Diisooctyl Succinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Diisooctyl Succinate?

Diisooctyl Succinate is an ester produced when succinic acid, a naturally occurring dicarboxylic acid, reacts with isooctyl alcohol derived from petroleum or plant-based sources such as corn or sugarcane. The result is a clear, lightweight liquid that feels silky on the skin.

The cosmetic world began exploring esters like Diisooctyl Succinate in the 1970s while searching for non-greasy alternatives to traditional oils. Chemists found that this ingredient not only softened skin but also improved the spreadability of creams and lotions. Modern manufacturing relies on a controlled esterification process where heat and a mild catalyst join succinic acid with isooctyl alcohol, followed by purification to remove any excess reactants.

You will often spot Diisooctyl Succinate in moisturizers, lightweight facial oils, anti-aging serums, hydrating masks, primers and makeup products that aim for a smooth, non-sticky finish.

Diisooctyl Succinate’s Cosmetic Benefits/Uses

Formulators choose Diisooctyl Succinate for more than one reason

  • Skin conditioning – helps keep skin soft and supple by forming a light protective film that locks in moisture
  • Emollient – gives products a silky glide, reduces tackiness and improves the overall texture so creams and serums feel pleasant without heaviness

Who Can Use Diisooctyl Succinate

Diisooctyl Succinate suits most skin types including oily, dry, combination and sensitive skin because it is light and non greasy. It softens without clogging pores and rarely triggers stinging, so even reactive skins usually tolerate it well. Extremely acne prone users who break out from any oil like substance might prefer to monitor their skin while introducing it, though its comedogenic rating is low.

The ingredient is synthesized from succinic acid and isooctyl alcohol that come from either petroleum or plant feedstocks, with no animal derived inputs. This makes it acceptable for vegans and vegetarians provided the finished formula uses no other animal ingredients.

No data suggest that topical Diisooctyl Succinate harms pregnant or breastfeeding women. This is not medical advice and anyone who is expecting or nursing should discuss all skincare products with a healthcare professional to stay on the safe side.

The ester does not increase photosensitivity, so it will not make skin more prone to sunburn. It is also compatible with common actives like retinol, vitamin C and niacinamide and does not interfere with sunscreen efficacy.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Diisooctyl Succinate can vary from person to person. The following is a list of potential side effects and they are not expected to be the typical user experience. When formulated correctly most people will not notice any negative effects.

  • Mild skin irritation such as transient redness or stinging in very sensitive individuals
  • Contact dermatitis in the rare event of an allergy to the ester or residual manufacturing impurities
  • Clogged pores leading to small comedones in users who are extremely pore clogging prone
  • Eye irritation if the product accidentally gets into the eyes

If you notice any persistent discomfort, stop using the product and consult a healthcare professional.

Comedogenic Rating

Diisooctyl Succinate scores a 1 on the common 0-5 comedogenic scale. Its molecules are fairly large and sit on the surface rather than settling into pores, and the ester structure avoids the heavy, waxy feel that can trap debris. Reports of acne flare ups are uncommon even among oily skin users.

This low score means the ingredient is generally suitable for people prone to breakouts, although very reactive individuals may still want to keep an eye on how their skin responds.

Keep in mind that the finished formula matters too. If a product also contains rich occlusives like mineral oil or many waxes, the overall chance of congestion can increase regardless of Diisooctyl Succinate’s low rating.

Summary

Diisooctyl Succinate functions as a skin conditioner and emollient. It lays down a thin breathable film that slows moisture loss while its silky slip improves spreadability so creams and serums feel light instead of greasy.

Although not a headline ingredient it is showing up more in modern moisturizers, primers and makeup that aim for a smooth non-sticky finish because it is vegan friendly and works well in lightweight textures.

Safety data and long-term use point to a low risk of irritation or pore clogging, making it suitable for most skin types. Still, patch testing any new product that contains it is the smartest way to confirm your own skin’s comfort.

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