Dimethylol Glycol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dimethylol Glycol?

Dimethylol glycol, also written as (ethylenedioxy)dimethanol, is a lab made ingredient that works mainly as a preservative. Chemists create it by letting ethylene glycol react with a small amount of formaldehyde in water under controlled heat. The reaction adds two “methylol” groups to the glycol backbone which gives the finished material its germ fighting power. The result is usually supplied as a clear liquid or a fine powder that dissolves easily in water based formulas.

Formaldehyde releasing preservatives like dimethylol glycol have been used since the 1970s when brands needed cost effective ways to keep creams from spoiling. While newer options now share the stage this ingredient still shows up in many everyday items because it works well at low doses and is stable across a wide pH range.

You will most often find dimethylol glycol in face masks, rinse off cleansers, moisturizers, anti aging serums, hair conditioners, hand creams and wet wipe solutions. Its ability to limit bacteria and mold growth helps these products stay fresh on the shelf and safe for use over time.

Dimethylol Glycol’s Cosmetic Benefits/Uses

In cosmetics dimethylol glycol serves one key role: it is an antimicrobial preservative. By slowly releasing tiny amounts of formaldehyde it stops the growth of bacteria yeast and mold. This keeps water based products from spoiling so the texture color and scent stay consistent until the last use. A strong preservative system also lowers the risk of skin irritation that can come from contaminated products.

Who Can Use Dimethylol Glycol

Because dimethylol glycol is water soluble and used at very low levels its finished formulas tend to suit normal, oily, dry and combination skin. Sensitive skin may tolerate it too, although people with a known formaldehyde allergy should steer clear since the ingredient slowly releases trace amounts of that compound.

The material is synthesized entirely from petrochemical feedstocks with no animal derived inputs so it is suitable for vegans and vegetarians.

Current safety assessments do not flag dimethylol glycol as a reproductive toxin, meaning products that contain it are generally considered acceptable during pregnancy or while breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should discuss all personal care products with a qualified health professional to be safe.

Dimethylol glycol does not increase photosensitivity and it has no known interactions with sunlight. It is equally stable in day and night formulas.

Potential Side Effects/Adverse Reactions

Individual responses to topical dimethylol glycol can vary. The effects listed below are possible yet unlikely for most users when the preservative is used at industry approved levels.

  • Skin irritation – mild redness or stinging, more common in those with compromised skin barriers
  • Allergic contact dermatitis – itchy rash triggered by formaldehyde sensitization
  • Eye irritation – watering or burning if the product accidentally enters the eyes
  • Cross-reaction with other formaldehyde donors – cumulative exposure can raise irritation risk for people already sensitive to similar preservatives

If any discomfort or unusual reaction develops discontinue use and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0/5. Dimethylol glycol is fully water soluble, used at fractions of a percent and leaves no oily or waxy residue on skin. Because it does not sit in pores or form a heavy film it has virtually no tendency to clog follicles. For that reason it is considered suitable even for skin that breaks out easily. No data suggests it worsens blackheads or pimples, and its antimicrobial action may indirectly help keep blemish-causing germs in check.

Summary

Dimethylol glycol’s main job is to keep cosmetics fresh. It does this by slowly releasing tiny amounts of formaldehyde that stop bacteria, yeast and mold from growing. Thanks to this dependable germ control at very low doses, many formulators still pick it for face masks, lotions and wipes even though flashier preservative systems are now on the market.

Overall safety reviews rate the ingredient as low risk for the average user, with the biggest caution being possible irritation or allergy in people sensitive to formaldehyde. Like any new skincare ingredient it is smart to patch test a product that contains it so you can be sure your skin agrees before making it part of your daily routine.

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