Dioctyldodecyl Sebacate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dioctyldodecyl Sebacate?

Dioctyldodecyl Sebacate is an ester derived from sebacic acid, a dicarboxylic acid most often sourced from castor oil, and two long chain branched alcohols known as 2-octyldodecanol. The result is a clear, lightweight oil that spreads easily on the skin. Chemists first explored this ester in the mid-20th century for industrial lubricants because of its smooth slip and stability, then recognized that the same qualities fit perfectly in personal care. Today its production starts with purifying sebacic acid, reacting it with the alcohols under controlled heat and vacuum, then filtering and refining the final liquid to cosmetic grade standards.

Thanks to its silky texture and compatibility with other ingredients, Dioctyldodecyl Sebacate shows up in a wide range of leave-on products such as facial moisturizers, anti-aging serums, sunscreens, cream blushes, lipsticks, cleansing oils and hair serums. It is valued wherever a non-greasy skin feel and enhanced spreadability are needed.

Dioctyldodecyl Sebacate’s Cosmetic Benefits/Uses

This multitasking ester plays several roles in modern formulations

  • Skin Conditioning: It forms a light, breathable film that softens, smooths and helps reduce moisture loss so skin feels supple
  • Emollient: Its long branched chains fill in microscopic gaps between skin cells, giving formulas a luxurious slip and improving overall texture without a heavy or sticky afterfeel
  • Solvent: It dissolves oil-soluble active ingredients, pigments and UV filters, helping create uniform, stable blends while boosting the performance of other components

Who Can Use Dioctyldodecyl Sebacate

This lightweight ester suits most skin types, including dry and normal skin that crave extra softness, as well as combination skin looking for slip without a greasy finish. Oily or very acne-prone users generally tolerate it too because it has a low tendency to clog pores, although individual responses can vary and breakout-prone skin should watch for any increase in blemishes.

Dioctyldodecyl Sebacate is made from plant-derived sebacic acid and synthetic alcohols, so it is free of animal by-products and fits vegan and vegetarian lifestyles.

No studies show specific risks for those who are pregnant or breastfeeding, and the ingredient is widely used in cosmetics sold to the general public. That said, this is not medical advice. Anyone who is expecting or nursing should review all personal care products with a qualified healthcare provider to be safe.

The ester does not increase photosensitivity, so it will not make skin more prone to sunburn. As always, daily sunscreen is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Dioctyldodecyl Sebacate differ from person to person. The issues listed below are possible but not common, and most users experience none of them when the ingredient is properly formulated and used as directed.

  • Mild skin irritation such as redness or itching in extremely sensitive individuals
  • Rare allergic contact dermatitis in people allergic to esters or other components in the formula
  • Temporary increase in breakouts for skin that is highly congestion-prone when combined with heavier occlusive ingredients
  • Eye irritation if the product accidentally gets into the eyes

If any uncomfortable reaction occurs stop using the product and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1 / 5. Dioctyldodecyl Sebacate has a branched structure that spreads thinly and absorbs rather than sitting in thick layers, so it does not trap dead cells or excess oil the way heavier plant butters and waxes can. It is therefore unlikely to block pores for most users. Acne-prone or breakout-prone skin usually tolerates it well, although reactions always depend on the full formula and individual skin behavior. Some formulators even use this ester to thin out richer oils and lower the overall comedogenic load of a product.

Summary

Dioctyldodecyl Sebacate acts as a skin conditioner, emollient and solvent. Its long branched chains glide across the skin forming a light breathable film that reduces moisture loss and leaves a silky feel. The same structure slips between skin cells to smooth texture while dissolving oil-soluble actives, pigments and UV filters for more even application.

Though not a headline-grabbing ingredient, it enjoys steady use in moisturizers, sunscreens, color cosmetics and hair serums because formulators count on its reliable slip and low greasiness. Consumers rarely notice it by name yet benefit from the elegant feel it gives to many everyday products.

Safety data show a low risk of irritation, allergy or pore clogging, and it is vegan friendly. As with any new skincare ingredient, doing a simple patch test when trying a product that contains Dioctyldodecyl Sebacate is a prudent step for sensitive or reactive skin types.

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