz, boost shine and make detangling easier without a heavy or greasy feel
  • Humectant – draws water from the air and holds it on the skin surface helping keep skin plump and supple for longer periods
  • Skin conditioning – softens rough patches and improves overall texture leaving skin feeling velvety
  • Skin protecting – forms a light breathable film that shields the skin from dehydration and everyday environmental stress

Who Can Use Dihydroxyisopropyl Palmoylpalmamide

Most skin types tolerate this ingredient well. Its light film forming action helps dry and normal skin hold on to moisture while the non greasy finish suits combination and mildly oily skin. Very oily or severely acne prone complexions might prefer a more weightless humectant but even in these groups negative feedback is uncommon.

Dihydroxyisopropyl Palmoylpalmamide comes from palm oil so it is plant derived and therefore generally acceptable to vegans and vegetarians. Some consumers avoid palm based materials over sustainability concerns so look for brands that certify responsibly sourced palm oil if that matters to you.

No data indicate the molecule poses a risk to pregnant or breastfeeding women when used topically. It is not known to penetrate deeply nor to interfere with hormones. This is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to their healthcare provider just to be safe.

The ingredient does not make skin more sensitive to sunlight and can be worn during the day with or without sunscreen. It is also color safe for treated hair and fragrance free so it layers well with other actives and scented products.

Potential Side Effects/Adverse Reactions

Reactions to Dihydroxyisopropyl Palmoylpalmamide vary from one person to another. The points below outline potential side effects yet most users will not encounter them when the ingredient is properly formulated and used as directed.

  • Mild skin irritation temporary redness or itching mostly in people with very sensitive skin
  • Contact allergy rare cases of rash or swelling in individuals allergic to palm derivatives
  • Pore congestion minor clogging in those already prone to comedones when used in very rich leave on products
  • Scalp buildup dullness or heaviness if applied to hair without adequate cleansing between uses

If any discomfort or unusual reaction occurs discontinue use and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5

Dihydroxyisopropyl Palmoylpalmamide contains a long palm-derived fatty chain that could, in theory, sit inside pores yet its bulky amide structure and twin hydroxyl groups keep it more water friendly than straight oils. The molecule tends to stay on the surface as a thin breathable film rather than migrating deep into follicles which keeps its clogging potential low.

Most people prone to acne can use products with this ingredient without extra breakouts, though very oily or highly congested skin might still prefer ultra-light textures.

Formulation makes a difference: in a heavy butter or thick balm even low-comedogenic ingredients can tip the scale, while in a gel cream this material is unlikely to cause issues.

Summary

Dihydroxyisopropyl Palmoylpalmamide acts as a humectant, skin conditioner, skin protectant and hair conditioning agent. Its palm-based fatty tail smooths and softens while the hydroxyl-rich head attracts water, letting it pull in moisture then lock it under a light occlusive film. The result is skin that feels velvety and hydrated and hair that looks sleek and shiny.

The ingredient is still a niche pick compared with classics like glycerin or silicones yet it is showing up more often in mid-range and prestige formulas thanks to its plant origin and multitasking profile.

Safety data and user feedback rate it as low risk with minimal irritation or allergy reports. As with any new cosmetic ingredient it is smart to do a small patch test before full use, especially if your skin is sensitive.

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