Dihydroxylignoceroyl Phytosphingosine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxylignoceroyl Phytosphingosine?

Dihydroxylignoceroyl Phytosphingosine is a lab made lipid that belongs to the ceramide family, the naturally occurring fats that help keep skin and hair healthy. It is built from phytosphingosine, a plant-derived amino alcohol, that is bonded with lignoceric acid, a long chain fatty acid. This structure gives the ingredient a strong ability to hold water and reinforce the surface of skin and hair.

The cosmetic use of ceramide-type molecules began in the early 1990s when researchers saw how well they mimicked the skin’s own protective barrier. Over time chemists tweaked the structure to make it more stable and easier to blend into creams. Dihydroxylignoceroyl Phytosphingosine is one of those next-generation versions, designed to deliver the same barrier support while dispersing smoothly in both water-based and oil-based formulas.

Manufacturers create it by first fermenting plant sugars to produce phytosphingosine. They then attach lignoceric acid through a controlled reaction, purify the result and mill it into a fine powder. This powder is added to the cool-down phase of a cosmetic batch so its delicate structure stays intact.

You will usually find Dihydroxylignoceroyl Phytosphingosine in moisturizers, anti-aging serums, overnight masks, eye creams, scalp treatments and leave-in hair conditioners. It is prized in products that promise long-lasting hydration or smoother stronger hair.

Dihydroxylignoceroyl Phytosphingosine’s Cosmetic Benefits/Uses

In formulas this ingredient supports both skin and hair care goals in the following ways:

  • Skin conditioning – reinforces the skin barrier, reduces moisture loss, soothes dryness and leaves skin feeling soft and supple
  • Hair conditioning – coats and smooths the hair shaft, helps lock in moisture, reduces breakage and boosts overall shine

Who Can Use Dihydroxylignoceroyl Phytosphingosine

This ceramide-like lipid is gentle enough for nearly every skin type. Dry and sensitive skin often benefit the most because the molecule strengthens the moisture barrier, though normal, combination and oily skin can also use it without feeling heavy or greasy. People with an identified allergy to ceramides or fatty alcohol derivatives should avoid it, otherwise there are no major skin type restrictions.

Dihydroxylignoceroyl Phytosphingosine is produced from plant sugars through fermentation then coupled with a plant-sourced fatty acid, so the ingredient itself is free of animal derivatives. That makes it suitable for vegans and vegetarians, provided the finished product does not contain other animal-based components.

Current cosmetic safety data show no issues for pregnant or breastfeeding women when the ingredient is used topically at typical skincare levels. This is not medical advice, and anyone who is expecting or nursing should confirm any new product with a healthcare professional first to be on the safe side.

The molecule does not absorb UV light or make skin more sensitive to the sun, so it does not raise the risk of sunburn. It also plays well with most other skincare actives, including retinoids and exfoliating acids, without causing instability or irritation.

Potential Side Effects/Adverse Reactions

Reactions to topical Dihydroxylignoceroyl Phytosphingosine vary from person to person. The points below outline potential side effects only; most users will never experience them when the ingredient is properly formulated and used as directed.

  • Mild redness or stinging on very sensitive skin
  • Itching or flaking in rare cases of contact allergy
  • Temporary congestion if layered with heavy occlusives on oily skin
  • Eye irritation if the product accidentally gets into the eyes
  • Weighed-down hair feel when overused in leave-in conditioners

If any negative reaction occurs stop using the product and consult a qualified healthcare provider.

Comedogenic Rating

Rating: 1 / 5

Dihydroxylignoceroyl Phytosphingosine is a large, skin-identical lipid that sits on the surface rather than seeping deep into pores, so it has a very low tendency to trap oil or debris. Its structure closely copies natural ceramides that already exist in healthy skin which further lowers clogging risk. For these reasons a score of 1 is appropriate.

In short, it is generally fine for people who are prone to acne or breakouts.

Keep in mind that the full formula matters: if the product pairs this ingredient with heavy waxes or oils, the overall comedogenicity could rise even though the ceramide itself remains low risk.

Summary

Dihydroxylignoceroyl Phytosphingosine is a lab crafted ceramide mimic that helps skin and hair hold onto moisture, strengthens the protective barrier and smooths rough cuticles. By slotting into the lipid layers on skin and forming a light coating on hair, it reduces water loss, calms dryness and adds softness and shine.

Although not as famous as hyaluronic acid or niacinamide, this next-generation ceramide is showing up in more moisturizers, masks and leave-in conditioners as brands look for advanced barrier boosters.

Safety data rate it as low irritation with minimal allergy reports, making it suitable for most users including sensitive skin, vegans and expectant mothers. As with any new cosmetic ingredient a quick patch test is a smart step before full use.

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